Use of a massive transfusion protocol in nontrauma patients: Activate away

Journal of the American College of Surgeons

Volumn 216, Issue 6, 2013, Pages 1103-1109

  McDaniel, Lauren M ^a   Neal, Matthew D ^a   Sperry, Jason L ^a   Alarcon, Louis H ^a   Forsythe, Raquel M ^a   Triulzi, Darrell ^b,c   Peitzman, Andrew B ^a   Raval, Jay S ^d  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c INSTITUTE FOR TRANSFUSION MEDICINE   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

FFP; fresh frozen plasma; general medical surgical; GMS; massive transfusion protocol; MTP; packed red blood cells; platelet; PLT; PRBC

Indexed keywords

FRESH FROZEN PLASMA;

ADULT; ARTICLE; BLOOD BANK; BLOOD TRANSFUSION; CLINICAL PROTOCOL; CONTROLLED STUDY; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMAN; INJURY; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RESOURCE ALLOCATION; RESUSCITATION; RETROSPECTIVE STUDY; THROMBOCYTE TRANSFUSION;

ADULT; BLOOD TRANSFUSION; FEMALE; HEMORRHAGE; HUMANS; MALE; MIDDLE AGED; RESUSCITATION; RETROSPECTIVE STUDIES; SURVIVAL RATE; UNITED STATES; WOUNDS AND INJURIES;

EID: 84878106663     PISSN: 10727515     EISSN: 18791190     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2013.02.008     Document Type: Article

References (21)

1. A. Hirshberg, M. Dugas, and E.I. Banez Minimizing dilutional coagulopathy in exsanguinating hemorrhage: a computer simulation J Trauma 54 2003 454 463 (Pubitemid 36383741)
2. J.B. Holcomb, C.E. Wade, and J.E. Michalek Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients Ann Surg 248 2008 447 458
3. J.B. Holcomb, L.A. Zarzabal, and J.E. Michalek Increased platelet:RBC ratios are associated with improved survival after massive transfusion J Trauma 71 Suppl 3 2011 S318 S328
4. J.L. Sperry, J.B. Ochoa, and S.R. Gunn An FFP: PRBC transfusion ratio >/ = 1:1.5 is associated with a lower risk of mortality after massive transfusion J Trauma 65 2008 986 993
5. K.A. Zink, C.N. Sambasivan, and J.B. Holcomb A high ratio of plasma and platelets to packed red blood cells in the first 6 hours of massive transfusion improves outcomes in a large multicenter study Am J Surg 197 2009 565 570 discussion 570
6. E.A. Gonzalez, F.A. Moore, and J.B. Holcomb Fresh frozen plasma should be given earlier to patients requiring massive transfusion J Trauma 62 2007 112 119 (Pubitemid 46102840)
7. M.D. Neal, A. Marsh, and R. Marino Massive transfusion: an evidence-based review of recent developments Arch Surg 147 2012 563 571
8. M.D. Neal, M.K. Hoffman, and J. Cuschieri Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: when a little goes a long way J Trauma Acute Care Surg 72 2012 892 898
9. B.A. Cotton, B.K. Au, and T.C. Nunez Predefined massive transfusion protocols are associated with a reduction in organ failure and postinjury complications J Trauma 66 2009 41 48 discussion 48-49
10. B.A. Cotton, O.L. Gunter, and J. Isbell Damage control hematology: the impact of a trauma exsanguination protocol on survival and blood product utilization J Trauma 64 2008 1177 1182 discussion 1182-1183 (Pubitemid 351671208)
11. C.J. Dente, B.H. Shaz, and J.M. Nicholas Improvements in early mortality and coagulopathy are sustained better in patients with blunt trauma after institution of a massive transfusion protocol in a civilian level I trauma center J Trauma 66 2009 1616 1624
12. T. O'Keeffe, M. Refaai, and K. Tchorz A massive transfusion protocol to decrease blood component use and costs Arch Surg 143 2008 686 690 discussion 690-691 (Pubitemid 352040242)
13. D.J. Riskin, T.C. Tsai, and L. Riskin Massive transfusion protocols: the role of aggressive resuscitation versus product ratio in mortality reduction J Am Coll Surg 209 2009 198 205
14. A. Ciccocioppo, M. Walker, and F. Taylor Protocol management for patients presenting with lower GI haemorrhage saves costs and maintains outcomes ANZ J Surg 81 2011 451 455
15. M. Burtelow, E. Riley, and M. Druzin How we treat: management of life-threatening primary postpartum hemorrhage with a standardized massive transfusion protocol Transfusion 47 2007 1564 1572 (Pubitemid 47300625)
16. M.C. Gutierrez, L.T. Goodnough, M. Druzin, and A.J. Butwick Postpartum hemorrhage treated with a massive transfusion protocol at a tertiary obstetric center: a retrospective study Int J Obstet Anesth 21 2012 230 235
17. B.C. Morse, C.J. Dente, and E.I. Hodgman Outcomes after massive transfusion in nontrauma patients in the era of damage control resuscitation Am Surg 78 2012 679 684
18. C.J. Dente, B.H. Shaz, and J.M. Nicholas Early predictors of massive transfusion in patients sustaining torso gunshot wounds in a civilian level I trauma center J Trauma 68 2010 298 304
19. T.C. Nunez, I.V. Voskresensky, and L.A. Dossett Early prediction of massive transfusion in trauma: simple as ABC (assessment of blood consumption)? J Trauma 66 2009 346 352
20. N. Yucel, R. Lefering, and M. Maegele Trauma Associated Severe Hemorrhage (TASH)-score: probability of mass transfusion as surrogate for life threatening hemorrhage after multiple trauma J Trauma 60 2006 1228 1236 discussion 1236-1237
21. B.A. Cotton, L.A. Dossett, and B.K. Au Room for (performance) improvement: provider-related factors associated with poor outcomes in massive transfusion J Trauma 67 2009 1004 1012