Methylated arginines and nitric oxide in end-stage renal disease: Impact of inflammation, oxidative stress and haemodialysis

Biomarkers

Volumn 18, Issue 4, 2013, Pages 357-364

  Bouteldja, Nadia ^a   Woodman, Richard J ^b   Hewitson, Chris L ^b   Domingo, Enric ^a,c   Barbara, Jeffrey A ^d   Mangoni, Arduino A ^b  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b FLINDERS UNIVERSITY   (Australia)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^d FLINDERS MEDICAL CENTRE   (Australia)

Author keywords

Cardiovascular disease; Metabol(n)omics; Renal disease

Indexed keywords

C REACTIVE PROTEIN; MALONALDEHYDE; N(G) METHYLARGININE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE;

ADULT; AGED; AMINO ACID BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; FEMALE; HEMODIALYSIS; HUMAN; INFLAMMATION; KIDNEY FAILURE; MALE; METABOLITE; METHYLATION; OXIDATIVE STRESS;

AGED; ARGININE; BIOLOGICAL MARKERS; FEMALE; HUMANS; INFLAMMATION; KIDNEY FAILURE, CHRONIC; MALE; METHYLATION; MIDDLE AGED; NITRIC OXIDE; OXIDATIVE STRESS; RENAL DIALYSIS;

EID: 84878117446     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.3109/1354750X.2013.795608     Document Type: Article

References (46)

