A comprehensive review on anti-diabetic agents of herbal origin

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 5, Issue SUPPL. 2, 2013, Pages 29-32

  Dixit, Praveen K ^a   Mittal, Suchita ^a  

^a ISI 15   (India)

Author keywords

Blood glucose; Diabetes mellitus; Herbal sources; Insulin

Indexed keywords

ACHYRANTHES ASPERA EXTRACT; ALANINE AMINOTRANSFERASE; ALLOXAN; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; CASEARIA EXTRACT; CASSIA GRANDIS EXTRACT; CATHARANTHUS ROSEUS EXTRACT; CHOLESTEROL; CREATININE; DALBERGIA EXTRACT; FICUS RACEMOSA EXTRACT; GARLIC EXTRACT; GLUCOSE; GUAVA EXTRACT; HERBACEOUS AGENT; METFORMIN; NUTMEG EXTRACT; OLIVE TREE EXTRACT; TERMINALIA CATAPPA EXTRACT; THESPESIA POPULNEA EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA; URIC ACID;

ANTIDIABETIC ACTIVITY; DIABETES MELLITUS; DRUG MEGADOSE; HYPOGLYCEMIA; LOW DRUG DOSE; REVIEW; STREPTOZOCIN DIABETES;

EID: 84878383086     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Review

References (47)

