Phase II clinical trial of cediranib in patients with metastatic castration-resistant prostate cancer

BJU International

Volumn 111, Issue 8, 2013, Pages 1269-1280

  Dahut, William L ^a   Madan, Ravi A ^a   Karakunnel, Joyson J ^a   Adelberg, David ^a   Gulley, James L ^a   Turkbey, Ismail B ^a   Chau, Cindy H ^a   Spencer, Shawn D ^b   Mulquin, Marcia ^a   Wright, John ^a   Parnes, Howard L ^a   Steinberg, Seth M ^a   Choyke, Peter L ^a   Figg, William D ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

angiogenesis inhibitors; AZD2171; castration resistant prostate cancer; cediranib

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; BISPHOSPHONIC ACID DERIVATIVE; CEDIRANIB; DOCETAXEL; GADOLINIUM; HEMOGLOBIN; PREDNISONE; TRASTUZUMAB;

ADULT; AGED; ANEMIA; ANOREXIA; ARTICLE; BLOOD TOXICITY; BLOOD VESSEL PERMEABILITY; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER SURVIVAL; CASTRATION RESISTANT PROSTATE CANCER; CENTRAL NERVOUS SYSTEM DISEASE; CENTRAL NERVOUS SYSTEM HEMORRHAGE; CHEMOTHERAPY INDUCED EMESIS; COHORT ANALYSIS; CONTRAST ENHANCEMENT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEHYDRATION; DIARRHEA; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG SAFETY; DRUG TUMOR LEVEL; DRUG WITHDRAWAL; EMBOLISM; FATIGUE; HUMAN; HYPERBILIRUBINEMIA; HYPERTENSION; HYPOALBUMINEMIA; HYPOKALEMIA; HYPONATREMIA; HYPOTHYROIDISM; HYPOXIA; KIDNEY FAILURE; LYMPHOCYTOPENIA; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; MULTIPLE CYCLE TREATMENT; MUSCLE WEAKNESS; NAUSEA; NUCLEAR MAGNETIC RESONANCE IMAGING; OPEN STUDY; OVERALL SURVIVAL; PAIN; PARTIAL THROMBOPLASTIN TIME; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEINURIA; QT PROLONGATION; SIDE EFFECT; SURVIVAL TIME; THROMBOCYTE; THROMBOSIS; TREATMENT RESPONSE; WEIGHT REDUCTION;

ADENOCARCINOMA; ADMINISTRATION, ORAL; AGED; DOSE-RESPONSE RELATIONSHIP, DRUG; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEOPLASM METASTASIS; ORCHIECTOMY; PROSTATIC NEOPLASMS; PROTEIN KINASE INHIBITORS; QUINAZOLINES; TIME FACTORS; TREATMENT OUTCOME;

EID: 84878337994     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2012.11667.x     Document Type: Article

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