Synthesis and evaluation of novel analogues of mangiferin as potent antipyretic

Asian Pacific Journal of Tropical Medicine

Volumn 4, Issue 11, 2011, Pages 866-869

  Kant Singh, Shashi ^a   Sinha, Saurabh K ^b   Prasad, S K ^b   Kumar, R ^b   Bithu, Bhawani S ^b   Sadish Kumar, S ^c   Singh, P ^d  

^a Varanasi College of Pharmacy   (India)

^b BANARAS HINDU UNIVERSITY   (India)

^c Institute of Technology and Sciences   (India)

^d Udai Pratap College   (India)

Author keywords

Antipyretic; Mangifera indica; Mangiferin

Indexed keywords

5 (N 2 METHYL PHENYLAMINO METHYLENO) MANGIFERIN; 5 (N 4 METHYL PHENYLAMINO METHYLENO) MANGIFERIN; 5 (N ALPHA NAPTHYLAMINE METHYLENO) MANGIFERIN; 5 (N PARA CHLOROPHENYLAMINO METHYLENO) MANGIFERIN; 5 (N PARA METHOXYPHENYLAMINO METHYLENO) MANGIFERIN; 5 (N PHENYLAMINO METHYLENO) MANGIFERIN; 5 (N,N DIPHENYLAMINO METHYLENO) MANGIFERIN; ACETYLSALICYLIC ACID; ALCOHOL; ANTIPYRETIC AGENT; CYTOKINE; MANGIFERIN; SALARETIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIMANG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPYRETIC ACTIVITY; ARTICLE; BARK; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG ISOLATION; DRUG MEGADOSE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FEVER; INFRARED SPECTROSCOPY; MANGO; MELTING POINT; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT STEM; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RECTUM TEMPERATURE; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROSCOPY;

ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEVER; GLYCOSIDES; MANGIFERA; MICE; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS; SACCHAROMYCES CEREVISIAE; TREATMENT OUTCOME; XANTHONES;

EID: 81155144668     PISSN: 19957645     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1995-7645(11)60210-1     Document Type: Article

References (12)

1. Vinothapooshan G, Sundar K Immunomodulatory activity of various extracts of Adhatoda vasica Linn. in experimental rats. Afr J Pharm Pharmacol 2011, 5:306-310.
2. Wauthoz N, Balde A, Balde ES, Damme MV, Duez P Ethnopharmacology of Mangifera indica L. bark and pharmacological studies of its main c-glucosylxanthone, mangiferin. Int J Biomed Pharm Sci 2007, 1:112-119.
3. Singh SK, Kumar Y, Kumar SS, Sharma VK, Dua K, Samad A Antimicrobial evaluation of mangiferin analogues. Indian J Pharm Sci 2009, 71:328-331.
4. Olabinri BM, Olaleye MT, Bello OO, Ehigie LO, Olabinri PF In vitro comparative antioxidative potentials of mango and pawpaw leaf extracts. Int J Trop Med 2010, 5:40-45.
5. Wang H, Ye G, Tang Y, Zhu H, Ma R, Sun Z, et al. High-performance liquid chromatographic method for the determination of mangiferin in rat plasma and urine. Biomed Chromatogr 2006, 20:1304-1308.
6. Pardo-Andreu GL, Delgado R, Núñez-Sellés AJ, Vercesi AE Mangifera indica L. extract (Vimang®) inhibits 2-deoxyribose damage induced by Fe (III) plus ascorbate. Phytother Res 2006, 20:120-124.
7. Perrucci S, Fichi G, Buggiani C, Rossi G, Flamini G Efficacy of mangiferin against Cryptosporidium parvum in a neonatal mouse model. Parasitol Res 2006, 99:184-188.
8. Rodeiro I, Cancino L, Gonza'lez JE, Morffi J, Garrido G, Gonza'lez RM, et al. Evaluation of the genotoxic potential of Mangifera indica L. extract (Vimang), a new natural product with antioxidant activity. Food Chem Toxicol 2006, 44:1707-1713.
9. Mancini DAP, Torres RP, Pinto JR, Mancini-Filho J Inhibition of DNA virus: Herpes-1 (HSV-1) in cellular culture replication, through an antioxidant treatment extracted from rosemary spice. Braz J Pharm Sci 2009, 45:127-133.
10. McKay DL, Blumberg JB A review of the bioactivity of South African herbal teas: Rooibos (Aspalathus linearis) and Honeybush (Cyclopia intermedia). Phytother Res 2007, 21:1-16.
11. Mao J, Yang L, Shi Y, Hu J, Piao Z, Mei L, et al. Crude extract of Astragalus mongholicus root inhibits crop seed germination and soil nitrifying activity. Soil Biol Biochem 2006, 38:201-208.
12. Schieber A, Ullrich W, Carle R Characterization of polyphenols in mango puree concentrate by HPLC with diode array and mass spectrometric detection. Inno Food Sci Emerg Technol 2000, 1:161-166.