IPOP goes the world: Integrated personalized omics profiling and the road toward improved health care

Chemistry and Biology

Volumn 20, Issue 5, 2013, Pages 660-666

  Li Pook Than, Jennifer ^a   Snyder, Michael ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; GENOMIC DNA; GLUCOSE; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METFORMIN; NOTCH RECEPTOR; PROTEOME; TRANSCRIPTOME;

BIOMICS; DIAGNOSTIC ACCURACY; DISEASE COURSE; DNA METHYLATION; DNA SEQUENCE; ENVIRONMENTAL FACTOR; EXOME; GENE FREQUENCY; GENETIC VARIABILITY; GENETICS; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HISTONE MODIFICATION; HUMAN; HUMAN RHINOVIRUS; INTEGRATED HEALTH CARE SYSTEM; INTEGRATED PERSONAL OMIC PROFILING; MEDICAL RESEARCH; METABOLOME; METAGENOME; MICROBIOME; NON INSULIN DEPENDENT DIABETES MELLITUS; PERSONALIZED MEDICINE; PHARMACOGENOMICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVIEW; RISK ASSESSMENT; RNA EDITING; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION;

ANIMALS; COMPUTATIONAL BIOLOGY; DNA; HUMANS; INDIVIDUALIZED MEDICINE; NEOPLASMS; PROTEOME; RNA;

EID: 84878218620     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.05.001     Document Type: Review

References (21)

1. G.R. Abecasis, D. Altshuler, A. Auton, L.D. Brooks, R.M. Durbin, R.A. Gibbs, M.E. Hurles, G.A. McVean 1000 Genomes Project Consortium A map of human genome variation from population-scale sequencing Nature 467 2010 1061 1073
2. E.A. Ashley, A.J. Butte, M.T. Wheeler, R. Chen, T.E. Klein, F.E. Dewey, J.T. Dudley, K.E. Ormond, A. Pavlovic, and A.A. Morgan Clinical assessment incorporating a personal genome Lancet 375 2010 1525 1535
3. G.W. Beadle, and E.L. Tatum Genetic control of biochemical reactions in Neurospora Proc. Natl. Acad. Sci. USA 27 1941 499 506
4. E. Birney, J.A. Stamatoyannopoulos, A. Dutta, R. Guigó, T.R. Gingeras, E.H. Margulies, Z. Weng, M. Snyder, E.T. Dermitzakis, R.E. Thurman ENCODE Project Consortium NISC Comparative Sequencing Program Baylor College of Medicine Human Genome Sequencing Center Washington University Genome Sequencing Center Broad Institute Children's Hospital Oakland Research Institute Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Nature 447 2007 799 816
5. A.P. Boyle, E.L. Hong, M. Hariharan, Y. Cheng, M.A. Schaub, M. Kasowski, K.J. Karczewski, J. Park, B.C. Hitz, and S. Weng Annotation of functional variation in personal genomes using RegulomeDB Genome Res. 22 2012 1790 1797
6. T. Cancer, G. Atlas Cancer Genome Atlas Research Network Integrated genomic analyses of ovarian carcinoma Nature 474 2011 609 615
7. R. Chen, G.I. Mias, J. Li-Pook-Than, L. Jiang, H.Y. Lam, R. Chen, E. Miriami, K.J. Karczewski, M. Hariharan, and F.E. Dewey Personal omics profiling reveals dynamic molecular and medical phenotypes Cell 148 2012 1293 1307
8. F. Crick Central dogma of molecular biology Nature 227 1970 561 563
9. S.J. Dawson, D.W. Tsui, M. Murtaza, H. Biggs, O.M. Rueda, S.F. Chin, M.J. Dunning, D. Gale, T. Forshew, and B. Mahler-Araujo Analysis of circulating tumor DNA to monitor metastatic breast cancer N. Engl. J. Med. 368 2013 1199 1209
10. R. de Sousa Abreu, L.O. Penalva, E.M. Marcotte, and C. Vogel Global signatures of protein and mRNA expression levels Mol. Biosyst. 5 2009 1512 1526
11. P. Flicek, M.R. Amode, D. Barrell, K. Beal, S. Brent, Y. Chen, P. Clapham, G. Coates, S. Fairley, and S. Fitzgerald Ensembl 2011 Nucleic Acids Res. 39 Database issue 2011 D800 D806
12. C. Genomics International Human Genome Sequencing Consortium Finishing the euchromatic sequence of the human genome Nature 431 2004 931 945
13. E.D. Green, M.S. Guyer National Human Genome Research Institute Charting a course for genomic medicine from base pairs to bedside Nature 470 2011 204 213
14. M. Krzywinski, J. Schein, I. Birol, J. Connors, R. Gascoyne, D. Horsman, S.J. Jones, and M.A. Marra Circos: an information aesthetic for comparative genomics Genome Res. 19 2009 1639 1645
15. J.B. Li, E.Y. Levanon, J.-K. Yoon, J. Aach, B. Xie, E. Leproust, K. Zhang, Y. Gao, and G.M. Church Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing Science 324 2009 1210 1213
16. D. McDonald, J.C. Clemente, J. Kuczynski, J.R. Rideout, J. Stombaugh, D. Wendel, A. Wilke, S. Huse, J. Hufnagle, and F. Meyer The Biological Observation Matrix (BIOM) format or: how I learned to stop worrying and love the ome-ome Gigascience 1 2012 7
17. R.A. Nafikov, J.P. Schoonmaker, K.T. Korn, K. Noack, D.J. Garrick, K.J. Koehler, J. Minick-Bormann, J.M. Reecy, D.E. Spurlock, and D.C. Beitz Sterol regulatory element binding transcription factor 1 (SREBF1) polymorphism and milk fatty acid composition J. Dairy Sci. 96 2013 2605 2616
18. G. Perkins, A. Lièvre, C. Ramacci, T. Méatchi, A. de Reynies, J.-F. Emile, V. Boige, G. Tomasic, J.B. Bachet, and F. Bibeau Additional value of EGFR downstream signaling phosphoprotein expression to KRAS status for response to anti-EGFR antibodies in colorectal cancer Int. J. Cancer 127 2010 1321 1331
19. G. Poste Bring on the biomarkers Nature 469 2011 156 157
20. G. Ramaswami, W. Lin, R. Piskol, M.H. Tan, C. Davis, and J.B. Li Accurate identification of human Alu and non-Alu RNA editing sites Nat. Methods 9 2012 579 581
21. M. Snyder, J. Du, and M. Gerstein Personal genome sequencing: current approaches and challenges Genes Dev. 24 2010 423 431