Intravenous thrombolysis based on diffusion-weighted imaging and fluid-attenuated inversion recovery mismatch in acute stroke patients with unknown onset time

Cerebrovascular Diseases

Volumn 31, Issue 5, 2011, Pages 435-441

  Aoki, Junya ^a   Kimura, Kazumi ^a   Iguchi, Yasuyuki ^a   Shibazaki, Kensaku ^a   Iwanaga, Takeshi ^a   Watanabe, Masao ^a   Kobayashi, Kazuto ^a   Sakai, Kenichiro ^a   Sakamoto, Yuki ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

Acute ischemic stroke, unknown onset time; Magnetic resonance imaging; Thrombolytic therapy

Indexed keywords

ALTEPLASE;

ACUTE STROKE; ADULT; AGED; APHASIA; ARTICLE; BRAIN HEMORRHAGE; CLINICAL ARTICLE; CLINICAL TRIAL; CONSCIOUSNESS DISORDER; CONTINUOUS INFUSION; CONVALESCENCE; DIFFUSION WEIGHTED IMAGING; DISEASE COURSE; DRUG SAFETY; FEMALE; FIBRINOLYTIC THERAPY; FLUID ATTENUATED INVERSION RECOVERY; HUMAN; IMAGE ANALYSIS; INTERNAL CAROTID ARTERY OCCLUSION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; PRIORITY JOURNAL; RANKIN SCALE; SINGLE DRUG DOSE; SLEEP; STROKE; UNKNOWN ONSET TIME;

AGED; AGED, 80 AND OVER; ATRIAL FIBRILLATION; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MIDDLE AGED; NERVOUS SYSTEM DISEASES; RISK FACTORS; SOCIOECONOMIC FACTORS; STROKE; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME;

EID: 79951851412     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000323850     Document Type: Article

References (22)

1. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med 1995; 333: 1581-1587.
2. Fink JN, Kumar S, Horkan C, Linfante I, Selim MH, Caplan LR, Schlaug G: The stroke patient who woke up: clinical and radiological features, including diffusion and perfusion MRI. Stroke 2002; 33: 988-993. (Pubitemid 34293580)
3. Iosif C, Oppenheim C, Trystram D, Domigo V, Meder JF: MR imaging-based decision in thrombolytic therapy for stroke on awakening: report of 2 cases. AJNR Am J Neuroradiol 2008; 29: 1314-1316.
4. Barreto AD, Martin-Schild S, Hallevi H, Morales MM, Abraham AT, Gonzales NR, Illoh K, Grotta JC, Savitz SI: Thrombolytic therapy for patients who wake-up with stroke. Stroke 2009; 40: 827-832.
5. Cho AH, Sohn SI, Han MK, Lee DH, Kim JS, Choi CG, Sohn CH, Kwon SU, Suh DC, Kim SJ, Bae HJ, Kang DW: Safety and efficacy of MRI-based thrombolysis in unclear-onset stroke. A preliminary report. Cerebrovasc Dis 2008; 25: 572-579. (Pubitemid 351861477)
6. Davis SM, Donnan GA, Parsons MW, Levi C, Butcher KS, Peeters A, Barber PA, Bladin C, De Silva DA, Byrnes G, Chalk JB, Fink JN, Kimber TE, Schultz D, Hand PJ, Frayne J, Hankey G, Muir K, Gerraty R, Tress BM, Desmond PM: Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol 2008; 7: 299-309.
7. Thomalla G, Rossbach P, Rosenkranz M, Siemonsen S, Krutzelmann A, Fiehler J, Gerloff C: Negative fluid-attenuated inversion recovery imaging identifies acute ischemic stroke at 3 h or less. Ann Neurol 2009; 65: 724-732.
8. Kimura K, Iguchi Y, Shibazaki K, Terasawa Y, Inoue T, Uemura J, Aoki J: Large ischemic lesions on diffusion-weighted imaging done before intravenous tissue plasminogen activator thrombolysis predicts a poor outcome in patients with acute stroke. Stroke 2008; 39: 2388-2391.
9. Yamaguchi T, Mori E, Minematsu K, Nakagawara J, Hashi K, Saito I, Shinohara Y: Alteplase at 0.6 mg/kg for acute ischemic stroke within 3 hours of onset: Japan Alteplase Clinical Trial (J-ACT). Stroke 2006; 37: 1810-1815. (Pubitemid 44297734)
10. Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE 3rd: Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993; 24: 35-41. (Pubitemid 23014379)
11. Toyoda K, Ida M, Fukuda K: Fluid-attenuated inversion recovery intraarterial signal: an early sign of hyperacute cerebral ischemia.AJNR Am J Neuroradiol 2001; 22: 1021-1029. (Pubitemid 32587411)
12. Aoki J, Kimura K, Iguchi Y, Shibazaki K, Sakai K, Iwanaga T: FLAIR can estimate the onset time in acute ischemic stroke patients.J Neurol Sci 2010; 293: 39-44.
13. Kimura K, Iguchi Y, Shibazaki K, Aoki J, Terasawa Y: Hemorrhagic transformation of ischemic brain tissue after t-PA thrombolysis as detected by MRI may be asymptomatic, but impair neurological recovery. J Neurol Sci 2008; 272: 136-142.
14. Kimura K, Iguchi Y, Shibazaki K, Iwanaga T, Yamashita S, Aoki J: IV t-PA therapy in acute stroke patients with atrial fibrillation. J Neurol Sci 2009; 276: 6-8.
15. Chalela JA, Kidwell CS, Nentwich LM, Luby M, Butman JA, Demchuk AM, Hill MD, Patronas N, Latour L, Warach S: Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison.Lancet 2007; 369: 293-298. (Pubitemid 46136489)
16. Noguchi K, Ogawa T, Inugami A, Fujita H, Hatazawa J, Shimosegawa E, Okudera T, Uemura K, Seto H: MRI of acute cerebral infarction: a comparison of FLAIR and T 2 - weighted fast spin-echo imaging. Neuroradiology 1997; 39: 406-410. (Pubitemid 27252606)
17. Cho AH, Kim JS, Kim SJ, Yun SC, Choi CG, Kim HR, Kwon SU, Lee DH, Kim EK, Suh DC, Kang DW: Focal fluid-attenuated inversion recovery hyperintensity within acute diffusion-weighted imaging lesions is associated with symptomatic intracerebral hemorrhage after thrombolysis. Stroke 2008; 39: 3424-3426.
18. Kleindorfer D, Lindsell CJ, Brass L, Koroshetz W, Broderick JP: National US estimates of recombinant tissue plasminogen activator use: ICD-9 codes substantially underestimate.Stroke 2008; 39: 924-928. (Pubitemid 351619542)
19. Ebinger M, Galinovic I, Rozanski M, Brunecker P, Endres M, Fiebach JB: Fluid-attenuated inversion recovery evolution within 12 hours from stroke onset: a reliable tissue clock? Stroke 2010; 41: 250-255.
20. Oppenheim C, Stanescu R, Dormont D, Crozier S, Marro B, Samson Y, Rancurel G, Marsault C: False-negative diffusion-weighted MR findings in acute ischemic stroke. AJNR Am J Neuroradiol 2000; 21: 1434-1440.
21. Rajajee V, Kidwell C, Starkman S, Ovbiagele B, Alger J, Villablanca P, Saver JL: Diagnosis of lacunar infarcts within 6 hours of onset by clinical and CT criteria versus MRI. J Neuroimaging 2008; 18: 66-72.
22. Siemonsen S, Mouridsen K, Holst B, Ries T, Finsterbusch J, Thomalla G, Ostergaard L, Fiehler J: Quantitative t2 values predict time from symptom onset in acute stroke patients.Stroke 2009; 40: 1612-1616.