Triterpenoid saponins with anti-myocardial ischemia activity from the whole plants of Clematis tangutica

Planta Medica

Volumn 79, Issue 8, 2013, Pages 673-679

  Zhang, Wei ^a   Yao, Min Na ^a   Tang, Hai Feng ^a,b   Tian, Xiang Rong ^c   Wang, Min Chang ^d   Ji, Lan Ju ^e   Xi, Miao Miao ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c NORTHWEST A F UNIVERSITY   (China)

^d XI'AN MODERN CHEMISTRY RESEARCH INSTITUTE   (China)

^e Qinghai Yi Xin Pharmaceutical CoLtd   (China)

Author keywords

anti myocardial ischemia; Clematis tangutica; Ranunculaceae; triterpenoid saponin

Indexed keywords

CARDIOVASCULAR AGENT; CLEMATANGOSIDE A; CLEMATANGOSIDE B; CLEMATANGOSIDE C; CLEMATANGOSIDE D; CLEMATIS TANGUTICA EXTRACT; CREATINE KINASE MB; LACTATE DEHYDROGENASE; PLANT EXTRACT; SAPONIN DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG;

ARTICLE; CLEMATIS; CLEMATIS TANGUTICA; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; LACTATE DEHYDROGENASE BLOOD LEVEL; MEDICINAL PLANT; NONHUMAN;

CARBOHYDRATE CONFORMATION; CLEMATIS; MAGNETIC RESONANCE SPECTROSCOPY; MYOCARDIAL ISCHEMIA; SAPONINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRITERPENES;

CLEMATIS TANGUTICA; RANUNCULACEAE;

EID: 84878223386     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0032-1328541     Document Type: Article

References (27)