1. Poornima B. Adultration and substitution in herbal drugs a critical analysis. International Journal of Research in Ayurveda & Pharmacy 2010; 1(1): 8-12.
2. Tripathi AK, Bhoyar PK, Baheti JR, Biyani DM, Khalique M, Kothmire MS, Amgaonkar YM, Bhanarkar AB. Herbal Antidiabetics: A Review. Int. J. Res. Pharm. Sci 2011; 2(1): 30-37.
3. Kumar PV, Raidu CS, Atyam VSSSG, Rao AS. Antidiabetic and Hypoglycemic activity of Momordica cymbalaria. International Journal of Pharma World Research 2010; 1(1).
4. Malviya N, Jain S and Malviya S. Antidiabetic potential of medicinal plants. Acta Poloniae Pharmaceutica-Drug Research 2010; 67(2): 113-118.
5. Yasir M, Shrivastava R, Jain P, Das D. Hypoglycemic and Antihyperglycemic Effects of Different Extracts and Combinations of Withania coagulans Dunal and Acacia arabica Lamk in Normal and Alloxan Induced Diabetic Rats. Pharmacognosy Communications 2012; 2(2): 61-66.
6. www.googleimage.com Link-www.zuniv.net.
7. www.googleimage.com Link-www.pathguy.com.
8. Sokeng SD, Lontsi D, Moundipa PF, Jatsa HB, Watcho P and Kamtchouing P. Hypoglycemic Effect of Anacardium occidentale L. Methanol Extract and Fractions on Streptozotocin-induced Diabetic Rats. Global Journal of Pharmacology 2007; 1(1): 01-05.
9. Mujeeb M, Khan SA, Ali M, Mall A and Ahmad A. Antidiabetic activity of the aqueous extract of Annona squamosa in streptozotocin induced-hyperglycemic rats. The Pharma Research 2009; 2; 59-63.
10. Jarald E, Joshi SB, Jain DC. Biochemical study on the hypoglycaemic effects of extract and fraction of Acacia catechu willd in alloxan-induced diabetic rats. Int J Diabetes & Metabolism 2009; 17:63-69.
11. Ozougwu, Jevas C. Anti-diabetic effects of Allium cepa (onions) aqueous extracts on alloxan-induced diabetic Rattus novergicus. Journal of Medicinal Plants Research 2011; 5(7): 1134-1139.
12. Vidhya R, Gandhi GR, Jothi G, Radhika J and Brindha P. Evaluation of antidiabetic potential of Achyranthes aspera Linn. on alloxan Induced diabetic animals. International Journal of Pharmacy and Pharmaceutical Sciences 2012; 4(5): 577-580.
13. Akhtar MS, Iqbal J. Evaluation of the hypoglycaemic effect of Achyranthes aspera in normal and alloxan-diabetic rabbits. J Ethnopharmacol. 1991; 31(1): 49-57.
14. Eidi A, Eidi M, Esmaeili E. Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats. Phytomedicine 2006; 13: 624-629.
15. Saif-Ur-Rehman, Jafri SA, Hassan S, Ahmed I and Naim M. Study on Antidiabetic Effect of Aloe vera Extract on Alloxan Induced Diabetic Rats. Libyan Agriculture Research Center Journal International 2011; 2(1): 29-32.
16. Ahamad J, Mir SR, Naquvi KJ. Hypoglycemic activity of aqueous extract of Berberis aristata stems bark in STZ-induced rats. International Journal of Pharmacy and Pharmaceutical Sciences 2012; 4(2): 473-474.
17. Rathee S, Mogla, OP, Sardana S, Vats M, Rathee P. Antidiabetic activity of Capparis decidua Forsk Edgew. Journal of Pharmacy Research 2010; 3(2): 231.
18. Arula B, Kothai R and Christina AJM. Hypoglycemic Activity of Casearia esculenta Roxb. in Normal and Diabetic Albino Rats. Iranian Journal of Pharmaceutical Research 2006; 1: 47-51.
19. Sangameswaran B and Jayakar B. Anti-diabetic and spermatogenic activity of Cocculus hirsutus (L) Diels. African Journal of Biotechnology 2007; 6(10): 1212-1216.
20. Salahuddin M, Jalalpure SS, Gadge NB. Antidiabetic activity of aqueous bark extract of Cassia glauca in streptozotocin-induced diabetic rats. Canadian Journal of Physiology and Pharmacology 2010; 88(2): 153-160.
21. Surana SJ, Gokhale SB, Jadhav RB, Sawant RL, Wadekar JB. Antihyperglycemic activity of various fractions of Cassia auriculata linn. in alloxan diabetic rats. Indian J Pharm Sci. 2008; 70(2): 227-9.
22. Babu V, Gangadevi T, Subramoniam A. Antidiabetic activity of ethanol extract of Cassia kleinii leaf in streptozotocin-induced diabetic rats and isolation of an active fraction and toxicity evaluation of the extract. Indian Journal of Pharmacology 2003; 35: 290-296.
23. Lodha SR, Joshi SV, Vyas BA, Upadhye MC, Kirve MS, Salunke SS, Kadu SK, Rogye MV. Assessment of the antidiabetic potential of Cassia grandis using an in vivo model. J Adv Pharm Tech Res 2010; 1(3): 330-3.
24. Okokon JE, Bassey AL and Obot J. Antidiabetic activity of ethanolic leaf extract of Croton zambesicus muell. (Thunder plant) in alloxan diabetic rats. Afr. J. Traditional, Complementary and Alternative Medicines 2006; 3(2): 21-26.
25. Ezike AC, Akah PA, Okoli CC and Okpala CB. Experimental evidence for the antidiabetic activity of Cajanus cajan leaves in rats. Journal of Basic and Clinical Pharmacy 2010; 1(2): 81-84.
