메뉴 건너뛰기




Volumn 36, Issue 5, 2013, Pages 295-302

Practical management of everolimus-related toxicities in patients with advanced solid tumors

Author keywords

Adverse event; Everolimus; Management; mTOR; Safety; Toxicity

Indexed keywords

ACICLOVIR; ANTIHISTAMINIC AGENT; CETYLPYRIDINIUM SALT; CORTICOSTEROID; ENTECAVIR; EVEROLIMUS; FLUCONAZOLE; METHYLPREDNISOLONE; MOUTHWASH; ORAL ANTIDIABETIC AGENT; PHOSPHATE; PREDNISOLONE; SORAFENIB; STREPSILS; TENOFOVIR; UNCLASSIFIED DRUG;

EID: 84878217451     PISSN: 0378584X     EISSN: 14230240     Source Type: Journal    
DOI: 10.1159/000350625     Document Type: Article
Times cited : (32)

References (46)
  • 1
    • 0036320205 scopus 로고    scopus 로고
    • Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake
    • Edinger AL, Thompson CB: Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol Biol Cell 2002;13: 2276-2288.
    • (2002) Mol Biol Cell , vol.13 , pp. 2276-2288
    • Edinger, A.L.1    Thompson, C.B.2
  • 2
    • 0036275356 scopus 로고    scopus 로고
    • Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling
    • Humar R, Kiefer FN, Berns H, Resink TJ, Battegay EJ: Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling. FASEB J 2002;16: 771-780.
    • (2002) FASEB J , vol.16 , pp. 771-780
    • Humar, R.1    Kiefer, F.N.2    Berns, H.3    Resink, T.J.4    Battegay, E.J.5
  • 3
    • 84859778293 scopus 로고    scopus 로고
    • MTOR signaling in growth control and disease
    • Laplante M, Sabatini DM: mTOR signaling in growth control and disease. Cell 2012;149: 274-293.
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 5
    • 63749097287 scopus 로고    scopus 로고
    • Optimal targeting of the mTORC1 kinase in human cancer
    • Lane HA, Breuleux M: Optimal targeting of the mTORC1 kinase in human cancer. Curr Opin Cell Biol 2009;21: 219-229.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 219-229
    • Lane, H.A.1    Breuleux, M.2
  • 6
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • Zoncu R, Efeyan A, Sabatini DM: mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 2011;12: 21-35.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 7
    • 84878231270 scopus 로고    scopus 로고
    • Afinitor® (everolimus) Tablets (package Insert). East Hanover NJ Novartis (accessed February 26, 2013)
    • Afinitor® (everolimus) tablets (package insert). East Hanover, NJ, Novartis, 2012. www.accessdata.fda.gov/drugsatfda-docs/label/2012/022334s018lbl. pdf (accessed February 26, 2013).
    • (2012)
  • 8
    • 84878218756 scopus 로고    scopus 로고
    • Afinitor® (everolimus) Tablets (summary Of Product Characteristics). Horsham UK Novartis Europharm Limited (accessed February 26, 2013)
    • Afinitor® (everolimus) tablets (summary of product characteristics). Horsham, UK, Novartis Europharm Limited, 2012. www.ema.europa.eu/docs/en-GB/ document-library/EPAR-Product-Information/human/001038/WC500022814.pdf (accessed February 26, 2013).
    • (2012)
  • 13
    • 84878246751 scopus 로고    scopus 로고
    • Votubia® (everolimus) Tablets (summary Of Product Characteristics). Horsham UK Novartis Europharm Limited (accessed February 26, 2013)
    • Votubia® (everolimus) tablets (summary of product characteristics). Horsham, UK, Novartis Europharm Limited, 2012. www.ema.europa.eu/docs/en-GB/ document-library/EPAR-Product-Information/human/002311/WC500112238.pdf (accessed February 26, 2013).
    • (2012)
  • 14
    • 83255167036 scopus 로고    scopus 로고
    • Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): A randomised, placebo-controlled, phase 3 study
    • Pavel ME, Hainsworth JD, Baudin E, Peeters M, Horsch D, Winkler RE, Klimovsky J, Lebwohl D, Jehl V, Wolin EM, Oberg K, Van Cutsem E, Yao JC: Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study. Lancet 2011;378: 2005-2012.
    • (2011) Lancet , vol.378 , pp. 2005-2012
    • Pavel, M.E.1    Hainsworth, J.D.2    Baudin, E.3    Peeters, M.4    Horsch, D.5    Winkler, R.E.6    Klimovsky, J.7    Lebwohl, D.8    Jehl, V.9    Wolin, E.M.10    Oberg, K.11    Van Cutsem, E.12    Yao, J.C.13
