Circulating MicroRNAs as biomarkers of colorectal cancer: Results from a genome-wide profiling and validation study

Clinical Gastroenterology and Hepatology

Volumn 11, Issue 6, 2013, Pages

  Giráldez, María Dolores ^a   Lozano, Juan José ^a   Ramírez, Georgina ^a   Hijona, Elizabeth ^b   Bujanda, Luis ^b   Castells, Antoni ^a   Gironella, Meritxell ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Advanced Adenoma; Colorectal Cancer Screening; Microarray; Small Noncoding RNA

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; MICRORNA 15B; MICRORNA 18A; MICRORNA 19A; MICRORNA 19B; MICRORNA 29A; MICRORNA 335; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER SCREENING; COLORECTAL CANCER; COLORECTAL TUMOR; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; RECEIVER OPERATING CHARACTERISTIC; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPAIN; TERTIARY HEALTH CARE; UPREGULATION; VALIDATION STUDY;

EID: 84878318144     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2012.12.009     Document Type: Article

References (24)

1. Esquela-Kerscher A., Slack F.J. Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 2006, 6:259-269.
2. Calin G.A., Croce C.M. MicroRNA signatures in human cancers. Nat Rev Cancer 2006, 6:857-866.
3. Mitchell P.S., Parkin R.K., Kroh E.M., et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 2008, 105:10513-10518.
4. Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2009. CA Cancer J Clin 2009, 59:225-249.
5. Gellad Z.F., Provenzale D. Colorectal cancer: national and international perspective on the burden of disease and public health impact. Gastroenterology 2010, 138:2177-2190.
6. Whitlock E.P., Lin J.S., Liles E., et al. Screening for colorectal cancer: a targeted, updated systematic review for the U.S. Preventive Services Task Force. Ann Intern Med 2008, 149:638-658.
7. Quintero E., Castells A., Bujanda L., et al. Colonoscopy versus fecal immunochemical testing in colorectal-cancer screening. N Engl J Med 2012, 366:697-706.
8. Ng E.K., Chong W.W., Jin H., et al. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 2009, 58:1375-1381.
9. Huang Z., Huang D., Ni S., et al. Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer. Int J Cancer 2010, 127:118-126.
10. Pu X.X., Huang G.L., Guo H.Q., et al. Circulating miR-221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expression. J Gastroenterol Hepatol 2010, 25:1674-1680.
11. Cheng H., Zhang L., Cogdell D.E., et al. Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis. PLoS One 2011, 6:e17745.
12. Chen J., Lozach J., Garcia E.W., et al. Highly sensitive and specific microRNA expression profiling using BeadArray technology. Nucleic Acids Res 2008, 36:e87.
13. Du P., Kibbe W.A., Lin S.M. Lumi: a pipeline for processing Illumina microarray. Bioinformatics 2008, 24:1547-1548.
14. Chang K.H., Mestdagh P., Vandesompele J., et al. MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer. BMC Cancer 2010, 10:173.
15. Smyth G.K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004, 3. Article3.
16. Culhane A.C., Thioulouse J., Perrière G., et al. MADE4: an R package for multivariate analysis of gene expression data. Bioinformatics 2005, 21:2789-2790.
17. Sabates-Bellver J., Van der Flier L.G., de Palo M., et al. Transcriptome profile of human colorectal adenomas. Mol Cancer Res 2007, 5:1263-1275.
18. Chen X., Ba Y., Ma L., et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 2008, 18:997-1006.
19. Diosdado B., van de Wiel M.A., Terhaar Sive Droste J.S., et al. MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. Br J Cancer 2009, 101:707-714.
20. Volinia S., Calin G.A., Liu C.G., et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006, 103:2257-2261.
21. Monzo M., Navarro A., Bandres E., et al. Overlapping expression of microRNAs in human embryonic colon and colorectal cancer. Cell Res 2008, 18:823-833.
22. Lanza G., Ferracin M., Gafà R., et al. mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer. Mol Cancer 2007, 6:54.
23. Motoyama K., Inoue H., Takatsuno Y., et al. Over- and under-expressed microRNAs in human colorectal cancer. Int J Oncol 2009, 34:1069-1075.
24. Earle J.S., Luthra R., Romans A., et al. Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma. J Mol Diagn 2010, 12:433-440.