Canadian traditionally used medicinal plants: Can they play a role in antituberculosis drug development?

Future Medicinal Chemistry

Volumn 5, Issue 8, 2013, Pages 853-855

  Gray, Christopher A ^a   Johnson, John A ^a   Webster, Duncan ^b  

^a UNIVERSITY OF NEW BRUNSWICK   (Canada)

^b SAINT JOHN REGIONAL HOSPITAL   (Canada)

Author keywords

antimycobacterial agents; ethnopharmacology; fungal endophytes; medicinal plants; Mycobacterium tuberculosis; natural products; tuberculosis

Indexed keywords

ANTIMYCOBACTERIAL AGENT; BEDAQUILINE; DELAMANID; HERBACEOUS AGENT; TUBERCULOSTATIC AGENT;

CLINICAL TRIAL (TOPIC); DISEASE TRANSMISSION; DRUG INDUSTRY; ENDOPHYTE; ETHNOPHARMACOLOGY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MEDICINAL PLANT; MORTALITY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; TISSUE SPECIFICITY; TRADITIONAL MEDICINE; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; BIOLOGICAL AGENTS; CANADA; HUMANS; MEDICINE, TRADITIONAL; MYCOBACTERIUM TUBERCULOSIS; PLANTS, MEDICINAL; TUBERCULOSIS;

EID: 84878266170     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc.13.64     Document Type: Review

References (20)

1. WHO. Global Tuberculosis Report. WHO press, Geneva, Switzerland 1-272 (2012).
2. Voelker R. MDR-TB has new drug foe after fast-track approval. JAMA 309(5), 430-430 (2013).
3. Gler MT, Skripconoka V, Sanchez-Garavito E et al. Delamanid for multidrug-resistant pulmonary tuberculosis. N. Engl. J. Med. 366(23), 2151-2160 (2012).
4. Danishefsky S. On the potential of natural products in the discovery of pharma leads: a case for reassessment. Nat. Prod. Rep. 27(8), 1114-1116 (2010).
5. Cordell GA, Colvard MD. Natural products and traditional medicine: turning on a paradigm. J. Nat. Prod. 75(3), 514-525 (2012).
6. Moerman DE. Native American Ethnobotany. Timber Press, OR, USA, 1-927 (1998).
7. Jones NP, Arnason JT, Abou-Zaid M, Akpagana K, Sanchez-Vindas P, Smith ML. Antifungal activity of extracts from medicinal plants used by First Nations peoples of eastern Canada. J. Ethnopharmacol. 73(1-2), 191-198 (2000).
8. McCutcheon AR, Roberts TE, Gibbons E et al. Antiviral screening of British Columbian medicinal plants. J. Ethnopharmacol. 49(2), 101-110 (1995).
9. McCutcheon AR, Ellis SM, Hancock REW, Towers GHN. Antibiotic screening of medicinal plants of the British Columbian native peoples. J. Ethnopharmacol. 37(3), 213-223 (1992).
10. McCutcheon AR, Ellis SM, Hancock REW, Towers GHN. Antifungal screening of medicinal plants of British Columbian native peoples. J. Ethnopharmacol. 44(3), 157-169 (1994).
11. McCutcheon AR, Stokes RW, Thorson LM, Ellis SM, Hancock REW, Towers GHN. Anti-mycobacterial screening of British Columbian medicinal plants. Int. J. Pharmacogn. 35(2), 77-83 (1997).
12. Donoghue HD, Spigelman M, Greenblatt CL et al. Tuberculosis: from prehistory to Robert Koch, as revealed by ancient DNA. Lancet Infect. Dis. 4(9), 584-592 (2004).
13. Gomez I Prat J, De Souza SM. Prehistoric tuberculosis in America: adding comments to a literature review. Mem. Inst. Oswaldo Cruz 98(Suppl. 1), 151-159 (2003).
14. Royal Commission on Aboriginal Peoples. The Path To Healing: Report Of The National Round Table On Aboriginal Health And Social Issues. Government of Canada, Ottawa, Canada (1993).
15. Aly AH, Debbab A, Kjer J, Proksch P. Fungal endophytes from higher plants: a prolific source of phytochemicals and other bioactive natural products. Fungal Divers. 41(1), 1-16 (2010).
16. Kaul S, Gupta S, Ahmed M, Dhar M. Endophytic fungi from medicinal plants: a treasure hunt for bioactive metabolites. Phytochem. Rev. 1-19 (2012).
17. Zhang HW, Song YC, Tan RX. Biology and chemistry of endophytes. Nat. Prod. Rep. 23(5), 753-771 (2006).
18. Canadian Forest Service. The State of Canada's Forests. Annual Report 51. Natural Resources Canada, Ottawa, Canada (2012).
19. Stop TB Partnership. Working group on new TB drugs: drug pipeline. www.newtbdrugs.org/pipeline.php (Accessed 1 March 2013
20. Université de Montréal. CIHR Team in Aboriginal Antidiabetic Medicines. www.taam-emaad.umontreal.ca (Accessed 5 March 2013