1. Annuk M, Zilmer M, Lind L, et al. (2001). Oxidative stress and endothelial function in chronic renal failure. J Am Soc Nephrol 12: 2747-52 (Pubitemid 33115422)
2. Aucella F, Maas R, Vigilante M, et al. (2009). Methylarginines and mortality in patients with end stage renal disease: A prospective cohort study. Atherosclerosis 207:541-5
3. Baylis C. (2006). Arginine, arginine analogs and nitric oxide production in chronic kidney disease. Nat Clin Pract Nephrol 2:209-20 (Pubitemid 43787287)
4. Bode-Boger SM, Scalera F, Kielstein JT, et al. (2006). Symmetrical dimethylarginine: A new combined parameter for renal function and extent of coronary artery disease. J Am Soc Nephrol 17:1128-34
5. Boger RH, Endres HG, Schwedhelm E, et al. (2011). Asymmetric dimethylarginine as an independent risk marker for mortality in ambulatory patients with peripheral arterial disease. J Intern Med 269: 349-61
6. Cavusoglu E, Ruwende C, Chopra V, et al. (2010). Relation of baseline plasma ADMA levels to cardiovascular morbidity and mortality at two years in men with diabetes mellitus referred for coronary angiography. Atherosclerosis 210:226-31
7. Ceballos-Picot I, Witko-Sarsat V, Merad-Boudia M, et al. (1996). Glutathione antioxidant system as a marker of oxidative stress in chronic renal failure. Free Radic Biol Med 21:845-53 (Pubitemid 26365280)
8. Closs EI, Basha FZ, Habermeier A, Forstermann U. (1997). Interference of L-arginine analogues with L-arginine transport mediated by the y carrier hCAT-2B. Nitric Oxide 1:65-73 (Pubitemid 28078129)
9. Druhan LJ, Forbes SP, Pope AJ, et al. (2008). Regulation of eNOSderived superoxide by endogenous methylarginines. Biochemistry 47: 7256-63 (Pubitemid 351956374)
10. Forstermann U. (2010). Nitric oxide and oxidative stress in vascular disease. Pflugers Arch 459:923-39
11. Galli F. (2007). Protein damage and inflammation in uraemia and dialysis patients. Nephrol Dial Transplant 22:v20-36
12. Hewitson CL, Whiting MJ, Barbara JA, et al. (2007). Acute effects of haemodialysis on biochemical modulators of endothelial function. J Intern Med 262:571-80 (Pubitemid 47620505)
13. Khaper N, Bryan S, Dhingra S, et al. (2010). Targeting the vicious inflammation-oxidative stress cycle for the management of heart failure. Antioxid Redox Signal 13:1033-49
14. Kielstein JT, Salpeter SR, Bode-Boeger SM, et al. (2006). Symmetric dimethylarginine (SDMA) as endogenous marker of renal function - a meta-analysis. Nephrol Dial Transplant 21:2446-51 (Pubitemid 44644516)
15. Landmesser U, Dikalov S, Price SR, et al. (2003). Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest 111:1201-9 (Pubitemid 36519937)
16. Leiper J, Murray-Rust J, McDonald N, Vallance P. (2002). S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: Further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase. Proc Natl Acad Sci USA 99:13527-32 (Pubitemid 35215415)
17. Lluch P, Torondel B, Medina P, et al. (2004). Plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis. J Hepatol 41:55-9 (Pubitemid 39005153)
18. Locatelli F, Canaud B, Eckardt KU, et al. (2003). Oxidative stress in endstage renal disease: An emerging threat to patient outcome. Nephrol Dial Transplant 18:1272-80 (Pubitemid 36826946)
19. MacAllister RJ, Whitley GS, Vallance P. (1994). Effects of guanidino and uremic compounds on nitric oxide pathways. Kidney Int 45: 737-42 (Pubitemid 24094485)
20. Martens CR, Edwards DG. (2011). Peripheral vascular dysfunction in chronic kidney disease. Cardiol Res Pract 2011:267257
21. Meinitzer A, Kielstein JT, Pilz S, et al. (2011). Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: The Ludwigshafen Risk and Cardiovascular Health study. Clin Chem 57:112-21
22. Mimic-Oka J, Simic T, Djukanovic L, et al. (1999). Alteration in plasma antioxidant capacity in various degrees of chronic renal failure. Clin Nephrol 51:233-41 (Pubitemid 29196887)
23. Moshage H, Kok B, Huizenga JR, Jansen PL. (1995). Nitrite and nitrate determinations in plasma: A critical evaluation. Clin Chem 41:892-6
24. Nguyen-Khoa T, Massy ZA, De Bandt JP, et al. (2001). Oxidative stress and haemodialysis: Role of inflammation and duration of dialysis treatment. Nephrol Dial Transplant 16:335-40 (Pubitemid 32123923)
25. Nielsen F, Mikkelsen BB, Nielsen JB, et al. (1997). Plasma malondialdehyde as biomarker for oxidative stress: Reference interval and effects of life-style factors. Clin Chem 43:1209-14 (Pubitemid 27297265)
26. Nijveldt RJ, Van Leeuwen PA, Van Guldener C, et al. (2002). Net renal extraction of asymmetrical (ADMA) and symmetrical (SDMA) dimethylarginine in fasting humans. Nephrol Dial Transplant 17: 1999-2002 (Pubitemid 35277101)
27. Oner-Iyidogan Y, Oner P, Kocak H, et al. (2009). Dimethylarginines and inflammation markers in patients with chronic kidney disease undergoing dialysis. Clin Exp Med 9:235-41
28. Otsuji S, Shibata H, Umeda M. (1982). Turbidimetric immunoassay of serum C-reactive protein. Clin Chem 28:2121-4 (Pubitemid 12034063)
29. Pitocco D, Zaccardi F, Di Stasio E, et al. (2009). Role of asymmetricdimethyl- L-arginine (ADMA) and nitrite/nitrate (NOx) in the pathogenesis of oxidative stress in female subjects with uncomplicated type 1 diabetes mellitus. Diabetes Res Clin Pract 86:173-6
30. Pope AJ, Druhan L, Guzman JE, et al. (2007). Role of DDAH-1 in lipid peroxidation product-mediated inhibition of endothelial NO generation. Am J Physiol Cell Physiol 293:C1679-86 (Pubitemid 350085638)
31. Powell LA, Nally SM, McMaster D, et al. (2001). Restoration of glutathione levels in vascular smooth muscle cells exposed to high glucose conditions. Free Radic Biol Med 31:1149-55 (Pubitemid 33052489)
32. Pryor WA, Squadrito GL. (1995). The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide. Am J Physiol 268:L699-722
33. Raj DS, Vincent B, Simpson K, et al. (2002). Hemodynamic changes during hemodialysis: Role of nitric oxide and endothelin. Kidney Int 61:697-704 (Pubitemid 34102613)
34. Schalkwijk CG, Poland DC, van Dijk W, et al. (1999). Plasma concentration of C-reactive protein is increased in type I diabetic patients without clinical macroangiopathy and correlates with markers of endothelial dysfunction: Evidence for chronic inflammation. Diabetologia 42:351-7 (Pubitemid 29111443)
35. Schepers E, Glorieux G, Dhondt A, et al. (2009). Role of symmetric dimethylarginine in vascular damage by increasing ROS via storeoperated calcium influx in monocytes. Nephrol Dial Transplant 24: 1429-35
36. Schmidt RJ, Domico J, Samsell LS, et al. (1999). Indices of activity of the nitric oxide system in hemodialysis patients. Am J Kidney Dis 34: 228-34 (Pubitemid 29362085)
37. Schulze F, Carter AM, Schwedhelm E, et al. (2010). Symmetric dimethylarginine predicts all-cause mortality following ischemic stroke. Atherosclerosis 208:518-23
38. Schwedhelm E, Tan-Andresen J, Maas R, et al. (2005). Liquid chromatography-tandem mass spectrometry method for the analysis of asymmetric dimethylarginine in human plasma. Clin Chem 51: 1268-71 (Pubitemid 43079411)
39. Thuraisingham RC, Roberts NB, Wilkes M, et al. (2002). Altered L-arginine metabolism results in increased nitric oxide release from uraemic endothelial cells. Clin Sci (Lond) 103:31-41 (Pubitemid 34729122)
40. Tripepi G, Mattace RF, Sijbrands E, et al. (2011). Inflammation and asymmetric dimethylarginine for predicting death and cardiovascular events in ESRD patients. Clin J Am Soc Nephrol 6:1714-21
41. Usui M, Matsuoka H, Miyazaki H, et al. (1998). Increased endogenous nitric oxide synthase inhibitor in patients with congestive heart failure. Life Sci 62:2425-30 (Pubitemid 28273149)
42. Vallance P, Leiper J. (2004). Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway. Arterioscler Thromb Vasc Biol 24:1023-30 (Pubitemid 38737826)
43. Vallance P, Leone A, Calver A, et al. (1992). Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 339:572-5
44. White M, Ducharme A, Ibrahim R, et al. (2006). Increased systemic inflammation and oxidative stress in patients with worsening congestive heart failure: Improvement after short-term inotropic support. Clin Sci (Lond) 110:483-9
45. Woodman RJ. (2008). Does compensatory nitric oxide and angiotensin II receptor activity reduce arterial stiffness in early-stage insulin resistance? Clin Sci (Lond) 114:119-21
46. Zoccali C, Benedetto FA, Maas R, et al. (2002). Asymmetric dimethylarginine, C-reactive protein, and carotid intima-media thickness in end-stage renal disease. J Am Soc Nephrol 13:490-6. (Pubitemid 34106292)