  • 15
    • 0035570382 scopus 로고    scopus 로고
    • Oral mucositis complicating chemotherapy and/or radiotherapy: Options for prevention and treatment
    • Kostler WJ, Hejna M, Wenzel C, Zielinski CC: Oral mucositis complicating chemotherapy and/or radiotherapy: options for prevention and treatment. CA Cancer J Clin 2001;51: 290-315.
    • (2001) CA Cancer J Clin , vol.51 , pp. 290-315
    • Kostler, W.J.1    Hejna, M.2    Wenzel, C.3    Zielinski, C.C.4
  • 17
    • 74549192779 scopus 로고    scopus 로고
    • Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients
    • Sonis S, Treister N, Chawla S, Demetri G, Haluska F: Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients. Cancer 2010;116: 210-215.
    • (2010) Cancer , vol.116 , pp. 210-215
    • Sonis, S.1    Treister, N.2    Chawla, S.3    Demetri, G.4    Haluska, F.5
  • 23
    • 33845385653 scopus 로고    scopus 로고
    • The effectiveness of commonly used mouthwashes for the prevention of chemotherapy- induced oral mucositis: A systematic review
    • Potting CM, Uitterhoeve R, Op Reimer WS, Van Achterberg T: The effectiveness of commonly used mouthwashes for the prevention of chemotherapy- induced oral mucositis: a systematic review. Eur J Cancer Care (Engl) 2006;15: 431-439.
    • (2006) Eur J Cancer Care (Engl) , vol.15 , pp. 431-439
    • Potting, C.M.1    Uitterhoeve, R.2    Op Reimer, W.S.3    Van Achterberg, T.4
  • 24
    • 33748053644 scopus 로고    scopus 로고
    • Preventive intervention possibilities in radiotherapyand chemotherapy-induced oral mucositis: Results of meta-analyses
    • Stokman MA, Spijkervet FK, Boezen HM, Schouten JP, Roodenburg JL, de Vries EG: Preventive intervention possibilities in radiotherapyand chemotherapy-induced oral mucositis: results of meta-analyses. J Dent Res 2006;85: 690-700.
    • (2006) J Dent Res , vol.85 , pp. 690-700
    • Stokman, M.A.1    Spijkervet, F.K.2    Boezen, H.M.3    Schouten, J.P.4    Roodenburg, J.L.5    De Vries, E.G.6
  • 25
    • 70450190946 scopus 로고    scopus 로고
    • Ketamine mouthwash for mucositis pain
    • Ryan AJ, Lin F, Atayee RS: Ketamine mouthwash for mucositis pain. J Palliat Med 2009;12: 989-991.
    • (2009) J Palliat Med , vol.12 , pp. 989-991
    • Ryan, A.J.1    Lin, F.2    Atayee, R.S.3
  • 27
    • 33847743084 scopus 로고    scopus 로고
    • Clobetasol ameliorates aphthous ulceration in renal transplant patients on sirolimus
    • Chuang P, Langone AJ: Clobetasol ameliorates aphthous ulceration in renal transplant patients on sirolimus. Am J Transplant 2007;7: 714-717.
    • (2007) Am J Transplant , vol.7 , pp. 714-717
    • Chuang, P.1    Langone, A.J.2
  • 28
    • 33846866035 scopus 로고    scopus 로고
    • The role of mammalian target of rapamycin inhibitors in the treatment of advanced renal cancer
    • Cho D, Signoretti S, Regan M, Mier JW, Atkins MB: The role of mammalian target of rapamycin inhibitors in the treatment of advanced renal cancer. Clin Cancer Res 2007;13: 758s-763s.
    • (2007) Clin Cancer Res , vol.13
    • Cho, D.1    Signoretti, S.2    Regan, M.3    Mier, J.W.4    Atkins, M.B.5
  • 30
    • 84864954263 scopus 로고    scopus 로고
    • Incidence and management of mTOR inhibitor-associated pneumonitis in patients with metastatic renal cell carcinoma
    • Albiges L, Chamming's F, Duclos B, Stern M, Motzer RJ, Ravaud A, Camus P: Incidence and management of mTOR inhibitor-associated pneumonitis in patients with metastatic renal cell carcinoma. Ann Oncol 2012;23: 1943-1953.
    • (2012) Ann Oncol , vol.23 , pp. 1943-1953
    • Albiges, L.1    Chamming'S, F.2    Duclos, B.3    Stern, M.4    Motzer, R.J.5    Ravaud, A.6    Camus, P.7
  • 32
    • 77953407754 scopus 로고    scopus 로고
    • Everolimus - A new approach in the treatment of renal cell carcinoma
    • Anandappa G, Hollingdale A, Eisen T: Everolimus - a new approach in the treatment of renal cell carcinoma. Cancer Manag Res 2010;2: 61-70.
