Ulinastatin suppresses burn-induced lipid peroxidation and reduces fluid requirements in a swine model

Oxidative Medicine and Cellular Longevity

Volumn , Issue , 2013, Pages

  Luo, Hong Min ^a   Du, Ming Hua ^a   Lin, Zhi Long ^a   Hu, Quan ^b   Zhang, Lin ^b   Ma, Li ^a   Wang, Huan ^a   Wen, Yu ^a   Lv, Yi ^a   Lin, Hong Yuan ^b   Pi, Yu Li ^b   Hu, Sen ^a   Sheng, Zhi Yong ^a  

^a The General Hospital of the People's Liberation Army   (China)

^b Army General Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EXTRAVASCULAR LUNG WATERS; FLUID ACCUMULATION; INHIBITION OF LIPID PEROXIDATION; LIPID PEROXIDATION; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TISSUE CONCENTRATIONS; TISSUE WATER CONTENT; VASCULAR PERMEABILITY;

BIOLOGICAL ORGANS; OXIDATIVE STRESS; PLASMAS; RESUSCITATION; TISSUE;

LIPIDS;

CATALASE; RINGER LACTATE SOLUTION; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; ULINASTATIN; ANTIOXIDANT; GLYCOPROTEIN; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD LEVEL; BLOOD VESSEL PERMEABILITY; BODY SURFACE; BURN; CONTROLLED STUDY; DRUG INFUSION; EARLY INTERVENTION; ENZYME ACTIVITY; FEMALE; FLUID RESUSCITATION; FLUID RETENTION; HEART; HEART OUTPUT; HEMODYNAMICS; ILEUM; LIPID PEROXIDATION; LIVER; LUNG; LUNG BLOOD VESSEL; LUNG EXTRAVASCULAR FLUID; MEAN ARTERIAL PRESSURE; NONHUMAN; RANDOMIZATION; REPEATED DRUG DOSE; SKELETAL MUSCLE; SWINE; THERAPY DELAY; WATER CONTENT; ANIMAL; ANTIBODY SPECIFICITY; BLOOD; BLOOD PRESSURE; BODY FLUID; CAPILLARY PERMEABILITY; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; HEMATOCRIT; METABOLISM; PATHOPHYSIOLOGY;

SUIDAE;

ANIMALS; ANTIOXIDANTS; BLOOD PRESSURE; BODY FLUIDS; BURNS; CAPILLARY PERMEABILITY; DISEASE MODELS, ANIMAL; EXTRAVASCULAR LUNG WATER; FEMALE; GLYCOPROTEINS; HEMATOCRIT; HEMODYNAMICS; LIPID PEROXIDATION; ORGAN SPECIFICITY; SUS SCROFA; THIOBARBITURIC ACID REACTIVE SUBSTANCES; WATER;

EID: 84878293228     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2013/904370     Document Type: Article

References (44)

