A study of meiotic segregation in a fertile human population following ovarian stimulation with recombinant FSH-LH

Journal of Assisted Reproduction and Genetics

Volumn 30, Issue 2, 2013, Pages 269-274

  Velilla, Esther ^a   Fernández, Silvia F ^a   Suñol, Jordi ^a   López Teijón, Marisa ^b  

^a Centro Internacional de Medicina Avanzada   (Spain)

^b Instituto Marques   (Spain)

Author keywords

Aneuploidy; Egg donation; IVF; PGD; Polar body analysis

Indexed keywords

RECOMBINANT FOLLITROPIN PLUS RECOMBINANT LUTEINIZING HORMONE;

ANEUPLOIDY; ARTICLE; BIOPSY; CHROMOSOME 13; CHROMOSOME 16; CHROMOSOME 18; CHROMOSOME 21; CHROMOSOME 22; EMBRYO DEVELOPMENT; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE SEGREGATION; HUMAN; NEWBORN; OOCYTE; OVARY STIMULATION; POLAR BODY; PRIORITY JOURNAL; SISTER CHROMATID; STIMULATION; ZYGOTE;

ADULT; CHROMATIDS; CHROMOSOME SEGREGATION; CHROMOSOMES, HUMAN; FEMALE; HUMANS; MEIOSIS; OOCYTE DONATION; OOCYTES; OVULATION INDUCTION; POLAR BODIES; PREGNANCY;

EID: 84878370485     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-012-9905-9     Document Type: Article

References (34)

