A retrospective two-center study of antiepileptic prophylaxis in patients with surgically treated high-grade gliomas

Neurology India

Volumn 61, Issue 2, 2013, Pages 131-137

  Garbossa, Diego ^a   Panciani, Pier Paolo ^b   Angeleri, Romina ^a   Battaglia, Luigi ^a   Tartara, Fulvio ^a   Ajello, Marco ^a   Agnoletti, Alessandro ^a   Versari, Pietro ^c   Ducati, Alessandro ^a   Fontanella, Marco ^b   Spena, Giannantonio ^b  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c Civil Hospital   (Italy)

Author keywords

Antiepileptic Drugs; Glioma; Levetiracetam; Prophylaxis; Seizures; Surgery

Indexed keywords

CARBAMAZEPINE; ETIRACETAM; OXCARBAZEPINE; VALPROIC ACID;

ADULT; AGE DISTRIBUTION; AGED; ANTICONVULSANT THERAPY; ARTICLE; CANCER GRADING; CLINICAL EVALUATION; COHORT ANALYSIS; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; EXPLANATORY VARIABLE; FEMALE; FOCAL EPILEPSY; FOLLOW UP; GLIOBLASTOMA; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OUTCOME ASSESSMENT; POSTOPERATIVE PERIOD; PREDICTOR VARIABLE; PREOPERATIVE TREATMENT; RETROSPECTIVE STUDY; VERTIGO;

ADULT; AGED; ANTICONVULSANTS; BRAIN NEOPLASMS; CRANIOTOMY; FEMALE; GLIOMA; HUMANS; MALE; MIDDLE AGED; PIRACETAM; POSTOPERATIVE PERIOD; RETROSPECTIVE STUDIES; SEIZURES; TREATMENT OUTCOME;

EID: 84878269447     PISSN: 00283886     EISSN: 19984022     Source Type: Journal    
DOI: 10.4103/0028-3886.111118     Document Type: Article

References (30)

