Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease

Journal of Bone and Mineral Research

Volumn 28, Issue 6, 2013, Pages 1489-1500

  Teramachi, Jumpei ^a   Hiruma, Yuko ^b   Ishizuka, Seiichi ^b   Ishizuka, Hisako ^b   Brown, Jacques P ^c   Michou, Laëtitia ^c   Cao, Huiling ^b   Galson, Deborah L ^b   Subler, Mark A ^d   Zhou, Hua ^e   Dempster, David W ^e   Windle, Jolene J ^d   Roodman, G David ^a   Kurihara, Noriyoshi ^a  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c LAVAL UNIVERSITY   (Canada)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^e New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

ATF7; OSTEOCLASTS; PAGET'S DISEASE; TAF12; VITAMIN D

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 7; CYCLIC AMP; CYTOCHROME P450; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEIC ACID BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR IID; UNCLASSIFIED DRUG; VITAMIN D; VITAMIN D RECEPTOR;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL ACTIVITY; CELL LINEAGE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HYPERSENSITIVITY; MORPHOMETRICS; MOUSE; MULTINUCLEAR CELL; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PAGET BONE DISEASE; PHENOTYPE; PRECURSOR; PROMOTER REGION; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; VITAMIN D RESPONSIVE ELEMENT; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTORS; ANIMALS; CALCITRIOL; FEMALE; HUMANS; MALE; MICE; MICE, TRANSGENIC; OSTEITIS DEFORMANS; OSTEOCLASTS; RANK LIGAND; RESPONSE ELEMENTS; STEM CELLS; STEROID HYDROXYLASES; TATA-BINDING PROTEIN ASSOCIATED FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84878263632     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1884     Document Type: Article

References (29)

