Anaphylaxis to neuromuscular blocking drugs: Incidence and cross-reactivity in Western Australia from 2002 to 2011

British Journal of Anaesthesia

Volumn 110, Issue 6, 2013, Pages 981-987

  Sadleir, P H M ^a   Clarke, R C ^a   Bunning, D L ^a   Platt, P R ^a  

^a SIR CHARLES GAIRDNER HOSPITAL   (Australia)

Author keywords

anaphylaxis; cross reactivity; neuromuscular blocking drugs; rocuronium

Indexed keywords

ATRACURIUM BESILATE; CISATRACURIUM; IMMUNOGLOBULIN E; NEUROMUSCULAR BLOCKING AGENT; PANCURONIUM; ROCURONIUM; SUXAMETHONIUM; VECURONIUM;

ADOLESCENT; ADULT; AGED; ANAPHYLAXIS; ARTICLE; AUSTRALIA; CHILD; CONTROLLED STUDY; CROSS REACTION; DISEASE SEVERITY; DRUG EXPOSURE; DRUG HYPERSENSITIVITY; FEMALE; HUMAN; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD;

EID: 84878284972     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aes506     Document Type: Article

References (21)

1. Mertes PM, Aimone-Gastin I, Gueant-Rodriguez RM, et al. Hypersensitivity reactions to neuromuscular blocking agents. Curr Pharm Des 2008; 14: 2809-25
2. Levy JH. Anaphylactic reactions to neuromuscular blocking drugs: are we making the correct diagnosis? Anesth Analg 2004; 98: 881-2. (Pubitemid 38405388)
3. Mertes PM, Guttormsen AB, Harboe T, et al. Can spontaneous adverse event reporting systems really be used to compare rates of adverse events between drugs? Anesth Analg 2007; 104: 471-2. (Pubitemid 46146792)
4. Mertes PM, Laxenaire MC, Alla F, Groupe d'Etudes des Reactions Anaphylactoides Peranesthesiques. Anaphylactic and anaphylactoid reactions occurring during anesthesia in France in 1999- 2000. Anesthesiology 2003; 99: 536-45 (Pubitemid 37051967)
5. Laxenaire MC, Mertes PM, Groupe d'Etudes des Reactions Anaphylactoides Peranesthesiques. Anaphylaxis during anesthesia. Results of a two-year survey in France. Br J Anaesth 2001; 87: 549-58 (Pubitemid 32936731)
6. Rose M, Fisher M. Rocuronium: high risk for anaphylaxis? Br J Anaesth 2001; 86: 678-82.
7. Fisher MM, Bowey CJ. Intradermal compared with prick testing in the diagnosis of anaesthetic allergy. Br J Anaesth 1997; 79: 59-63 (Pubitemid 27326761)
8. Florvaag E, Johansson SG, Oman H, et al. Prevalence of IgE antibodies to morphine. Relation to the high and low incidences of NMBA anaphylaxis in Norway and Sweden, respectively. Acta Anaesthesiol Scand 2005; 49: 437-44 (Pubitemid 40488565)
9. Guttormsen AB. Allergic reactions during anaesthesia-increased attention to the problem in Denmark and Norway. Acta Anaesthesiol Scand 2001; 45: 1189-90
10. Florvaag E, Johansson SG, Irgens A, de Pater GH. IgE-sensitisation to the cough suppressant pholcodine and the effects of its withdrawal from the Norgwegian market. Allergy 2011; 66: 955-60
11. Mertes PM, Alla F, Trechot P, Auroy Y, Jougla E, Groupe d'Etudes des Reactions Anaphylactoides Peranesthesiques. Anaphylaxis during anesthesia in France: an 8-year national survery. J Allergy Clin Immunol 2011; 128: 366-73
12. Bhananker SM, O'Donnell JT, Salemi JR, Bishop MJ. The risk of anaphylactic reactions to rocuronium in the United States is comparable to that of vecuronium: an analysis of Food and Drug Administration reporting of adverse events. Anesth Analg 2005; 101: 819-22 (Pubitemid 41208517)
13. Johansson SG, Florvaag E, Oman H, et al. National pholcodine consumption and prevalence of IgE-sensitisation: a multicentre study. Allergy 2010; 65: 498-502
14. Watkins J. Incidence of UK reactions involving rocuronium may simply reflect market use. Br J Anaesth 2001; 87: 522 (Pubitemid 32827501)
15. Laake JH, Rottingen JA. Rocuronium and anaphylaxis-a statistical challenge. Acta Anaesthesiol Scand 2001; 45: 1196-203
16. Harboe T, Guttormsen AB, Irgens A, Dybendal T, Florvaag E. Anaphylaxis during anesthesia in Norway: a 6-year single-center follow-up study. Anesthesiology 2005; 102: 897-903 (Pubitemid 40586528)
17. Brereton A. Muscle relaxants-an increasing problem? A 10 year audit. Royal Adelaide Hospital, Adelaide, Australia, 2011. Abstract presented at 2011 ANZCA annual scientific meeting. Available from http://tinyurl.com/8jrmtw8 (accessed 8 August 2012)
18. Tsong Y. Comparing reporting rates of adverse events between drugs with adjustment for year of marketing and secular trends in total reporting. J Biopharm Stat 1995; 5: 95-114
19. Gurrieri C, Weingarten TN, Martin DP, et al. Allergic reactions during anesthesia at a large United States referral center. Anesth Analg 2011; 113: 1202-12
20. Report of the International Narcotics Control Board for 2009 (E/INCB/2009/1). Narcotic Drugs Estimated World Requirements for 2010. Statistics for 2008. New York: United Nations, 2010; 209. Available from http://tinyurl.com/yk9ydav (accessed 8 August 2012).
21. Baldo BA, Fisher MM, Pham NH. On the origin and specificity of antibodies to neuromuscular blocking (muscle relaxant) drugs: an immunochemical perspective. Clin Exp Allerg 2009; 39: 325-44