Proper Indication of BRAFV600E Mutation Testing in Fine-Needle Aspirates of Thyroid Nodules

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Koh, Jieun ^a   Choi, Jong Rak ^a   Han, Kyung Hwa ^a   Kim, Eun Kyung ^a   Yoon, Jung Hyun ^a   Moon, Hee Jung ^a   Kwak, Jin Young ^a  

^a Yonsei University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; GLUTAMIC ACID; VALINE; BRAF PROTEIN, HUMAN;

ADULT; AGE DISTRIBUTION; ARTICLE; CLINICAL EVALUATION; CLINICAL FEATURE; CYTODIAGNOSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FINE NEEDLE ASPIRATION BIOPSY; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MUTATIONAL ANALYSIS; PREDICTIVE VALUE; SENSITIVITY AND SPECIFICITY; THYROID CANCER; THYROID NODULE; TUMOR VOLUME; ENDOSCOPIC ULTRASOUND GUIDED FINE NEEDLE BIOPSY; GENETICS; MIDDLE AGED; MUTATION; PATHOLOGY; REPRODUCIBILITY;

ADULT; ENDOSCOPIC ULTRASOUND-GUIDED FINE NEEDLE ASPIRATION; HUMANS; MIDDLE AGED; MUTATION; PROTO-ONCOGENE PROTEINS B-RAF; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THYROID NODULE;

EID: 84878143524     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064505     Document Type: Article

References (31)

