Systemic toxicity and toxicokinetics of a high dose of polyethylene glycol 400 in dogs following intravenous injection

Drug and Chemical Toxicology

Volumn 34, Issue 2, 2011, Pages 208-212

  Li, Bao Qiu ^a   Dong, Xin ^b   Fang, Shi Hong ^b   Gao, Ji You ^b   Yang, Gui Qin ^b   Zhao, Hua ^b  

^a SHANDONG UNIVERSITY   (China)

^b Shandong Hongli Laboratory Animal Experiment Co Ltd   (China)

Author keywords

pharmaceutical excipient; Polyethylene glycol 400; toxicity; toxicokinetics

Indexed keywords

MACROGOL 400;

ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DOG; DRUG MEGADOSE; DRY NASAL MUCUS MEMBRANE; ELECTROCARDIOGRAM; FEMALE; HISTOPATHOLOGY; MALE; NONHUMAN; NOSE DISEASE; NOSE MUCUS; TOXICOKINETICS; XEROSTOMIA;

ANIMALS; AREA UNDER CURVE; CLINICAL CHEMISTRY TESTS; DOGS; DRUG CARRIERS; FEMALE; HEMATOLOGIC TESTS; INJECTIONS, INTRAVENOUS; KIDNEY; KIDNEY GLOMERULUS; MALE; POLYETHYLENE GLYCOLS; TOXICITY TESTS;

ANIMALIA; CANIS FAMILIARIS;

EID: 79951631713     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480545.2010.500292     Document Type: Article

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