Low-dose temozolomide before dendritic-cell vaccination reduces (specifically) CD4+CD25++Foxp3+ regulatory T-cells in advanced melanoma patients

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Ridolfi, Laura ^a   Petrini, Massimiliano ^a   Granato, Anna Maria ^a   Gentilcore, Giusy ^b   Simeone, Ester ^b   Ascierto, Paolo Antonio ^b   Pancisi, Elena ^a   Ancarani, Valentina ^a   Fiammenghi, Laura ^a   Guidoboni, Massimo ^a   de Rosa, Francesco ^a   Valmorri, Linda ^a   Scarpi, Emanuela ^a   Nicoletti, Stefania Vittoria Luisa ^a   Baravelli, Stefano ^c   Riccobon, Angela ^a   Ridolfi, Ruggero ^a  

^a DEPARTMENT OF MEDICAL ONCOLOGY   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c MORGAGNI PIERANTONI HOSPITAL   (Italy)

Author keywords

Dendritic cell; Foxp3+Tregs; Low dose temozolomide; Melanoma; Vaccine

Indexed keywords

HEMOCYANIN; INTERLEUKIN 2; TEMOZOLOMIDE; TRANSCRIPTION FACTOR FOXP3;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER IMMUNIZATION; CANCER IMMUNOTHERAPY; CANCER SURVIVAL; CD4+ CD25+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE CONTROL; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; FEMALE; FLOW CYTOMETRY; HUMAN; LOW DRUG DOSE; LYMPHOCYTE COUNT; MALE; MELANOMA; OVERALL SURVIVAL; REGULATORY T LYMPHOCYTE;

ADULT; AGED; CANCER VACCINES; CTLA-4 ANTIGEN; DACARBAZINE; DENDRITIC CELLS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HEMOCYANIN; HUMANS; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MALE; MELANOMA; MIDDLE AGED; T-LYMPHOCYTES, REGULATORY; TREATMENT OUTCOME;

EID: 84878359155     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-135     Document Type: Article

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