A study of lymph node ratio as a prognostic marker in colon cancer

European Journal of Surgical Oncology

Volumn 34, Issue 7, 2008, Pages 771-775

  Derwinger, K ^a   Carlsson, G ^a   Gustavsson, B ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Colon cancer; Lymph node ratio; Prognosis; Survival

Indexed keywords

ANTINEOPLASTIC AGENT;

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER DIAGNOSIS; CANCER REGISTRY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL FEATURE; COLON CANCER; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; HIGH RISK POPULATION; HUMAN; LYMPH NODE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; STATISTICAL SIGNIFICANCE; UNSPECIFIED SIDE EFFECT;

ADULT; AGED; AGED, 80 AND OVER; COLONIC NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES;

EID: 51749125736     PISSN: 07487983     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejso.2007.11.002     Document Type: Article

References (25)

1. Oncological centre in Western Region of Sweden. Regional guidelines and statistics; 2005.
2. Glimelius B., Dahl O., Cedermark B., et al. Adjuvant chemotherapy in colorectal cancer: a joint analysis of randomised trials by the nordic gastrointestinal tumour adjuvant therapy group. Acta Oncol 44 8 (2005) 904-912
3. Kehoe J., and Khatri V.P. Staging and prognosis of colon cancer. Surg Oncol Clin N Am 15 1 (2006) 129-146
4. Lemmens V.E., Verheij C.D., Janssen-Heijnen M.L., et al. Mixed adherence to clinical practice guidelines for colorectal cancer in the southern Netherlands in 2002. Eur J Surg Oncol 32 2 (2006) 168-173
5. Ratto C., Sofo L., Ippoliti M., et al. Accurate lymph-node detection in colorectal specimens resected for cancer is of prognostic significance. Dis Colon Rectum 42 2 (1999) 143-154 discussion 154-8
6. Engwegen J.Y., Gast M.C., Schellens J.H., et al. Clinical proteomics: searching for better tumour markers with SELDI-TOF mass spectrometry. Trends Pharmacol Sci 27 5 (2006) 251-259
7. Ohlsson L., Hammarstrom M.L., Israelsson A., et al. Biomarker selection for detection of occult tumour cells in lymph nodes of colorectal cancer patients using real-time quantitative RT-PCR. Br J Cancer 95 2 (2006) 218-225
8. Kobayashi H., Ueno H., Hashiguchi Y., et al. Distribution of lymph node metastasis is a prognostic index in patients with stage III colon cancer. Surgery 139 4 (2006) 516-522
9. Dhar D.K., Yoshimura H., Kinukawa N., et al. Metastatic lymph node size and colorectal cancer prognosis. J Am Coll Surg 200 1 (2005) 20-28
10. Inoue K., Nakane Y., Iiyama H., et al. The superiority of ratio-based lymph node staging in gastric carcinoma. Ann Surg Oncol 9 1 (2002) 27-34
11. Voordeckers M., Vinh-Hung V., Van de Steene J., et al. The lymph node ratio as prognostic factor in node-positive breast cancer. Radiother Oncol 70 3 (2004) 225-230
12. Berger A.C., Sigurdson E.R., LeVoyer T., et al. Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol 23 34 (2005) 8706-8712
13. UICC/AJCC. Manual of TNM classification of malignant tumors. 5th ed.; 1997.
14. Sargent D.J., Wieand H.S., Haller D.G., et al. Disease-free survival versus overall survival as a primary end point for adjuvant colon cancer studies: individual patient data from 20,898 patients on 18 randomized trials. J Clin Oncol 23 34 (2005) 8664-8670
15. Wolters U., Stutzer H., Keller H.W., et al. Colorectal cancer - a multivariate analysis of prognostic factors. Eur J Surg Oncol 22 6 (1996) 592-597
16. Compton C.C. Key issues in reporting common cancer specimens: problems in pathologic staging of colon cancer. Arch Pathol Lab Med 130 3 (2006) 318-324
17. Lemmens V.E., van Lijnschoten I., Janssen-Heijnen M.L., et al. Pathology practice patterns affect lymph node evaluation and outcome of colon cancer: a population-based study. Ann Oncol 17 12 (2006) 1803-1809
18. Jestin P., Pahlman L., Glimelius B., et al. Cancer staging and survival in colon cancer is dependent on the quality of the pathologists' specimen examination. Eur J Cancer 41 14 (2005) 2071-2078
19. National Board of Health in Sweden. National guidelines for colorectal cancer; 2006.
20. Derwinger K., Carlsson G., and Gustavsson B. Stage migration in colorectal cancer related to improved lymph node assessment. Eur J Surg Oncol 33 7 (2007 Sep) 849-853
21. Jestin P., Nilsson J., Heurgren M., et al. Emergency surgery for colonic cancer in a defined population. Br J Surg 92 1 (2005) 94-100
22. Lee H.Y., Choi H.J., Park K.J., et al. Prognostic significance of metastatic lymph node ratio in node-positive colon carcinoma. Ann Surg Oncol 14 5 (2007 May) 1712-1717
23. Iqbal S., Stoehlmacher J., and Lenz H.J. Tailored chemotherapy for colorectal cancer: a new approach to therapy. Cancer Invest 22 5 (2004) 762-773
24. Westra J.L., Plukker J.T., Buys C.H., et al. Genetic alterations in locally advanced stage II/III colon cancer: a search for prognostic markers. Clin Colorectal Cancer 4 4 (2004) 252-259
25. Mader R.M. Links between biology, prognosis and prediction of response to chemotherapy in colorectal cancer. Onkologie 29 7 (2006) 334-341