Adequate lymph node recovery improves survival in colorectal cancer patients

Journal of Surgical Oncology

Volumn 107, Issue 8, 2013, Pages 828-834

  Onitilo, Adedayo A ^a,b   Stankowski, Rachel V ^a   Engel, Jessica M ^a   Doi, Suhail A R ^b  

^a MARSHFIELD CLINIC   (United States)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

colorectal cancer; lymph node recovery; staging; survival

Indexed keywords

ARTICLE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; COLORECTAL CANCER; FEMALE; GROUPS BY AGE; HUMAN; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK REDUCTION; SURVIVAL RATE; TUMOR VOLUME;

ADULT; AGED; CHEMOTHERAPY, ADJUVANT; COLORECTAL NEOPLASMS; FEMALE; HUMANS; LOGISTIC MODELS; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM GRADING; NEOPLASM STAGING; ODDS RATIO; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 84878288307     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.23332     Document Type: Article

References (31)

1. American Cancer Society. Learn About Cancer: Colorectal Cancer Overview. Available at: http://www.cancer.org/Cancer/ColonandRectumCancer/OverviewGuide/ colorectal-cancer-overview-key-statistics. Accessed June 2, 2011.
2. Jemal A, Siegel R, Ward E, et al.: Cancer statistics, 2007. CA Cancer J Clin 2007; 57: 43-66. (Pubitemid 46148091)
3. Washington MK:, Colorectal carcinoma: Selected issues in pathologic examination and staging and determination of prognostic factors. Arch Pathol Lab Med 2008; 132: 1600-1607.
4. Lee HY, Choi HJ, Park KJ, et al.: Prognostic significance of metastatic lymph node ratio in node-positive colon carcinoma. Ann Surg Oncol 2007; 14: 1712-1717.
5. Quasar Collaborative Group, Gray R, Barnwell J, et al.: Adjuvant chemotherapy versus observation in patients with colorectal cancer: A randomised study. Lancet 2007; 370: 2020-2029.
6. Feezor RJ, Copeland EM, III, Hochwald SN:, Significance of micrometastases in colorectal cancer. Ann Surg Oncol 2002; 9: 944-953. (Pubitemid 35424627)
7. Chen SL, Bilchik AJ:, More extensive nodal dissection improves survival for stages I to III of colon cancer. Ann Surg 2006; 244: 602-610.
8. Choi HK, Law WL, Poon JT:, The optimal number of lymph nodes examined in stage II colorectal cancer and its impact on outcomes. BMC Cancer 2010; 10: 267-276.
9. Noura S, Ohue M, Kano S, et al.: Impact of metastatic lymph node ratio on node-positive colorectal cancer. World J Gastrointest Surg 2010; 2: 70-77.
10. Chen SL, Steele SR, Eberhardt J, et al.: Lymph node ratio as a quality and prognostic indicator in stage III colon cancer. Ann Surg 2011; 253: 82-87.
11. Ishizuka M, Nagata H, Takagi K, et al.: Insufficient lymph node dissection is an independent risk factor for postoperative cancer death in patients undergoing surgery for stage II colorectal cancer. Eur Surg Res 2011; 46: 57-64.
12. Kanemitsu Y, Komori K, Ishiguro S, et al.: The relationship of lymph node evaluation and colorectal cancer survival after curative resection: A multi-institutional study. Ann Surg Oncol 2012; 9: 2169-2177.
13. Kotake K, Honjo S, Sugihara K, et al.: Number of lymph nodes retrieved is an important determinant of survival of patients with stage II and III colorectal cancer. Jpn J Clin Oncol 2012; 4: 29-35.
14. Compton CC, Fielding LP, Burgart LJ, et al.: Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 2000; 124: 979-994. (Pubitemid 30602039)
15. National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology: Colon Cancer, Version 3.2011. Available at: http://www.nccn.org/professionals/physician-gls/pdf/colon.pdf Accessed June 2, 2011.
16. Schumacher P, Dineen S, Barnett C, Jr., et al.: The metastatic lymph node ratio predicts survival in colon cancer. Am J Surg 2007; 194: 827-832. (Pubitemid 350086537)
17. Derwinger K, Carlsson G, Gustavsson B:, A study of lymph node ratio as a prognostic marker in colon cancer. Eur J Surg Oncol 2008; 34: 771-775.
18. Peng J, Xu Y, Guan Z, et al.: Prognostic significance of the metastatic lymph node ratio in node-positive rectal cancer. Ann Surg Oncol 2008; 15: 3118-3123.
19. Kim YS, Kim JH, Yoon SM, et al.: Lymph node ratio as a prognostic factor in patients with stage III rectal cancer treated with total mesorectal excision followed by chemoradiotherapy. Int J Radiat Oncol Biol Phys 2009; 74: 796-802.
20. Moug SJ, Saldanha JD, McGregor JR, et al.: Positive lymph node retrieval ratio optimizes patient staging in colorectal cancer. Br J Cancer 2009; 100: 1530-1533.
21. Vaccaro CA, Im V, Rossi GL, et al.: Lymph node ratio as prognosis factor for colon cancer treated by colorectal surgeons. Dis Colon Rectum 2009; 52: 1244-1250.
22. Storli K, Lindboe CF, Kristofferson C, et al.: Lymph node harvest in colon cancer specimens depends on tumour factors, patients and doctors, but foremost on specimen handling. APMIS 2010; 119: 127-134.
23. Lagoudianakis E, Pappas A, Koronakis N, et al.: Lymph node harvesting in colorectal carcinoma specimens. Tumori 2011; 97: 74-78.
24. Minhas JS, Igali L:, Lymph node correlations and theresholds in colorectal cancer specimens. Int J Surg Pathol 2011; 19: 462-468.
25. Porter GA, Urquhart R, Bu J, et al.: Improving nodal harvest in colorectal cancer: So what ? Ann Surg Oncol 2012; 19: 1066-1073.
26. Bamboat ZM, Deperalta D, Dursun A, et al.: Factors affecting lymph node yield from patients undergoing colectomy for cancer. Int J Colorectal Dis 2011; 26: 1163-1168.
27. Chang GJ, Rodriguez-Bigas MA, Skibber JM, et al.: Lymph node evaluation and survival after curative resection of colon cancer: Systematic review. J Natl Cancer Inst 2007; 99: 433-441. (Pubitemid 47073566)
28. Fan L, Levy M, Aguilar CE, et al.: Lymph node retrieval from colorectal resection specimens for adenocarcinoma: Is it worth the extra effort to find at least 12 nodes ? Colorectal Dis 2011; 13: 1377-1383.
29. Zhou Z, Wu X, Wang R, et al.: Optimal use of adjuvant chemotherapy in stage II colorectal cancer. Int J Colorectal Dis 2011; 26: 867-873.
30. Scott KWM, Grace RH:, Detection of lymph node metastases in colorectal carcinoma before and after fat clearance. Br J Surg 1989; 78: 1165-1167. (Pubitemid 19284443)
31. Baxter NN, Virnig DJ, Rothenberger DA, et al.: Lymph node evaluation in colorectal cancer patients: A population-based study. J Natl Cancer Inst 2005; 97: 219-225. (Pubitemid 40277372)