Association between the genetic polymorphisms of glutathione S-transferase (GSTM1 and GSTT1) and the clinical manifestations in sickle cell anemia

Blood Cells, Molecules, and Diseases

Volumn 51, Issue 2, 2013, Pages 76-79

  de Oliveira Filho, Romério Alencar ^a   Silva, Géssyka JerÔnimo ^a   de Farias Domingos, Igor ^a,b   Hatzlhofer, Betânia Lucena Domingues ^a,b   da Silva Araújo, Aderson ^b   de Lima Filho, José Luiz ^a   Bezerra, Marcos André Cavalcanti ^a,b   Martins, Danyelly Bruneska Gondim ^a   de Araújo, Rosângela Ferreira Frade ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b Pernambuco State Center of Hematology and Hemotherapy   (Brazil)

Author keywords

Acute chest syndrome; CYP2D6; Glutathione S transferase; GSH; GSTs; Hb; HPLC; NADPH; NO; Oxidative stress; PAHs; PCR; SCA; Sickle cell anemia; Stroke; Vaso occlusion

Indexed keywords

GENOMIC DNA; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; HEMOGLOBIN S; LIPID;

ACUTE CHEST SYNDROME; ADULT; ARTICLE; ASEPTIC NECROSIS; CEREBROVASCULAR ACCIDENT; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMUR HEAD NECROSIS; GENE MUTATION; GENETIC POLYMORPHISM; GENOTYPE; HIGH RISK PATIENT; HUMAN; LIPID PEROXIDATION; MAJOR CLINICAL STUDY; MORBIDITY; MULTIPLEX POLYMERASE CHAIN REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RISK FACTOR; SICKLE CELL ANEMIA;

ADULT; ANEMIA, SICKLE CELL; DISEASE PROGRESSION; GENE DELETION; GENETIC ASSOCIATION STUDIES; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; MIDDLE AGED; POLYMORPHISM, GENETIC;

EID: 84878408670     PISSN: 10799796     EISSN: 10960961     Source Type: Journal    
DOI: 10.1016/j.bcmd.2013.03.003     Document Type: Article

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