Growth hormone level at admission and its evolution during refeeding are predictive of short-term outcome in restrictive anorexia nervosa

British Journal of Nutrition

Volumn 109, Issue 12, 2013, Pages 2175-2181

  Nogueira, Juan P ^a   Valéro, René ^a,b   Maraninchi, Marie ^a   Lorec, Anne M ^b   Samuelian Massat, Catherine ^b   Bégu Le Corroller, Audrey ^b   Nicolay, Alain ^a,b   Gaudart, Jean ^b   Portugal, Henri ^a,b   Vialettes, Bernard ^a,b  

^a INSERM   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Anorexia nervosa; Growth hormone; Insulin like growth factor 1; Outcomes

Indexed keywords

ADIPOCYTOKINE; ESTRADIOL; GHRELIN; GLUCOSE; GROWTH HORMONE; INSULIN; LEPTIN; LIOTHYRONINE; RESISTIN; SEX HORMONE; SOMATOMEDIN C; TESTOSTERONE; THYROID HORMONE; THYROXINE;

ADULT; ANOREXIA NERVOSA; ARTICLE; BODY COMPOSITION; BODY FAT; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; ENERGY EXPENDITURE; ESTRADIOL BLOOD LEVEL; FAT MASS; FEMALE; FREE LIOTHYRONINE INDEX; GLUCOSE BLOOD LEVEL; GROWTH HORMONE BLOOD LEVEL; HEALTH STATUS; HOMEOSTASIS; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; PREDICTION; PROGNOSIS; PROSPECTIVE STUDY; REFEEDING; RELAPSE; REMISSION; RESTRICTIVE ANOREXIA NERVOSA; SHORT COURSE THERAPY; THYROID HORMONE BLOOD LEVEL;

ADIPOKINES; ADIPOSITY; ADULT; ANOREXIA NERVOSA; CASE-CONTROL STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMAN GROWTH HORMONE; HUMANS; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; LINEAR MODELS; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; RECURRENCE; TREATMENT OUTCOME;

EID: 84878422402     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S000711451200431X     Document Type: Article

References (25)

1. De Alvaro MT, Munoz-Calvo MT, Barrios V, et al. (2007) Regional fat distribution in adolescents with anorexia nervosa: effect of duration of malnutrition and weight recovery. Eur J Endocrinol 157, 473-479. (Pubitemid 350018451)
2. Haas VK, Kohn MR, Clarke SD, et al. (2009) Body composition changes in female adolescents with anorexia nervosa. Am J Clin Nutr 89, 1005-1010.
3. Lucas AR, Beard CM, O'Fallon WM, et al. (1991) 50-year trends in the incidence of anorexia nervosa in Rochester, Minn.: a population-based study. Am J Psychiatry 148, 917-922.
4. Misra M & Klibanski A (2010) Neuroendocrine consequences of anorexia nervosa in adolescents. Endocr Dev 17, 197-214.
5. Miller CA & Golden NH (2010) An introduction to eating disorders: clinical presentation, epidemiology, and prognosis. Nutr Clin Pract 25, 110-115.
6. Argente J, Caballo N, Barrios V, et al. (1997) Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in patients with anorexia nervosa: effect of short-and long-term weight recuperation. J Clin Endocrinol Metab 82, 2084-2092. (Pubitemid 27287565)
7. Warren MP (2011) Endocrine manifestations of eating disorders. J Clin Endocrinol Metab 96, 333-343.
8. Meguerditchian C, Samuelian-Massat C, Valero R, et al. (2009) The impact of weight normalization on quality of recovery in anorexia nervosa. J Am Coll Nutr 28, 397-404.
9. Treasure J, Claudino AM & Zucker N (2010) Eating disorders. Lancet 375, 583-593.
10. Becker AE, Grinspoon SK, Klibanski A, et al. (1999) Eating disorders. N Engl J Med 340, 1092-1098.
11. Berntsen S, Hageberg R, Aandstad A, et al. (2008) Validity of physical activity monitors in adults participating in free living activities. Br J Sports Med 44, 657-664.
12. Audi L, Mantzoros CS, Vidal-Puig A, et al. (1998) Leptin in relation to resumption of menses in women with anorexia nervosa. Mol Psychiatry 3, 544-547. (Pubitemid 28515532)
13. Scacchi M, Ida Pincelli A & Cavagnini F (2003) Nutritional status in the neuroendocrine control of growth hormone secretion: the model of anorexia nervosa. Front Neuroendocrinol 24, 200-224. (Pubitemid 37329472)
14. Thissen JP, Underwood LE & Ketelslegers JM (2003) Regulation of insulin-like growth factor-1 in starvation and injury. Nutr Rev 57, 167-176.
15. Golden NH, Kreitzer P, Jacobson MS, et al. (1994) Disturbances in growth hormone secretion and action in adolescents with anorexia nervosa. J Pediatr 125, 655-660. (Pubitemid 24318447)
16. Misra M, Miller KK, Bjornson J, et al. (2003) Alterations in growth hormone secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism. J Clin Endocrinol Metab 88, 5615-5623. (Pubitemid 38033024)
17. Fazeli PK, Lawson EA, Prabhakaran R, et al. (2010) Effects of recombinant human growth hormone in anorexia nervosa: a randomized, placebo-controlled study. J Clin Endocrinol Metab 95, 4889-4897.
18. Scacchi M, Pincelli AI, Caumo A, et al. (1997) Spontaneous nocturnal growth hormone secretion in anorexia nervosa. J Clin Endocrinol Metab 82, 3225-3229. (Pubitemid 27419061)
19. Brick DJ, Gerweck AV, Meenaghan E, et al. (2010) Determinants of IGF1 and GH across the weight spectrum: from anorexia nervosa to obesity. Eur J Endocrinol 163, 185-191.
20. Counts DR, Gwirtsman H, Carlsson LM, et al. (1992) The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins. J Clin Endocrinol Metab 75, 762-767.
21. Llopis MA, Granada ML, Cuatrecasas G, et al. (1998) Growth hormone-binding protein directly depends on serum leptin levels in adults with different nutritional status. J Clin Endocrinol Metab 83, 2006-2011. (Pubitemid 28496329)
22. Fazeli PK, Misra M, Goldstein M, et al. (2010) Fibroblast growth factor-21 may mediate growth hormone resistance in anorexia nervosa. J Clin Endocrinol Metab 95, 369-374.
23. Inagaki T, Lin VY, Goetz R, et al. (2008) Inhibition of growth hormone signaling by the fasting-induced hormone FGF21. Cell Metab 8, 77-83.
24. Kliewer SA & Mangelsdorf DJ (2010) Fibroblast growth factor 21: from pharmacology to physiology. Am J Clin Nutr 91, 254S-257S.
25. Dostalova I, Kavalkova P, Haluzikova D, et al. (2008) Plasma concentrations of fibroblast growth factors 19 and 21 in patients with anorexia nervosa. J Clin Endocrinol Metab 93, 3627-3632.