Knockout of the Na,K-ATPase α2-isoform in cardiac myocytes delays pressure overload-induced cardiac dysfunction

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 8, 2013, Pages

  Rindler, Tara N ^a   Lasko, Valerie M ^a   Nieman, Michelle L ^a   Okada, Motoi ^a   Lorenz, John N ^a   Lingrel, Jerry B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Adrenocorticotropic hormone; Blood pressure regulation; Na,K ATPase signal transduction; Transaortic constriction

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CORTICOTROPIN; CRE RECOMBINASE; MYOSIN HEAVY CHAIN BETA; ATP1A2 PROTEIN, MOUSE; ATRIAL NATRIURETIC FACTOR; BETA MYOSIN HEAVY CHAIN PROTEIN, MOUSE; BRAIN NATRIURETIC PEPTIDE; INTEGRASE; MESSENGER RNA; MYOSIN HEAVY CHAIN; PROTEIN C FOS; PROTEIN C JUN;

AORTA CONSTRICTION; ARTICLE; BLOOD PRESSURE REGULATION; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; HEART FAILURE; HEART FUNCTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEMODYNAMICS; HYPERTENSION; KNOCKOUT MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SYSTOLIC BLOOD PRESSURE; ANIMAL; BLOOD PRESSURE; CHEMICALLY INDUCED DISORDER; ECHOGRAPHY; GENE INACTIVATION; GENETICS; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE; METABOLISM; METHODOLOGY; MOUSE; MOUSE MUTANT; PHYSIOLOGY; VASOCONSTRICTION;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; ATRIAL NATRIURETIC FACTOR; BLOOD PRESSURE; GENE KNOCKOUT TECHNIQUES; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; INTEGRASES; MICE; MICE, KNOCKOUT; MYOCARDIUM; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; NATRIURETIC PEPTIDE, BRAIN; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RNA, MESSENGER; SODIUM-POTASSIUM-EXCHANGING ATPASE; VASOCONSTRICTION; VENTRICULAR DYSFUNCTION, LEFT;

MLCS; MLOWN;

EID: 84878424333     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00594.2012     Document Type: Article

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