26. Niranjan PS, Singh D, Prajapati K, Jain SK. Antidiabetic activity of ethanolic extract of Dalbergia sissoo L. leaves in alloxan induced diabetic rats. International Journal of Current Pharmaceutical Research 2010; 2(2): 24-27.
27. Chaturvedi A, Bhawani G, Agarwal PK, Goel S, Singh A and Goel RK. Antidiabetic and antiulcer effects of extract of Eugenia jambolana seed in mild diabetic rats: study on gastric mucosal offensive acid-pepsin secretion. Indian J Physiol Pharmacol 2009; 53(2): 137-146.
28. Nain P, Saini V, and Sharma S. Antidiabetic activity of Emblica officinalis seed extract in streptozotocin induced type-2 diabetes mellitus in rat. International Journal of Natural Product Science 2012; 1: 135.
29. Sharma VK, Kumar S, Patel HJ and Hugar SK. Hypoglycemic activity of Ficus glomerata in alloxan induced diabetic rats. International Journal of Pharmaceutical Sciences Review and Research 2010; 1(2): 18-22.
30. Lakshmi SM, Kumar SA, Srikanth S, Vidyulatha KT, Jyothi G, Choudari DM, Lavanya O. Anti-Diabetic and Antihyperlipidemic Activity of Ficus krishnae L. in Alloxan Induced Diabetic Rats. 2010; 1(1): 14-18.
31. Akah PA, Uzodinma SU and Okolo CE. Antidiabetic activity of aqueous and methanol extract and fractions of Gongronema latifolium (Asclepidaceae) leaves in Alloxan Diabetic Rats. Journal of Applied Pharmaceutical Science 2011; 01(09): 99-102.
32. Minaz N, Rao ANV. Nazeer, Preeth M and Shobana J. Antidiabetic Activity of Hydro-Ethanolic Root Extracts of Ipomoia digitata in Alloxan Induced Diabetic Rats. International Journal of Research in Pharmaceutical and Biomedical Sciences 2010; 1(2): 76-81.
33. Syamsudin, Sumarny R, Simanjuntak P. Antidiabetic Activity of Active Fractions of Leucaena Leucocephala (lmk) Dewit Seeds in Experiment Model. European Journal of Scientific Research 2010; 43(3): 384-391.
34. Somani RS, Singhai AK. Hypoglycaemic and Antidiabetic Activities of Seeds of Myristica fragrans in Normoglycaemic and Alloxan-induced Diabetic Rats. Asian J. Exp. Sci 2008; 22(1): 95-102.
35. Khan MRI, Islam MA, Hossain MS, Asadujjaman M, Wahed MII, Rahman BM, Anisuzzaman ASM, Shaheen SM and Ahmed M. Antidiabetic Effects of the Different Fractions of Ethanolic Extracts of Ocimum sanctum in Normal and Alloxan Induced Diabetic Rats. Journal of Scientific Research 2010; 2(1): 158-168.
36. Chandak RR, Shrangare G. Evaluation of antidiabetic activity of Olea-europea in wistar albino rats. International Journal of Applied Biology and Pharmaceutical Technology 2010; 1(3): 952-956.
37. Thanigaivelan K and Muthukumaran P. Antidiabetic effect of Psidium guajava leaves extract in alloxan induced diabetic rats. International Journal of Recent Scientific Researchm2010; 5: 125-129.
38. Verma PK, Kamboj VK, Mishra MK, Ranjan S. Antidiabetic activity of ethyl acetate extract of Pterocarpus marsupium in alloxan induced diabetic rats. Pharmacologyonline 2011; 3: 730-734.
39. Shetti AA, Sanakal RD and Kaliwal BB. Antidiabetic effect of ethanolic leaf extract of Phyllanthus amarus in alloxan induced diabetic mice. Asian Journal of Plant Science and Research 2012; 2 (1): 11-15.
40. Yadav JP, Saini S, Kalia AN, Dangi AS. Hypoglycemic and hypolipidemic activity of ethanolic extract of Salvadora oleoides in normal and alloxan-induced diabetic rats. Indian Journal of Pharmacology 2008; 40(1): 23-27.
41. Jha RK, Mangilal, Bhandari A, Nema RK. Antidiabetic activity of flower head petroleum ether extracts of Sphaeranthus indicus Linn. Asian Journal of Pharmaceutical and Clinical Research 2010; 3(1): 16-19.
42. Benwahhoud M, Jouad H, Eddouks M, Lyoussi B. Hypoglycemic effect of Suaeda fruticosa in streptozotocin-induced diabetic rats. J Ethnopharmacol. 2001; 76(1): 35-8.
43. Parthasarathy R, Ilavarasan R, Karrunakaran CM. Antidiabetic activity of Thespesia populnea bark and leaf extract against streptozotocin induced diabetic rats. International Journal of Pharm Tech Research 2009; 1(4): 1069-1072.
44. Nagappa AN, Thakurdesai PA, Rao NV, Singh J. Antidiabetic activity of Terminalia catappa Linn fruits. Journal of Ethnopharmacology 2003; 88: 45-50.
45. Mowla A, Alauddin M, Rahman MA and Ahmed K. Antihyperglycemic effect of Trigonella foenum-graecum (fenugreek) seed extract in alloxan-induced diabetic rats and its use in diabetes mellitus: a brief qualitative phytochemical and acute toxicity test on the extract. Afr. J. Traditional, Complementary and Alternative Medicines 2009; 6(3): 255-261.
46. Maiti R, Jana D, Das UK, Ghosh D. Antidiabetic effect of aqueous extract of seed of Tamarindus indica in streptozotocin-induced diabetic rats. J Ethnopharmacol. 2004; 92(1): 85-91.
47. Ahmed MF, Kazim SM, Ghori SS, Ahmed SR, Ali SM and Ibrahim M. Antidiabetic Activity of Vinca rosea Extracts in Alloxan-Induced Diabetic Rats. International Journal of Endocrinology 2010; 1-6.