The drug efflux pump Pgp1 in pro-inflammatory lymphocytes is a target for novel treatment strategies in COPD

Respiratory Research

Volumn 14, Issue 1, 2013, Pages

  Hodge, Greg ^a,b   Holmes, Mark ^a,b   Jersmann, Hubertus ^a,b   Reynolds, Paul N ^a,b   Hodge, Sandra ^a,b  

^a ROYAL ADELAIDE HOSPITAL   (United States)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

COPD; Granzyme B; Pgp1; Pro inflammatory lymphocytes

Indexed keywords

CALCEIN; CYCLOSPORIN A; GAMMA INTERFERON; GRANZYME B; METHYLPREDNISOLONE; MULTIDRUG RESISTANCE PROTEIN 1; PREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; CYCLOSPORIN; CYTOKINE; GRANZYME; MULTIDRUG RESISTANCE PROTEIN;

ADULT; ARTICLE; BLOOD SAMPLING; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CELL STIMULATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; CYTOKINE PRODUCTION; DRUG EFFECT; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NATURAL KILLER CELL; NATURAL KILLER T CELL; PROTEIN EXPRESSION; AGED; BIOSYNTHESIS; COMPLICATION; CYTOTOXIC T LYMPHOCYTE; DRUG EFFECTS; INFLAMMATION; LEUKOCYTE COUNT; LYMPHOCYTE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

AGED; ANTI-INFLAMMATORY AGENTS; CYCLOSPORINE; CYTOKINES; FEMALE; GRANZYMES; HUMANS; INFLAMMATION; LEUKOCYTE COUNT; LYMPHOCYTES; MALE; METHYLPREDNISOLONE; MIDDLE AGED; P-GLYCOPROTEIN; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84878345468     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-14-63     Document Type: Article

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