1. WISQARS, Overall Fire/Burn Nonfatal Injuries and Rates Per 100,000, 2010, United States, All Races, Both Sexes, All Ages, Disposition: All Cases Office of Statistics and Programming, National Center for Injury Prevention and Control, CDC
2. WISQARS, Fire/Burn Deaths and Rates Per 100,000, 2010, United States, All Races, Both Sexes, All Ages Office of Statistics and Programming, National Center for Injury Prevention and Control, CDC
3. Finkelstein E., Corso P. S., Miller T. R., The Incidence and Economic Burden of Injuries in the United States 2006 Oxford University Press
4. Herndon D. N., Total Burn Care 2007 3rd Saunders Elsevier
5. Ivy M. E., Possenti P. P., Kepros J., Atweh N. A., D'Aiuto M., Palmer J., Pineau M., Burns G. A., Caushaj P. F., Abdominal compartment syndrome in patients with burns. Journal of Burn Care and Rehabilitation 1999 20 5 351 353 2-s2.0-0032884193 (Pubitemid 29444959)
6. Oda J., Yamashita K., Inoue T., Harunari N., Ode Y., Mega K., Aoki Y., Noborio M., Ueyama M., Resuscitation fluid volume and abdominal compartment syndrome in patients with major burns. Burns 2006 32 2 151 154 2-s2.0-32044439375 10.1016/j.burns.2005.08.011 (Pubitemid 43197649)
7. Monafo W. W., Initial management of burns. New England Journal of Medicine 1996 335 21 1581 1586 2-s2.0-0029844891 10.1056/NEJM199611213352108 (Pubitemid 26384755)
8. Till G. O., Hatherill J. R., Tourtellotte W. W., Lipid peroxidation and acute lung injury after thermal trauma to skin. Evidence of a role for hydroxyl radical. American Journal of Pathology 1985 119 3 376 384 2-s2.0-0021833156 (Pubitemid 15051886)
9. Youn Y. K., Lalonde C., Demling R., Oxidants and the pathophysiology of burn and smoke inhalation injury. Free Radical Biology and Medicine 1992 12 5 409 415 2-s2.0-0026540505 10.1016/0891-5849(92)90090-4
10. Nguyen T. T., Cox C. S., Traber D. L., Gasser H., Redl H., Schlag G., Herndon D. N., Free radical activity and loss of plasma antioxidants, vitamin E, and sulfhydryl groups in patients with burns: the 1993 Moyer Award. Journal of Burn Care and Rehabilitation 1993 14 6 602 609 2-s2.0-0027438774 10.1097/00004630-199311000-00004 (Pubitemid 23360363)
11. Leff J. A., Burton L. K., Berger E. M., Anderson B. O., Wilke C. P., Repine J. E., Increased serum catalase activity in rats subjected to thermal skin injury. Inflammation 1993 17 2 199 204 2-s2.0-0027499128 (Pubitemid 23105192)
12. Cetinkale O., Belce A., Konukoglu D., Senyuva C., Gumustas M. K., Tas T., Evaluation of lipid peroxidation and total antioxidant status in plasma of rats following thermal injury. Burns 1997 23 2 114 116 2-s2.0-0030997845 10.1016/S0305-4179(96)00084-8 (Pubitemid 27230771)
13. Horton J. W., Free radicals and lipid peroxidation mediated injury in burn trauma: the role of antioxidant therapy. Toxicology 2003 189 1-2 75 88 2-s2.0-0038073062 10.1016/S0300-483X(03)00154-9 (Pubitemid 36725024)
14. Rauchova H., Vokurkova M., Koudelova J., Hypoxia-induced lipid peroxidation in the brain during postnatal ontogenesis. Physiological Research 2012 61 supplement 1 S89 S101
15. Demling R. H., Lalonde C., Systemic lipid peroxidation and inflammation induced by thermal injury persists into the post-resuscitation period. Journal of Trauma 1990 30 1 69 74 2-s2.0-0025060207 (Pubitemid 20052175)
16. Demling R. H., LaLonde C., Early postburn lipid peroxidation: effect of ibuprofen and allopurinol. Surgery 1990 107 1 85 93 2-s2.0-0025063894 (Pubitemid 20036812)