1. Xing M, (2007) BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical implications. Endocr Rev 28: 742-762.
2. Nikiforov YE, Nikiforova MN, (2011) Molecular genetics and diagnosis of thyroid cancer. Nat Rev Endocrinol 7: 569-580.
3. Nikiforov YE, Ohori NP, Hodak SP, Carty SE, LeBeau SO, et al. (2011) Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA samples. J Clin Endocrinol Metab 96: 3390-3397.
4. Hwang J, Shin JH, Han BK, Ko EY, Kang SS, et al. (2010) Papillary thyroid carcinoma with BRAFV600E mutation: sonographic prediction. AJR Am J Roentgenol 194: W425-430.
5. Lee ST, Kim SW, Ki CS, Jang JH, Shin JH, et al. (2012) Clinical implication of highly sensitive detection of the BRAF V600E mutation in fine-needle aspirations of thyroid nodules: a comparative analysis of three molecular assays in 4585 consecutive cases in a BRAF V600E mutation-prevalent area. J Clin Endocrinol Metab 97: 2299-2306.
6. Ahn D, Park JS, Sohn JH, Kim JH, Park SK, et al. (2012) BRAFV600E mutation does not serve as a prognostic factor in Korean patients with papillary thyroid carcinoma. Auris Nasus Larynx 39: 198-203.
7. Yeo MK, Liang ZL, Oh T, Moon Y, An S, et al. (2011) Pyrosequencing cut-off value identifying BRAF(V600E) mutation in fine needle aspiration samples of thyroid nodules. Clin Endocrinol (Oxf) 75: 555-560.
8. Kim SK, Hwang TS, Yoo YB, Han HS, Kim DL, et al. (2011) Surgical results of thyroid nodules according to a management guideline based on the BRAF(V600E) mutation status. J Clin Endocrinol Metab 96: 658-664.
9. Moon HJ, Kim EK, Chung WY, Choi JR, Yoon JH, et al. (2011) Diagnostic value of BRAF(V600E) mutation analysis of thyroid nodules according to ultrasonographic features and the time of aspiration. Ann Surg Oncol 18: 792-799.
10. Kim SW, Lee JI, Kim JW, Ki CS, Oh YL, et al. (2010) BRAFV600E mutation analysis in fine-needle aspiration cytology specimens for evaluation of thyroid nodule: a large series in a BRAFV600E-prevalent population. J Clin Endocrinol Metab 95: 3693-3700.
11. Lee EJ, Song KH, Kim DL, Jang YM, Hwang TS, et al. (2011) The BRAF(V600E) mutation is associated with malignant ultrasonographic features in thyroid nodules. Clin Endocrinol (Oxf) 75: 844-850.
12. Nam SY, Han BK, Ko EY, Kang SS, Hahn SY, et al. (2010) BRAF V600E mutation analysis of thyroid nodules needle aspirates in relation to their ultrasongraphic classification: a potential guide for selection of samples for molecular analysis. Thyroid 20: 273-279.
13. Kwak JY, Kim EK, Chung WY, Moon HJ, Kim MJ, et al. (2009) Association of BRAFV600E mutation with poor clinical prognostic factors and US features in Korean patients with papillary thyroid microcarcinoma. Radiology 253: 854-860.
14. Kwak JY, Kim EK, Kim JK, Han JH, Hong SW, et al. (2010) Dual priming oligonucleotide-based multiplex PCR analysis for detection of BRAFV600E mutation in FNAB samples of thyroid nodules in BRAFV600E mutation-prevalent area. Head Neck 32: 490-498.
15. Kim TY, Kim WB, Rhee YS, Song JY, Kim JM, et al. (2006) The BRAF mutation is useful for prediction of clinical recurrence in low-risk patients with conventional papillary thyroid carcinoma. Clin Endocrinol (Oxf) 65: 364-368.
16. Kim EK, Park CS, Chung WY, Oh KK, Kim DI, et al. (2002) New sonographic criteria for recommending fine-needle aspiration biopsy of nonpalpable solid nodules of the thyroid. AJR Am J Roentgenol 178: 687-691.
17. Cibas ES, Ali SZ, (2009) The Bethesda System for Reporting Thyroid Cytopathology. Thyroid 19: 1159-1165.
18. Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, et al. (2009) Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 19: 1167-1214.
19. Lee MJ, Hong SW, Chung WY, Kwak JY, Kim MJ, et al. (2011) Cytological results of ultrasound-guided fine-needle aspiration cytology for thyroid nodules: emphasis on correlation with sonographic findings. Yonsei Med J 52: 838-844.
20. Wang CC, Friedman L, Kennedy GC, Wang H, Kebebew E, et al. (2011) A large multicenter correlation study of thyroid nodule cytopathology and histopathology. Thyroid 21: 243-251.
21. Hamfjord J, Stangeland AM, Skrede ML, Tveit KM, Ikdahl T, et al. (2011) Wobble-enhanced ARMS method for detection of KRAS and BRAF mutations. Diagn Mol Pathol 20: 158-165.
22. Tonacchera M, Agretti P, Rago T, De Marco G, Niccolai F, et al. (2012) Genetic markers to discriminate benign and malignant thyroid nodules with undetermined cytology in an area of borderline iodine deficiency. J Endocrinol Invest 35: 754-759.
23. Nikiforov YE, Steward DL, Robinson-Smith TM, Haugen BR, Klopper JP, et al. (2009) Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules. J Clin Endocrinol Metab 94: 2092-2098.
24. Ohori NP, Singhal R, Nikiforova MN, Yip L, Schoedel KE, et al. (2012) BRAF mutation detection in indeterminate thyroid cytology specimens: Underlying cytologic, molecular, and pathologic characteristics of papillary thyroid carcinoma. Cancer Cytopathol.
25. Adeniran AJ, Theoharis C, Hui P, Prasad ML, Hammers L, et al. (2011) Reflex BRAF testing in thyroid fine-needle aspiration biopsy with equivocal and positive interpretation: a prospective study. Thyroid 21: 717-723.
26. Hassell LA, Gillies EM, Dunn ST, (2012) Cytologic and molecular diagnosis of thyroid cancers: is it time for routine reflex testing? Cancer Cytopathol 120: 7-17.
27. Kwak JY, Koo H, Youk JH, Kim MJ, Moon HJ, et al. (2010) Value of US correlation of a thyroid nodule with initially benign cytologic results. Radiology 254: 292-300.
28. Gharib H, Goellner JR, (1993) Fine-needle aspiration biopsy of the thyroid: an appraisal. Ann Intern Med 118: 282-289.
29. Park SH, Kim SJ, Kim EK, Kim MJ, Son EJ, et al. (2009) Interobserver agreement in assessing the sonographic and elastographic features of malignant thyroid nodules. AJR Am J Roentgenol 193: W416-423.
30. Kim SH, Park CS, Jung SL, Kang BJ, Kim JY, et al. (2010) Observer Variability and the Performance between Faculties and Residents: US Criteria for Benign and Malignant Thyroid Nodules. Korean J Radiol 11: 149-155.
31. Choi SH, Kim EK, Kwak JY, Kim MJ, Son EJ, (2010) Interobserver and intraobserver variations in ultrasound assessment of thyroid nodules. Thyroid 20: 167-172.