1. Kanis JA., Pathophysiology and treatment of Paget's disease of bone 2nd ed. London: Martin Dunitz; 1998.
2. Maldague B, Malghem J., Dynamic radiologic patterns of Paget's disease of bone. Clin Orthop Relat Res. 1987; 217: 126-51.
3. Kukita A, Chenu C, McManus LM, Mundy GR, Roodman GD., Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease. J Clin Invest. 1990; 85: 1280-6.
4. Mengus G, May M, Jacq X, Staub A, Tora L, Chambon P, Davidson I., Cloning and characterization of hTAFII18, hTAFII20 and hTAFI I28: three subunits of the human transcription factor TFIID. EMBO J. 1995; 14: 1520-31.
5. Mengus G, Gangloff YG, Carré L, Lavigne AC, Davidson I., The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D (3) and thyroid hormone receptors. J Biol Chem. 2000; 275: 10064-71.
6. Hoffmann A, Roeder RG., Cloning and characterization of human TAF20/15. Multiple interactions suggest a central role in TFIID complex formation. J Biol Chem. 1996; 271: 18194-202.
7. II-17, a VDR binding protein, in the increased osteoclast formation in Paget's disease. J Bone Miner Res. 2004; 19: 1154-64.
8. Kurihara N, Hiruma Y, Yamana K, Michou L, Rousseau C, Morissette J, Galson DL, Teramachi J, Zhou H, Dempster DW, Windle JJ, Brown JP, Roodman GD., Contributions of the measles virus nucleocapsid gene and the SQSTM1/p62(P392L) mutation to Paget's disease. Cell Metab. 2011; 13: 23-34.
9. Kurihara N, Hiruma Y, Zhou H, Subler MA, Dempster DW, Singer FR, Reddy SV, Gruber HE, Windle JJ, Roodman GD., Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease. J Clin Invest. 2007; 117: 133-42.
10. Kurihara N, Zhou H, Reddy SV, Garcia Palacios V, Subler MA, Dempster DW, Windle JJ, Roodman GD., Expression of measles virus nucleocapsid protein in osteoclasts induces Paget's disease-like bone lesions in mice. J Bone Miner Res. 2006; 21: 446-55.
11. Hiruma Y, Kurihara N, Subler MA, Zhou H, Boykin CS, Zhang H, Ishizuka S, Dempster DW, Roodman GD, Windle JJ., A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironment. Hum Mol Genet. 2008; 17: 3708-19.
12. Hamard PJ, Dalbies-Tran R, Hauss C, Davidson I, Kedinger C, Chatton B., A functional interaction between ATF7 and TAF12 that is modulated by TAF4. Oncogene. 2005; 24: 3472-83.
13. Voulgari A, Voskou S, Tora L, Davidson I, Sasazuki T, Shirasawa S, Pintzas A., TATA box-binding protein-associated factor 12 is important for RAS-induced transformation properties of colorectal cancer cells. Mol Cancer Res. 2008; 6: 1071-83.
14. Kurihara N, Reddy SV, Menaa C, Anderson D, Roodman GD., Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype. J Clin Invest. 2000; 105: 607-14.
15. Reddy SV, Scarcez T, Windle JJ, Leach RJ, Hundley JE, Chirgwin JM, Chou JY, Roodman GD., Cloning and characterization of the 5′-flanking region of the mouse tartrate-resistant acid phosphatase gene. J Bone Miner Res. 1993; 8: 1263-70.
16. Reddy SV, Hundley JE, Windle JJ, Alcantara O, Linn R, Leach RJ, Boldt DH, Roodman GD., Characterization of the mouse tartrate-resistant acid phosphatase (TRAP) gene promoter. J Bone Miner Res. 1995; 4: 601-6.
17. Nagy A, Gertsenstein M, Vintersten K, Behringer R., Manipulating the Mouse Embryo. A Laboratory Manual 3rd ed. Cold Spring Harbor. NY: CSHL Press; 2003.
18. Yu S, Franceschi RT, Luo M, Fan J, Jiang D, Cao H, Kwon TG, Lai Y, Zhang J, Patrene K, Hankenson K, Roodman GD, Xiao G., Critical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in bone. PLoS One. 2009; 4: e7583.
19. Yu S, Jiang Y, Galson DL, Luo M, Lai Y, Lu Y, Ouyang HJ, Zhang J, Xiao G., General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2. J Biol Chem. 2008; 283: 5542-3.
20. Krötz F, de Wit C, Sohn HY, Zahler S, Gloe T, Pohl U, Plank C., Magnetofection-a highly efficient tool for antisense oligonucleotide delivery in vitro and in vivo. Mol Ther. 2003; 7: 700-10.
21. Hofmann A, Wenzel D, Becher UM, Freitag DF, Klein AM, Eberbeck D, Schulte M, Zimmermann K, Bergemann C, Gleich B, Roell W, Weyh T, Trahms L, Nickenig G, Fleischmann BK, Pfeifer A., Combined targeting of lentiviral vectors and positioning of transduced cells by magnetic nanoparticles. Proc Natl Acad Sci U S A. 2009; 106 (1): 44-9.
22. Liu B, Yu SF, Li TJ., Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts. J Oral Pathol Med. 2003; 32: 367-75.
23. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR., Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res. 1987; 2: 595-610.
24. Ivashkiv LB, Liou HC, Kara CJ, Lamph WW, Verma IM, Glimcher LH., mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element. Mol Cell Biol. 1990; 10: 1609-21.
25. Chatton B, Bocco JL, Goetz J, Gaire M, Lutz Y, Kedinger C., Jun and Fos heterodimerize with ATFa, a member of the ATF/CREB family and modulate its transcriptional activity. Oncogene. 1994; 9: 375-85.
26. Chatton B, Bahr A, Acker J, Kedinger C., Eukaryotic GST fusion vector for the study of protein-protein associations in vivo: application to interaction of ATFa with Jun and Fos. Biotechniques. 1995; 18: 142-5.
27. Gazit K, Moshonov S, Elfakess R, Sharon M, Mengus G, Davidson I, Dikstein R., TAF4/4b × TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes. J Biol Chem. 2009; 284: 26286-96.
28. Li XY, Boudjelal M, Xiao JH, Peng ZH, Asuru A, Kang S, Fisher GJ, Voorhees JJ., 1,25-Dihydroxyvitamin D3 increases nuclear vitamin D3 receptors by blocking ubiquitin/proteasome-mediated degradation in human skin. Mol Endocrinol. 1999; 13: 1686-94.
29. Hamard PJ, Boyer-Guittaut M, Camuzeaux B, Dujardin D, Hauss C, Oelgeschläger T, Vigneron M, Kedinger C, Chatton B., Sumoylation delays the ATF7 transcription factor subcellular localization and inhibits its transcriptional activity. Nucleic Acids Res. 2007; 35: 1134-44.