Effects of solutol (Kolliphor) and cremophor in polyethylene glycol 400 vehicle formulations in sprague-dawley rats and beagle dogs

International Journal of Toxicology

Volumn 32, Issue 3, 2013, Pages 189-197

  Stokes, Alan H ^a   Kemp, Daniel C ^a   Faiola, Brenda ^a,b   Jordan, Holly L ^a   Merrill, Christine L ^a   Hailey, James R ^a   Brown, Randy E ^a   Bailey, David W ^a  

^a GLAXOSMITHKLINE   (United States)

^b ICON PLC   (United Kingdom)

Author keywords

beagle dogs; Cremophor; Kolliphor; Solutol; Sprague Dawley

Indexed keywords

ALANINE AMINOTRANSFERASE; CHOLESTEROL; CREATININE; CREMOPHOR; GLUCOSE; MACROGOL 400; PHOSPHORUS; SOLUTOL HS 15; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE URINE LEVEL; ELECTROLYTE BLOOD LEVEL; ELECTROLYTE URINE LEVEL; EXPERIMENTAL DOG; FECES; FEMALE; GLUCOSE URINE LEVEL; HEART WEIGHT; HEMATOCRIT; HEMOCONCENTRATION; ILEUM; INCIDENCE; KIDNEY MASS; MALE; NONHUMAN; RAT; RELATIVE DENSITY; SOLUBILIZATION; STOMACH HEMORRHAGE; THYMUS; UREA BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL; URINE VOLUME; VISCOSITY; VOMITING;

BEAGLE DOGS; CREMOPHOR; KOLLIPHOR; SOLUTOL; SPRAGUE-DAWLEY;

ANIMALS; DOGS; FEMALE; MALE; POLYETHYLENE GLYCOLS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SPECIFIC PATHOGEN-FREE ORGANISMS; STEARIC ACIDS;

CANIS FAMILIARIS; RATTUS; RODENTIA;

EID: 84878330825     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581813485452     Document Type: Article

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