Clinical outcomes of fast MRI-based trombolysis in wake-up strokes compared to superacute ischemic strokes within 12 hours

Neurological Research

Volumn 35, Issue 5, 2013, Pages 492-497

  Bai, Qingke ^a   Zhao, Zhenguo ^a   Fu, Paul ^b   Sui, Haijing ^a   Xie, Xiuhai ^a   Chen, Juan ^a   Yang, Juan ^a  

^a People's Hospital of Pudong District   (China)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute ischemic stroke; Magnetic resonance imaging; Thrombolysis; Wake Up Ischemic Strokes

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

ADULT; ARTICLE; BARTHEL INDEX; BLOOD CLOT LYSIS; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; COMPUTER ASSISTED TOMOGRAPHY; DIFFUSION WEIGHTED IMAGING; FEMALE; FIBRINOLYTIC THERAPY; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MORTALITY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NUCLEAR MAGNETIC RESONANCE IMAGING; RANKIN SCALE; SCORING SYSTEM; STENOSIS; THROMBOCYTE COUNT; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; EARLY DIAGNOSIS; FEMALE; FIBRINOLYTIC AGENTS; HEMORRHAGE; HUMANS; MALE; MIDDLE AGED; NEUROIMAGING; STROKE; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME;

EID: 84878318304     PISSN: 01616412     EISSN: 17431328     Source Type: Journal    
DOI: 10.1179/1743132813Y.0000000208     Document Type: Article

References (18)

1. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. 1995;333:1581-7.
2. Generalized efficacy of t-PA for acute stroke. Subgroup analysis of the NINDS t-PA Stroke Trial. Stroke. 28:2119-25.
3. Hacke W, Kaste M, Bluhmki E, Brozman M, Davalos A, Guidetti D, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008;359:1317-29.
4. Fink JN, Kumar S, Horkan C, Linfante I, Selim MH, Caplan LR, et al. The stroke patient who woke up: clinical and radiological features, including diffusion and perfusion MRI. Stroke. 2002;33:988-93.
5. Serena J, Davalos A, Segura T, Mostacero E, Castillo J. Stroke on awakening: looking for a more rational management. Cerebrovasc Dis. 2003;16:128-33.
6. Barreto AD, Martin-Schild S, Hallevi H, Morales MM, Abraham AT, Gonzales NR, et al. Thrombolytic therapy for patients who wake-up with stroke. Stroke. 2009;40:827-32.
7. Aoki J, Kimura K, Iguchi Y, Shibazaki K, Iwanaga T, Watanabe M, et al. Intravenous thrombolysis based on diffusion-weighted imaging and fluid-attenuated inversion recovery mismatch in acute stroke patients with unknown onset time. Cerebrovasc Dis. 2011;31:435-41.
8. Campbell BC, Purushotham A, Christensen S, Desmond PM, Nagakane Y, Parsons MW, et al. The infarct core is well represented by the acute diffusion lesion: sustained reversal is infrequent. J Cereb Blood Flow Metab. 2012;32:50-6.
9. Deguchi I, Takeda H, Furuya D, Hattori K, Dembo T, Nagoya H, et al. Significance of clinical-diffusion mismatch in hyperacute cerebral infarction. J Stroke Cerebrovasc Dis. 2011;20:62-7.
10. Kruetzelmann A, Kohrmann M, Sobesky J, Cheng B, Rosenkranz M, Röther J, et al. Pretreatment diffusionweighted imaging lesion volume predicts favorable outcome after intravenous thrombolysis with tissue-type plasminogen activator in acute ischemic stroke. Stroke. 2011;42:1251-4.
11. Seitz RJ, Oberstrass H, Ringelstein A, Wittsack HJ, Siebler M. Failed recovery from thrombolysis is predicted by the initial diffusion weighted imaging lesion. Cerebrovasc Dis. 2011;31:580-7.
12. Tisserand M, Le Guennec L, Touze E, Hess A, Charbonnier C, Devauchelle AD, et al. Prevalence of MRI-defined recent silent ischemia and associated bleeding risk with thrombolysis. Neurology. 2011;76:1288-95.
13. Bai Q, Zhao Z, Li Y, Sui H, Xie X, Gong Y, et al. The application of fast multiparametric protocol MRI-based thrombolysis with rt-PA hyperacute cerebral infarction. Neurol Res. 2008;30:344-7.
14. Zhao Z, Bai Q, Sui H, Xie X, Wen F. Fast multimode MRI based emergency assessment of hyperacute stroke thrombolysis. Neurol Res. 2009;31:346-50.
15. Li YH, Li MH, Zhao ZG, Bai QK. Comparison of MRIbased thrombolysis for patients with middle cerebral artery occlusion, or53 h and 3-6 h. Neurol India. 2009;57:426-33.
16. Shobha N, Buchan AM, Hill MD. Thrombolysis at 3-4.5 hours after acute ischemic stroke onset-evidence from the Canadian Alteplase for Stroke Effectiveness Study (CASES) registry. Cerebrovasc Dis. 2011;31:223-8.
17. Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010;375:1695-703.
18. Yamaguchi T, Mori E, Minematsu K, Nakagawara J, Hashi K, Saito I, et al. Alteplase at 0.6 mg/kg for acute ischemic stroke within 3 hours of onset: Japan Alteplase Clinical Trial (J-ACT). Stroke. 2006;37:1810-5.