1. Herman ST. Epilepsy after brain insult: Targeting epileptogenesis. Neurology 2002;59: 21-6.
2. Glantz MJ, Cole BF, Forsyth PA, Recht LD, Wen PY, Chamberlain MC, et al. Practice parameter: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors. Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2000; 54: 1886-93. (Pubitemid 30327107)
3. Franceschetti S, Binelli S, Casazza M, Lodrini S, Panzica F, Pluchino F, et al. Influence of surgery and antiepileptic drugs on seizures symptomatic of cerebral tumours. Acta Neurochir 1990;103: 47-51. (Pubitemid 20155189)
4. Lee ST, Lui TN, Chang CN, Cheng WC, Wang DJ, Heimburger RF, et al. Prophylactic anticonvulsants for prevention of immediate and early postcraniotomy seizures. Surg Neurol 1989;31: 361-4. (Pubitemid 19127512)
5. North JB, Penhall RK, Hanieh A, Frewin DB, Taylor WB. Phenytoin and postoperative epilepsy. A double-blind study. J Neurosurg 1983;58: 672-7. (Pubitemid 13131507)
6. Hildebrand J, Lecaille C, Perennes J, Delattre JY. Epileptic seizures during follow-up of patients treated for primary brain tumors. Neurology 2005;65: 212-5. (Pubitemid 41022363)
7. Lwu S, Hamilton MG, Forsyth PA, Cairncross JG, Parney IF. Use of peri-operative anti-epileptic drugs in patients with newly diagnosed high-grade malignant glioma: A single center experience. J Neurooncol 2010;96: 403-8.
8. Tremont-Lukats IW, Ratilal BO, Armstrong T, Gilbert MR. Antiepileptic drugs for preventing seizures in people with brain tumors. Cochrane Database Syst Rev 2008;16:CD004424.
9. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007;114: 97-109. (Pubitemid 47103521)
10. Foy PM, Copeland GP, Shaw MDM. The natural history of postoperative seizures. Acta Neurochir 2004;57: 15-22.
11. Kerrigan S, Grant R. Antiepileptic drugs for treating seizures in adults with brain tumours. Cochrane Database Syst Rev 2011;(8):CD008586.
12. Siomin V, Angelov L, Li L, Vogelbaum MA. Results of a survey of neurosurgical practice patterns regarding the prophylactic use of anti-epilepsy drugs in patients with brain tumors. J Neurooncol 2005;74: 211-5. (Pubitemid 41478921)
13. Cockey GH, Amann ST, Reents SB, Lynch JW Jr. Stevens-Johnson syndrome resulting from whole-brain radiation and phenytoin. Am J Clin Oncol 1996;19: 32-4. (Pubitemid 26037669)
14. Delattre JY, Safai B, Posner JB. Erythema multiforme and Stevens-Johnson syndrome in patients receiving cranial irradiation and phenytoin. Neurology 1988;38: 194-8. (Pubitemid 18036835)
15. Mamon HJ, Wen PY, Burns AC, Loeffler JS. Allergic skin reactions to anticonvulsant medications in patients receiving cranial radiation therapy. Epilepsia 1999;40: 341-4. (Pubitemid 29164800)
16. Vecht CJ, Wagner GL, Wilms EB. Interactions between antiepileptic and chemotherapeutic drugs. Lancet Neurol 2003;2: 404-9. (Pubitemid 36793932)
17. Oberndorfer S, Piribauer M, Marosi C, Lahrmann H, Hitzenberger P, Grisold W. P450 enzyme inducing and non-enzyme inducing antiepileptics in glioblastoma patients treated with standard chemotherapy. J Neurooncol 2005;72: 255-60. (Pubitemid 40867409)
18. Kern K, Schebesch KM, Schlaier J, Hansen E, Feigl GC, Brawanski AT, et al. Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy. J Clin Neurosci 2012;19: 99-100.
19. Bobustuc GC, Baker CH, Limaye A, Jenkins WD, Pearl G, Avgeropoulos NG, et al. Levetiracetam enhances p53-mediated MGMT inhibition and sensitizes glioblastoma cells to temozolomide. Neuro Oncol 2010;12: 917-27.
20. Weller M, Gorlia T, Cairncross JG, van den Bent MJ, Mason W, Belanger K, et al. Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma. Neurology 2011;77: 1156-64.
21. Wagner GL, Wilms EB, Van Donselaar CA, Vecht C. Levetiracetam: Preliminary experience in patients with primary brain tumours. Seizure 1996;12: 585-6.
22. Newton HB, Goldlust SA, Pearl D. Retrospective analysis of the efficacy and tolerability of levetiracetam in brain tumor patients. J Neurooncol 2006;78: 99-102. (Pubitemid 43786667)
23. Siddiqui F, Wen P, Dworetzky B, Cabello D, Bromfield E. Use of levetiracetam in patients with brain tumours. Epilepsia 2002;43: 297.
24. Bähr O, Hermisson M, Rona S, Rieger J, Nussbaum S, Körtvelyessy P, et al. Intravenous and oral levetiracetam in patients with a suspected primary brain tumor and symptomatic seizures undergoing neurosurgery: the HELLO trial. Acta Neurochir 2012;154: 229-35.
25. Zachenhofer I, Donat M, Oberndorfer S, Roessler K. Perioperative levetiracetam for prevention of seizures in supratentorial brain tumor surgery. J Neurooncol 2011;101: 101-6.
26. de Groot M, Aronica E, Heimans JJ, Reijneveld JC. Synaptic vesicle protein 2A predicts response to levetiracetam in patients with glioma. Neurology 2011;77: 532-9.
27. Kuijlen JM, Teernstra OP, Kessels AG, Herpers MJ, Beuls EA. Effectiveness of antiepileptic prophylaxis used with supratentorial craniotomies: A meta-analysis. Seizure 1996;5: 291-8. (Pubitemid 26405384)
28. Temkin NR. Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: Meta-analysis of controlled trials. Epilepsia 2001;42: 515-24. (Pubitemid 32322197)
29. De Santis A, Villani R, Sinisi M, Stocchetti N, Perucca E. Add-on phenytoin fails to prevent early seizures after surgery for supratentorial brain tumors: A randomized controlled study. Epilepsia 2002;43: 175-82. (Pubitemid 34225999)
30. Sirven JI, Wingerchuk DM, Drazkowski JF, Lyons MK, Zimmerman RS. Seizure prophylaxis in patients with brain tumors: A meta-analysis. Mayo Clin Proc 2004;79: 1489-94. (Pubitemid 39578871)