Protection of glycyrrhizic acid against AGEs-induced endothelial dysfunction through inhibiting RAGE/NF-κB pathway activation in human umbilical vein endothelial cells

Journal of Ethnopharmacology

Volumn 148, Issue 1, 2013, Pages 27-36

  Feng, Liang ^a   Zhu, Mao Mao ^a   Zhang, Ming Hua ^a   Wang, Ru Shang ^b   Tan, Xiao Bin ^a   Song, Jie ^a   Ding, Shu Min ^a,c   Jia, Xiao Bin ^a   Hu, Shao Ying ^a  

^a KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

^b Institute of Conson Co for Chinese Medicine in Kidiney Diseases   (China)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

AGEs; Apoptosis; Endothelial dysfunction; Inflammation; Oxidant stress; RAGE

Indexed keywords

ADVANCED GLYCATION END PRODUCT; GLYCYRRHIZIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALONALDEHYDE; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; IN VITRO STUDY; OXIDATIVE STRESS; PROTEIN EXPRESSION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WESTERN BLOTTING;

ANTI-INFLAMMATORY AGENTS; ANTIGENS, NEOPLASM; ANTIOXIDANTS; APOPTOSIS; CELLS, CULTURED; GLYCOSYLATION END PRODUCTS, ADVANCED; GLYCYRRHIZIC ACID; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALONDIALDEHYDE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

GLYCYRRHIZA; GLYCYRRHIZA URALENSIS;

EID: 84878330394     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.03.035     Document Type: Article

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