1. Deeks E. D., Keating G. M., Keam S. J. Clevidipine: a review of its use in the management of acute hypertension. Am J Cardiovasc Drugs: 2009; 9 117 134
2. Li C. M., Tian J. W., Li G. S., Jiang W. L., Xing Y. L., Hou J., Zhu H. B., Xu H., Zhang G. H., Liu Z. HF, Ye Z. G. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol: 2010; 649 100 107
3. Du Y., Ko K. M. Oleanolic acid protects against myocardial ischemia reperfusion injury by enhancing mitochondrial antioxidant mechanism mediated by glutathione and α -tocopherol in rats. Planta Med: 2006; 72 222 227
4. Northwest Plateau Institute of Biology, Academia Sinica. "Zang Yao Zhio" Xining Qinhai Peoples Press: 1991; 249
5. Zhong H. M., Chen C. X., Tian X., Chui Y. X., Chen Y. Z. Triterpenoid saponins from Clematis tangutica. Planta Med: 2001; 67 484 488 (Pubitemid 32652594)
6. Du Z. Z., Zhu N., Ze-Ren-Wang-Mu N., Shen Y. M. Two new antifungal saponins from the Tibetan herbal medicine Clematis tangutica. Planta Med: 2003; 69 547 551 (Pubitemid 36870631)
7. Wang X. Y., Chen X. L., Tang H. F., Gao H., Tian X. R., Zhang P. H. Cytotoxic triterpenoid saponins from the rhizomes of Anemone taipaiensis. Planta Med: 2011; 77 1550 1554
8. Hai W. L., Chen H., Zhao M., Wang Y., Hong L. J., Tang H. F., Tian X. R. Two new cytotoxic triterpenoid saponins from the roots of Clematis argentilucida. Fitoterapia: 2012; 83 759 764
9. Bi L. L., Tian X. R., Dou F., Hong L. J., Tang H. F., Wang S. W. New antioxidant and antiglycation active triterpenoid saponins from the root bark of Aralia taibaiensis. Fitoterapia: 2012; 83 234 240
10. Tian Y., Tang H. F., Qiu F., Wang X. J., Chen X. L., Wen A. D. Triterpenoid saponins from Ardisia pusilla and their cytotoxic activity. Planta Med: 2009; 75 70 75
11. De Marino S., Borbone N., Iorizzi M., Esposito G., McClintock J. B., Zollo F. Bioactive asterosaponins from the starfish Luidia quinaria and Psilaster cassiope, isolation and structure characterization by two-dimensional NMR spectroscopy. J Nat Prod: 2003; 66 515 519 (Pubitemid 36531900)
12. Nakano M., Knowlton A. A., Dibbs Z., Mann D. L. Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte. Circulation: 1998; 97 1392 1400 (Pubitemid 28182678)
13. Li P. C., Mak D. HF, Poon M. KT, Ip S. P., Ko K. M. Myocardial protective effect of Sheng Mai San (SMS) and a lignin-enriched extract of Fructus Schisandrae, in vivo and ex vivo. Phytomedicine: 1996; III 217 221 (Pubitemid 126491978)
14. Wang H. C., Zhang H. F., Guo W. Y., Su H., Zhang K. R., Li Q. X., Yan W. L., Ma X. L., Lopez B. L., Christopher T. A., Gao F. Hypoxic postconditioning enhances the survival and inhibits apoptosis of cardiomyocytes following reoxygenation: role of peroxynitrite formation. Apoptosis: 2006; 11 1453 1460 (Pubitemid 44035955)
15. Li X. C., Wang D. Z., Wu S. G., Yang C. R. Triterpenoid saponins from Pulsatilla campanella. Phytochemistry: 1990; 29 595 599
16. Jhoo JW, Sang SHM, He K, Cheng XF, Zhu NQ, Stark RE, Zheng QY, Rosen RT, Ho CHT. Characterization of the triterpene saponins of the roots and rhizomes of Blue Cohosh (Caulophyllum thalictroides). J Agric Food Chem: 2001; 49 5969 5974
17. Kizu H., Shimana H., Tomimori T. Studies on the constituents of Clematis species. VI. The constituents of Clematis stans Sieb. et Zucc. Chem Pharm Bull: 1995; 43 2187 2194 (Pubitemid 26018488)
18. Kawata Y., Kizu H., Miyaichi Y., Tomimori T. Studies on the constituents of Clematis species. VIII. Triterpenoid saponins from the aerial part of Clematis tibetana Kuntz. Chem Pharm Bull: 2001; 49 635 638 (Pubitemid 32505896)
19. Liao X., Chen Y. Z., Ding L. S., Li B. G. Chemical constituents from Anemone rupestris ssp gelida. Nat Prod Res Dev: 1999; 11 1 6
20. Kolno I., Tsboi A., Nanri M., Kawano N. Acylated triterpene glycoside from roots of Dipsacus asper. Phytochemistry: 1990; 29 338 339
21. Minaki Y., Watanabe K., Matsuo Y., Sakagami H. Triterpene glycosides from the tubers of Anemone coronaria. Chem Pharm Bull: 2009; 57 724 729
22. Meleka F. R., Miyaseb T., Abdel-Khalikc S. M., Hettaa M. H., Mahmoudc I. I. Triterpenoid saponins from Oreopanax guatemalensis. Phytochemistry: 2002; 60 185 195
23. Zheng Q., Koike K., Han L. K., Okuda H., Nikaido T. New biologically active triterpenoid saponins from Scabiosa tschiliensis. J Nat Prod: 2004; 67 604 613 (Pubitemid 38533932)
24. Mimaki Y., Yokosuka A., Hamanaka M., Sakuma C., Yamori T., Sashida Y. Triterpene saponins from the roots of Clematis chinensis. J Nat Prod: 2004; 67 1511 1516 (Pubitemid 39298619)
25. Romussi G., Falsone G. Inhaltsstoffe von Boraginaceae, 6. Mitt. anchusosid-4, ein neues Triterpensaponin aus Anchusa officinalis L. Arch Pharm: 1985; 318 219 221
26. Joshi B. S., Moore K. M., Pelletier S. W., Puar M. S., Pramanik B. N. Saponins from Collinsonia canadensis. J Nat Prod: 1992; 55 1468 1476
27. Kizu H., Tominori T. Studies on the constituents of Clematis Species. V. On the saponins of the root of Clematis chinensis OSBECK (5). Chem Pharm Bull: 1982; 30 3340 3346