17. Daryani R., LaLonde C., Zhu D., Weidner M., Knox J., Demling R. H., Effect of endotoxin and a burn injury on lung and liver lipid peroxidation and catalase activity. Journal of Trauma 1990 30 11 1330 1334 2-s2.0-0025203566
18. Demling R., Ikegami K., Lalonde C., Increased lipid peroxidation and decreased antioxidant activity correspond with death after smoke exposure in the rat. Journal of Burn Care and Rehabilitation 1995 16 2 I 104 110 2-s2.0-0028937859 10.1097/00004630-199503000-00003
19. Lalonde C., Knox J., Youn Y. K., Demling R., Relationship between hepatic blood flow and tissue lipid peroxidation in the early postburn period. Critical Care Medicine 1992 20 6 789 796 2-s2.0-0026639453
20. Bekyarova G., Yankova T., Kozarev I., Yankov D., Reduced erythrocyte deformability related to activated lipid peroxidation during the early postburn period. Burns 1996 22 4 291 294 2-s2.0-0029930632 10.1016/0305-4179(95)00131-X (Pubitemid 26164134)
21. Tanaka H., Matsuda H., Shimazaki S., Hanumadass M., Matsuda T., Reduced resuscitation fluid volume for second-degree burns with delayed initiation of ascorbic acid therapy. Archives of Surgery 1997 132 2 158 161 2-s2.0-0031038647 (Pubitemid 27076534)
22. Sakurai M., Tanaka H., Matsuda T., Goya T., Shimazakidagger S., Matsuda H., Reduced resuscitation fluid volume for second-degree experimental burns with delayed initiation of vitamin C therapy (beginning 6 h after injury). Journal of Surgical Research 1997 73 1 24 27 2-s2.0-0031278004 10.1006/jsre.1997.5203 (Pubitemid 28068313)
23. Tanaka H., Lund T., Wiig H., Reed R. K., Yukioka T., Matsuda H., Shimazaki S., High dose vitamin C counteracts the negative interstitial fluid hydrostatic pressure and early edema generation in thermally injured rats. Burns 1999 25 7 569 574 2-s2.0-0033231812 10.1016/S0305-4179(99)00073-X (Pubitemid 29440899)
24. Dubick M. A., Williams C., Elgjo G. I., Kramer G. C., High-dose vitamin C infusion reduces fluid requirements in the resuscitation of burn-injured sheep. Shock 2005 24 2 139 144 2-s2.0-23344444441 10.1097/01.shk.0000170355.26060.e6 (Pubitemid 41105511)
25. Matsuda T., Tanaka H., Williams S., Hanumadass M., Abcarian H., Reyes H., Reduced fluid volume requirement for resuscitation of third-degree burns with high-dose vitamin C. Journal of Burn Care and Rehabilitation 1991 12 6 525 532 2-s2.0-0026323214
26. Matsuda T., Tanaka H., Shimazaki S., Matsuda H., Abcarian H., Reyes H., Hanumadass M., High-dose vitamin C therapy for extensive deep dermal burns. Burns 1992 18 2 127 131 2-s2.0-0026587376
27. Matsuda T., Tanaka H., Reyes H. M., Richter H. M., Hanumadass M. M., Shimazaki S., Matsuda H., Nyhus L. M., Baxter C. R., Antioxidant therapy using high dose vitamin C: reduction of postburn resuscitation fluid volume requirements. World Journal of Surgery 1995 19 2 287 291 2-s2.0-0029079326 10.1007/BF00308640
28. Koga Y., Fujita M., Tsuruta R., Koda Y., Nakahara T., Yagi T., Aoki T., Kobayashi C., Izumi T., Kasaoka S., Yuasa M., Maekawa T., Urinary trypsin inhibitor suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats. Neurological Research 2010 32 9 925 932 2-s2.0-77957583751 10.1179/016164110X12645013515133
29. Tanaka R., Fujita M., Tsuruta R., Fujimoto K., Aki H. S., Kumagai K., Aoki T., Kobayashi A., Izumi T., Kasaoka S., Yuasa M., Maekawa T., Urinary trypsin inhibitor suppresses excessive generation of superoxide anion radical, systemic inflammation, oxidative stress, and endothelial injury in endotoxemic rats. Inflammation Research 2010 59 8 597 606 2-s2.0-77955653376 10.1007/s00011-010-0166-8