1. Angell RR, Xian J, Keith J, Ledger W, Baird DT. First meiotic division abnormalities in human oocytes: mechanism of trisomy formation. Cytogenet Cell Genet. 1994;65(3):194-202.
2. Angell RR, Xian J, Keith J. Chromosome anomalies in human oocytes in relation to age. Hum Reprod. 1993;8(7):1047-54.
3. Angell RR. Predivision in human oocytes at meiosis I: a mechanism for trisomy formation in man. Hum Genet. 1991;86(4):383-7.
4. Clyde JM, Gosden RG, Rutherford AJ, Picton HM. Demonstration of a mechanism of aneuploidy in human oocytes using Multifluor fluorescence in situ hybridization. Fertil Steril. 2001;76(4):837-40.
5. Cupisti S, Conn CM, Fragouli E, Whalley K, Mills JA, Faed MJ, et al. Sequential FISH analysis of oocytes and polar bodies reveals aneuploidy mechanisms. Prenat Diagn. 2003;23(8):663-8.
6. Fragouli E, Wells D, Thornhill A, Serhal P, Faed MJ, Harper JC, et al. Comparative genomic hybridization analysis of human oocytes and polar bodies. Hum Reprod. 2006;21(9):2319-28.
7. Fragouli E, Wells D, Whalley KM, Mills JA, Faed MJ, Delhanty JD. Increased susceptibility to maternal aneuploidy demonstrated by comparative genomic hybridization analysis of human MII oocytes and first polar bodies. Cytogenet Genome Res. 2006;114(1):30-8.
8. Fragouli E, Escalona A, Gutierrez-Mateo C, Tormasi S, Alfarawati S, Sepulveda S, et al. Comparative genomic hybridization of oocytes and first polar bodies from young donors. Reprod Biomed Online. 2009;19(2):228-37.
9. Gutiérrez-Mateo C, Benet J, Wells D, Colls P, Bermúdez MG, Sánchez-García JF, et al. Aneuploidy study of human oocytes first polar body comparative genomic hybridization and metaphase II fluorescence in situ hybridization analysis. Hum Reprod. 2004;19(12):2859-68.
10. Gutiérrez-Mateo C, Benet J, Starke H, Oliver-Bonet M, Munné S, Liehr T, et al. Karyotyping of human oocytes by cenMFISH, a new 24-colour centromere-specific technique. Hum Reprod. 2005;20(12):3395-401.
11. Gutiérrez-Mateo C, Wells D, Benet J, Sánchez-García JF, Bermúdez MG, Belil I, et al. Reliability of comparative genomic hybridization to detect chromosome abnormalities in first polar bodies and metaphase II oocytes. Hum Reprod. 2004;19(9):2118-25.
12. Hassold T, Abruzzo M, Adkins K, Griffin D, Merrill M, Millie E, et al. Human aneuploidy: incidence, origin, and etiology. Environ Mol Mutagen. 1996;28(3):167-75. Review.
13. Hassold T, Hunt P. To err (meiotically) is human: the genesis of human aneuploidy. Nat Rev Genet. 2001;2(4):280-91. Review.
14. Hunt P, LeMaire R, Embury P, Sheean L, Mroz K. Analysis of chromosome behavior in intact mammalian oocytes: monitoring the segregation of a univalent chromosome during female meiosis. Hum Mol Genet. 1995;4(11):2007-12.
15. Kamiguchi Y, Rosenbusch B, Sterzik K, Mikamo K. Chromosomal analysis of unfertilized human oocytes prepared by a gradual fixation-air drying method. Hum Genet. 1993;90(5):533-41.
16. Keskintepe L, Sher G, Keskintepe M. Reproductive oocyte/embryo genetic analysis: comparison between fluorescence in-situ hybridization and comparative genomic hybridization. Reprod Biomed Online. 2007;15(3):303-9.
17. Kuliev A, Zlatopolsky Z, Kirillova I, Spivakova J, Cieslak, Janzen J. Meiosis errors in over 20,000 oocytes studied in the practice of preimplantation aneuploidy testing. Reprod Biomed Online. 2011;22(1):2-8.
18. Li Y, Feng HL, Cao YJ, Zheng GJ, Yang Y, Mullen S, et al. Confocal microscopic analysis of the spindle and chromosome configurations of human oocytes matured in vitro. Fertil Steril. 2006;85(4):827-32.
19. Munné S, Ary J, Zouves C, Escudero T, Barnes F, Cinioglu C, et al. Wide range of chromosome abnormalities in the embryos of young egg donors. Reprod Biomed Online. 2006;12(3):340-6.
20. Nicolaidis P, Petersen MB. Origin and mechanisms of non-disjunction in human autosomal trisomies. Hum Reprod. 1998;13(2):313-9. Review.
21. Obradors A, Rius M, Cuzzi J, et al. Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: comparative genomic hybridization analyzes in metaphase II oocytes and their first polar body. Fertil Steril. 2010;93:675-9.
22. Pellestor F, Anahory T, Hamamah S. Effect of maternal age on the frequency of cytogenetic abnormalities in human oocytes. Cytogenet Genome Res. 2005;111(3-4):206-12.
23. Pellestor F, Andréo B, Anahory T, Hamamah S. PRINS as an efficient tool for aneuploidy assessment in human oocytes and preimplantation embryos. Methods Mol Biol. 2006;334:151-60.
24. Pellestor F, Andréo B, Arnal F, Humeau C, Demaille J. Maternal aging and chromosomal abnormalities: new data drawn from in vitro unfertilized human oocytes. Hum Genet. 2003;112(2):195-203.
25. Reis Soares S, Rubio C, Rodrigo L, Simón C, Remohí J, Pellicer A. High frequency of chromosomal abnormalities in embryos obtained from oocyte donation cycles. Fertil Steril. 2003;80(3):656-7.
26. Requena A, Bronet F, Guillen A, Agudo D, Bou C, García-Velasco JA. The impact of in-vitro maturation of oocytes on aneuploidy rate. Reprod Biomed Online. 2009;18(6):777-83.
27. Sandalinas M, Márquez C, Munné S. Spectral karyotyping of fresh, non-inseminated oocytes. Mol Hum Reprod. 2002;8(6):580-5.
28. Sher G, Keskintepe L, Keskintepe M, et al. Oocyte karyotyping by comparative genomic hybridization [correction of hybrydization] provides a highly reliable method for selecting 'competent' embryos, markedly improving in vitro fertilization outcome: a multiphase study. Fertil Steril. 2007;87:1033-40.
29. Verlinsky Y, Cieslak J, Ivakhnenko V, Evsikov S, Wolf G, White M, et al. Chromosomal abnormalities in the first and second polar body. Mol Cell Endocrinol. 2001;183 Suppl 1:S47-9.
30. Verlinsky Y, Cieslak J, Ivakhnenko V, Evsikov S, Wolf G, White M, et al. Prevention of age-related aneuploidies by polar body testing of oocytes. J Assist Reprod Genet. 1999;16(4):165-9.
31. Verlinsky Y, Kuliev A. Atlas of preimplantation genetic diagnosis. Second edition. Taylor and Francis Group. 2005.
32. Verlinsky Y, Lerner S, Illkevitch N, Kuznetsov V, Kuznetsov I, Cieslak J, et al. Is there any predictive value of first polar body morphology for embryo genotype or developmental potential? Reprod Biomed Online. 2003;7(3):336-41.
33. Vlaisavljevic V, Krizancic Bombek L, Vokac NK, Kovacic B, Cizek-Sajko M. How safe is germinal vesicle stage oocyte rescue? Aneuploidy analysis of in vitro matured oocytes. Eur J Obstet Gynecol Reprod Biol. 2007;134(2):213-9.
34. Zenzes MT, Casper RF. Cytogenetics of human oocytes, zygotes, and embryos after in vitro fertilization. Hum Genet. 1992;88(4):367-75. Review.