    • (2010) Cancer Manag Res , vol.2 , pp. 61-70
    • Anandappa, G.1    Hollingdale, A.2    Eisen, T.3
  • 33
    • 79953125363 scopus 로고    scopus 로고
    • Noninfectious pneumonitis in a patient with renal cell carcinoma treated with everolimus
    • Creel P, Moldawer NP: Noninfectious pneumonitis in a patient with renal cell carcinoma treated with everolimus. Oncol Nurs Forum 2011;38: 125-128.
    • (2011) Oncol Nurs Forum , vol.38 , pp. 125-128
    • Creel, P.1    Moldawer, N.P.2
  • 35
    • 84878220426 scopus 로고    scopus 로고
    • Management of key adverse events associated with everolimus therapy
    • Moldawer NP, Wood LS: Management of key adverse events associated with everolimus therapy. Kidney Cancer J 2010;8: 51-59.
    • (2010) Kidney Cancer J , vol.8 , pp. 51-59
    • Moldawer, N.P.1    Wood, L.S.2
  • 37
    • 77951282223 scopus 로고    scopus 로고
    • Emergent toxicities associated with the use of mTOR inhibitors in patients with advanced renal carcinoma
    • Rodriguez-Pascual J, Cheng E, Maroto P, Duran I: Emergent toxicities associated with the use of mTOR inhibitors in patients with advanced renal carcinoma. Anticancer Drugs 2010;21: 478-486.
    • (2010) Anticancer Drugs , vol.21 , pp. 478-486
    • Rodriguez-Pascual, J.1    Cheng, E.2    Maroto, P.3    Duran, I.4
  • 38
    • 0344752564 scopus 로고    scopus 로고
    • Self-monitoring of blood glucose: The basics
    • Benjamin EM: Self-monitoring of blood glucose: the basics. Clinical Diabetes 2002;20: 45-47.
    • (2002) Clinical Diabetes , vol.20 , pp. 45-47
    • Benjamin, E.M.1
  • 39
    • 60449089649 scopus 로고    scopus 로고
    • Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B: Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009;32: 193-203.
    • (2009) Diabetes Care , vol.32 , pp. 193-203
    • Nathan, D.M.1    Buse, J.B.2    Davidson, M.B.3    Ferrannini, E.4    Holman, R.R.5    Sherwin, R.6    Zinman, B.7
  • 41
    • 72649093760 scopus 로고    scopus 로고
    • Severe hypertriglyceridemia and pancreatitis: Presentation and management
    • Ewald N, Hardt PD, Kloer HU: Severe hypertriglyceridemia and pancreatitis: presentation and management. Curr Opin Lipidol 2009;20: 497-504.
    • (2009) Curr Opin Lipidol , vol.20 , pp. 497-504
    • Ewald, N.1    Hardt, P.D.2    Kloer, H.U.3
  • 43
    • 84878894251 scopus 로고    scopus 로고
    • International task force for prevention of coronary heart disease
    • International task force for prevention of coronary heart disease. Treatment guidelines for dyslipidemia. www.chd-taskforce.com/pdf/2004-06-09- zurich. pdf.
    • Treatment Guidelines for Dyslipidemia
  • 44
    • 0242490858 scopus 로고    scopus 로고
    • Recommendations for the management of dyslipidemia and the prevention of cardiovascular disease: Summary of the 2003 update
    • Genest J, Frohlich J, Fodor G, McPherson R: Recommendations for the management of dyslipidemia and the prevention of cardiovascular disease: summary of the 2003 update. CMAJ 2003; 169: 921-924.
    • (2003) CMAJ , vol.169 , pp. 921-924
    • Genest, J.1    Frohlich, J.2    Fodor, G.3    McPherson, R.4
  • 45
    • 74549205409 scopus 로고    scopus 로고
    • Management of sorafenib, sunitinib, and temsirolimus toxicity in metastatic renal cell carcinoma
    • Guevremont C, Alasker A, Karakiewicz PI: Management of sorafenib, sunitinib, and temsirolimus toxicity in metastatic renal cell carcinoma. Curr Opin Support Palliat Care 2009;3: 170-179.
    • (2009) Curr Opin Support Palliat Care , vol.3 , pp. 170-179
    • Guevremont, C.1    Alasker, A.2    Karakiewicz, P.I.3
  • 46
    • 58149296156 scopus 로고    scopus 로고
    • EASL Clinical Practice Guidelines: Management of chronic hepatitis B
    • EASL Clinical Practice Guidelines: management of chronic hepatitis B. J Hepatol 2009;50: 227-242.
    • (2009) J Hepatol , vol.50 , pp. 227-242


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.