30. Kudo Y., Egashira T., Yamanaka Y., Protective effect of ulinastatin against liver injury caused by ischemia-reperfusion in rats. Japanese Journal of Pharmacology 1992 60 3 239 245 2-s2.0-0027077676 (Pubitemid 23009057)
31. Luo H. M., Hu S., Zhou G. Y., Bai H. Y., Lv Y., Wang H. B., Lin H. Y., Sheng Z. Y., The effects of ulinastatin on systemic inflammation, visceral vasopermeability and tissue water content in rats with scald injury. Burns 2012 10.1016/j.burns.2012.11.004
32. Zhou L. W., Wang Y. L., Yan X. T., He X. H., Urinary trypsin inhibitor treatment ameliorates acute lung and liver injury resulting from sepsis in a rat model. Saudi Medical Journal 2008 29 3 368 373 2-s2.0-47549096076
33. Huang Y., Xie K., Zhang J., Dang Y., Qiong Z., Prospective clinical and experimental studies on the cardioprotective effect of ulinastatin following severe burns. Burns 2008 34 5 674 680 2-s2.0-44649141467 10.1016/j.burns.2007. 08.024
34. Yu J. R., Yan S., Liu X. S., Wu Y. J., Fu P. F., Wu L. H., Zheng S. S., Attenuation of graft ischemia-reperfusion injury by urinary trypsin inhibitor in mouse intestinal transplantation. World Journal of Gastroenterology 2005 11 11 1605 1609 2-s2.0-17144365447 (Pubitemid 40520799)
35. Htwe T., Suzuki M., Ouchi K., Fukuhara K., Matsuno S., Effects of urinastatin and free radical scavengers on hepatic lipid peroxidation in endotoxemia. Journal of Surgical Research 1996 61 1 206 214 2-s2.0-0030024234 10.1006/jsre.1996.0106 (Pubitemid 26066053)
36. Yamasaki F., Ishibashi M., Nakakuki M., Watanabe M., Shinkawa T., Mizota M., Protective action of ulinastatin against cisplatin nephrotoxicity in mice and its effect on the lysosomal fragility. Nephron 1996 74 1 158 167 2-s2.0-0029740027 (Pubitemid 26300664)
37. Cao Y. Z., Tu Y. Y., Chen X., Wang B. L., Zhong Y. X., Liu M. H., Protective effect of Ulinastatin against murine models of sepsis: inhibition of TNF- α and IL-6 and augmentation of IL-10 and IL-13. Experimental and Toxicologic Pathology 2012 64 2 543 547 2-s2.0-78649952176 10.1016/j.etp.2010. 11.011
38. Koizumi R., Kanai H., Maezawa A., Kanda T., Nojima Y., Naruse T., Therapeutic effects of Ulinastatin on experimental crescentic glomerulonephritis in rats. Nephron 2000 84 4 347 353 2-s2.0-0034068882 (Pubitemid 30179460)
39. Kuwa T., Jordan B. S., Cancio L. C., Use of power Doppler ultrasound to monitor renal perfusion during burn shock. Burns 2006 32 6 706 713 2-s2.0-33747884965 10.1016/j.burns.2006.01.017 (Pubitemid 44293061)
40. Tadros T., Traber D. L., Heggers J. P., Herndon D. N., Angiotensin II inhibitor DuP753 attenuates burn- and endotoxin-induced gut ischemia, lipid peroxidation, mucosal permeability, and bacterial translocation. Annals of Surgery 2000 231 4 566 576 2-s2.0-0034111039 10.1097/00000658-200004000-00017 (Pubitemid 30185865)
41. Gao C., Liu Y., Ma L., Wang S., Protective effects of ulinastatin on pulmonary damage in rats following scald injury. Burns 2012 38 7 1027 1034
42. Fang Y., Xu P., Gu C., Wang Y., Fu X. J., Yu W. R., Yao M., Ulinastatin improves pulmonary function in severe burn-induced acute lung injury by attenuating inflammatory response. The Journal of Trauma 2011 71 5 1297 1230
43. Lange N. R., Schuster D. P., The measurement of lung water. Critical Care 1999 3 2 R19 R24 2-s2.0-0032973757 10.1186/cc342 (Pubitemid 29272088)
44. Shimazaki E., Tanaka H., Ohta S., Yukioka T., Matsuda H., Shimazaki S., Effects of the antiprotease ulinastatin on mortality and oxidant injury in scalded rats. Archives of Surgery 1995 130 9 994 997 2-s2.0-0029151786