Comparative efficiency of microbial enzyme preparations versus pancreatin for in vitro alimentary protein digestion

Amino Acids

Volumn 44, Issue 2, 2013, Pages 563-572

  Andriamihaja, Mireille ^a   Guillot, Alain ^b   Svendsen, Allan ^c   Hagedorn, Joerg ^d   Rakotondratohanina, Sahondra ^a   Tomé, Daniel ^a   Blachier, François ^a  

^a INRA Institut National de la Recherche Agronomique   (France)

^b UMR1319 MICALIS   (France)

^c NOVOZYMES A S   (Denmark)

^d ABBOTT GMBH AND CO KG   (Germany)

Author keywords

Digestion; Microbial enzymes; Pancreatin; Proteins

Indexed keywords

CASEIN; MICROBIAL ENZYME; NONSTRUCTURAL PROTEIN 4; NONSTRUCTURAL PROTEIN 5; PANCREATIN; SOYBEAN PROTEIN;

AMINO ACID ANALYSIS; ARTICLE; BACILLUS SUBTILIS; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFICACY; DRUG RESPONSE; ENZYME ACTIVITY; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; NOCARDIOPSACEAE; NOCARDIOPSIS PRASINA; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN METABOLISM; TANDEM MASS SPECTROMETRY;

ACTINOMYCETALES; ANIMALS; BACILLUS SUBTILIS; BACTERIAL PROTEINS; CASEINS; DIGESTION; HYDROGEN-ION CONCENTRATION; KINETICS; PANCREATIN; PEPTIDE HYDROLASES; SOYBEAN PROTEINS; SWINE;

SUIDAE;

EID: 84878366390     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-012-1373-0     Document Type: Article

References (23)

1. Bruno MJ, Borm JJ, Hoek FJ, Delzenne B, Hofmann AF, de Goeij JJ, van Royen EA, van Leeuwen DJ, Tytgat GN (1998) Gastric transit and pharmacodynamics of a two-millimeter enteric-coated pancreatin microsphere preparation in patients with chronic pancreatitis. Dig Dis Sci 43(1):203-213
2. DiMagno EP, Go VL, Summerskill WH (1973) Relations between pancreatic enzyme ouputs and malabsorption in severe pancreatic insufficiency. N Engl J Med 288(16):813-815
3. Dominguez-Munoz JE, Birckelbach U, Glasbrenner B, Sauerbruch T, Malfertheiner P (1997) Effect of oral pancreatic enzyme administration on digestive function in healthy subjects: comparison between two enzyme preparations. Aliment Pharmacol Ther 11(2):403-408
4. Halm U, Loser C, Lohr M, Katschinski M, Mossner J (1999) A double-blind, randomized, multicentre, crossover study to prove equivalence of pancreatin minimicrospheres versus microspheres in exocrine pancreatic insufficiency. Aliment Pharmacol Ther 13(7):951-957
5. Ioannidis O, Lavrentieva A, Botsios D (2008) Nutrition support in acute pancreatitis. JOP.J. Pancreas 9:375-390
6. Lankisch PG, Lembcke B, Wemken G, Creutzfeldt W (1986) Functional reserve capacity of the exocrine pancreas. Digestion 35(3):175-181
7. Lauwers A, Ruyssen R (1968) Determination of trypsin, chymotrypsin and elastase in pancreatin. J Pharm Belg 23(5):295-306
8. Layer P, Groger G (1993) Fate of pancreatic enzymes in the human intestinal lumen in health and pancreatic insufficiency. Digestion 54(Suppl 2):10-14
9. Layer P, Keller J (1999) Pancreatic enzymes: secretion and luminal nutrient digestion in health and disease. J Clin Gastroenterol 28(1):3-10
10. Layer P, Keller J (2003) Lipase supplementation therapy: standards, alternatives, and perspectives. Pancreas 26(1):1-7
11. Layer P, Keller J, Lankisch PG (2001) Pancreatic enzyme replacement therapy. Curr Gastroenterol Rep 3(2):101-108
12. Li X, Rezaei R, Li P, Wu G (2011) Composition of amino acids in feed ingredients for animal diets. Amino Acids 40(4):1159-1168
13. Littlewood JM, Connett GJ, Sander-Struckmeier S, Henniges F, Creon 40,000 Study Group (2011) A 2-year post-authorisation safety study of high-strength pancreatic enzyme replacement therapy (pancreatin 40,000) in cystic fibrosis. Expert Opin Drug Saf 10(2):197-203
14. Lohr JM, Hummel FM, Pirilis KT, Steinkamp G, Korner A, Henniges F (2009) Properties of different pancreatin preparations used in pancreatic exocrine insufficiency. Eur J Gastroenterol Hepatol 21(9):1024-1031
15. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193(1):265-275
16. Meier RF, Beglinger C (2006) Nutrition in pancreatic diseases. Best Pract Res Clin Gastroenterol 20(3):507-529
17. Nedkov P, Oberthur W, Braunitzer G (1983) Primary structure of subtilisin DY. Hoppe Seylers Z Physiol Chem 364(11):1537-1540
18. Savoie L, Agudelo RA, Gauthier SF, Marin J, Pouliot Y (2005) In vitro determination of the release kinetics of peptides and free amino acids during the digestion of food proteins. J AOAC Int 88(3):935-948
19. Sikkens EC, Cahen DL, Kuipers EJ, Bruno MJ (2010) Pancreatic enzyme replacement therapy in chronic pancreatitis. Best Pract Res Clin Gastroenterol 24(3):337-347
20. Valette P, Malouin H, Corring T, Savoie L (1993) Impact of exocrine pancreatic adaptation on in vitro protein digestibility. Br J Nutr 69(2):359-369
21. Van Hoozen CM, Peeke PG, Taubeneck M, Frey CF, Halsted CH (1997) Efficacy of enzyme supplementation after surgery for chronic pancreatitis. Pancreas 14(2):174-180
22. Whitcomb DC, Lowe ME (2007) Human pancreatic digestive enzymes. Dig Dis Sci 52(1):1-17
23. Zellner M, Winkler W, Hayden H, Diestinger M, Eliasen M, Gesslbauer B, Miller I, Chang M, Kungl A, Roth E, Oehler R (2005) Quantitative validation of different protein precipitation methods in proteome analysis of blood platelet. Electrophoresis 26:2481-2489