Atypical chemokine receptor D6 inhibits human non-small cell lung cancer growth by sequestration of chemokines

Oncology Letters

Volumn 6, Issue 1, 2013, Pages 91-95

  Wu, Feng Ying ^a   Fan, Jiang ^a   Tang, Liang ^a   Zhao, Yin Min ^a   Zhou, Cai Cun ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Chemokines; D6; Decoy receptor; Lung neoplasm; Proliferation

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR D6; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; GROWTH CURVE; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; LUNG SEQUESTRATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING;

EID: 84878332102     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2013.1358     Document Type: Article

References (21)

1. Mantovani A, Savino B, Locati M, Zammataro L, Allavena P and Bonecchi R: The chemokine system in cancer biology and therapy. Cytokine Growth Factor Rev 21: 27-39, 2010.
2. Zlotnik A: Chemokines and cancer. Int J Cancer 119: 2026-2029, 2006.
3. Ben-Baruch A: The multifaceted roles of chemokines in malignancy. Cancer Metastasis Rev 25: 357-371, 2006.
4. Comerford I, Litchfield W, Harata-Lee Y, Nibbs RJ and McColl SR: Regulation of chemotactic networks by 'atypical' receptors. Bioessays 29: 237-247, 2007.
5. Feng LY, Ou ZL, Wu FY, Shen ZZ and Shao ZM: Involvement of a novel chemokine decoy receptor CCX-CKR in breast cancer growth, metastasis and patient survival. Clin Cancer Res 15: 2962-2970, 2009.
6. Wang J, Ou ZL, Hou YF, et al: Enhanced expression of Duffy antigen receptor for chemokines by breast cancer cells attenuates growth and metastasis potential. Oncogene 25: 7201-7211, 2006.
7. Wu FY, Ou ZL, Feng LY, et al: Chemokine decoy receptor d6 plays a negative role in human breast cancer. Mol Cancer Res 6: 1276-1288, 2008.
8. Addison CL, Belperio JA, Burdick MD and Strieter RM: Overexpression of the duffy antigen receptor for chemokines (DARC) by NSCLC tumor cells results in increased tumor necrosis. BMC Cancer 4: 28, 2004.
9. Ramezani A and Hawley RG: Overview of the HIV-1 Lentiviral Vector System. Curr Protoc Mol Biol Chapter 16: Unit 16.21, 2002.
10. Kruizinga RC, Bestebroer J, Berghuis P, et al: Role of chemokines and their receptors in cancer. Curr Pharm Des 15: 3396-3416, 2009.
11. Wong D and Korz W: Translating an Antagonist of Chemokine Receptor CXCR4: from bench to bedside. Clin Cancer Res 14: 7975-7980, 2008.
12. Graham GJ and McKimmie CS: Chemokine scavenging by D6: a movable feast? Trends Immunol 27: 381-386, 2006.
13. Locati M, Torre YM, Galliera E, et al: Silent chemoattractant receptors: D6 as a decoy and scavenger receptor for inflammatory CC chemokines. Cytokine Growth Factor Rev 16: 679-686, 2005.
14. Nibbs RJ, Gilchrist DS, King V, et al: The atypical chemokine receptor D6 suppresses the development of chemically induced skin tumors. J Clin Invest 117: 1884-1892, 2007.
15. Loberg RD, Day LL, Harwood J, et al: CCL2 is a potent regulator of prostate cancer cell migration and proliferation. Neoplasia 8: 578-586, 2006.
16. Lu Y, Cai Z, Galson DL, et al: Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion. Prostate 66: 1311-1318, 2006.
17. Roca H, Varsos Z and Pienta KJ: CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation. J Biol Chem 283: 25057-25073, 2008.
18. Ek S, Björck E, Högerkorp CM, et al: Mantle cell lymphomas acquire increased expression of CCL4, CCL5 and 4-1BB-L implicated in cell survival. Int J Cancer 118: 2092-2097, 2006.
19. Murooka TT, Rahbar R and Fish EN: CCL5 promotes proliferation of MCF-7 cells through mTOR-dependent mRNA translation. Biochem Biophys Res Commun 387: 381-386, 2009.
20. Barbieri F, Bajetto A, Stumm R, et al: Overexpression of stromal cell-derived factor 1 and its receptor CXCR4 induces autocrine/paracrine cell proliferation in human pituitary adenomas. Clin Cancer Res 14: 5022-5032, 2008.
21. Singh RK and Lokeshwar BL: Depletion of intrinsic expression of Interleukin-8 in prostate cancer cells causes cell cycle arrest, spontaneous apoptosis and increases the efficacy of chemotherapeutic drugs. Mol Cancer 8: 57, 2009.