Hypertension from chronic central sodium chloride in mice is mediated by the ouabain-binding site on the Na, K-ATPase α 2-isoform

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 301, Issue 5, 2011, Pages

  van Huysse, James W ^a,b   Dostanic, Iva ^c   Lingrel, Jerry B ^c   Hou, Xiaohong ^a   Wu, Hengwei ^a  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Central nervous system; Cerebrospinal fluid; Gene targeted mice; Intracerebroventricular infusion; Knockout knockin; Ouabain like substance; Potassium adenosine 5' triphosphatase; Sodium

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA2; HYPERTENSIVE FACTOR; OUABAIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; BLOOD PRESSURE MONITORING; CEREBROSPINAL FLUID; CONTROLLED STUDY; GENE TARGETING; GENOTYPE; HYPERTENSION; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TELEMETRY;

ANIMALS; BINDING SITES; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; BRAIN; CARDENOLIDES; DISEASE MODELS, ANIMAL; HEART RATE; HYPERTENSION; INFUSIONS, INTRAVENTRICULAR; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTATION; OUABAIN; SAPONINS; SODIUM CHLORIDE; SODIUM-POTASSIUM-EXCHANGING ATPASE; TELEMETRY; TIME FACTORS;

EID: 80355134439     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01216.2010     Document Type: Article

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