-
1
-
-
84943764417
-
-
[accessed 2012 Jul 19]
-
The Nobel Prize in Physiology or Medicine 1950. Nobelprize.org [accessed 2012 Jul 19]. Available from: http://www.nobelprize.org/nobel-prizes/medicine/ laureates/1950/
-
(1950)
The Nobel Prize in Physiology or Medicine
-
-
-
2
-
-
84878087844
-
-
Lewis Hastings Sarett. December 22. -November 29, 1999. The National Academies Press. [accessed 2012 Jul 19]. Available from: http://www.nap.edu/ readingroom/books/biomems/lsarett.html
-
Lewis Hastings Sarett. December 22, 1917-November 29, 1999. The National Academies Press (http://www.nap.edu/readingroom/books/biomems/lsarett.htm) 2012 [accessed 2012 Jul 19]. Available from: http://www.nap.edu/readingroom/books/ biomems/lsarett.html.
-
(1917)
-
-
-
3
-
-
84943764417
-
-
[accessed 2012 Jul 19]
-
The Nobel Prize in Physiology or Medicine 1952. Nobelprize.org [accessed 2012 Jul 19]. Available from: http://www.nobelprize.org/nobel-prizes/medicine/ laureates/1952/
-
(1952)
The Nobel Prize in Physiology or Medicine
-
-
-
4
-
-
0033612867
-
A change in scientific approach: From alternation to randomised allocation in clinical trials in the 1940s
-
Hart PD. A change in scientific approach: from alternation to randomised allocation in clinical trials in the 1940s. BMJ 1999;319:572-573.
-
(1999)
BMJ
, vol.319
, pp. 572-573
-
-
Hart, P.D.1
-
5
-
-
84855513894
-
-
New York, NY: Simon & Schuster
-
Isaacson W. Steve Jobs. New York, NY: Simon & Schuster; 2011.
-
(2011)
Steve Jobs
-
-
Isaacson, W.1
-
6
-
-
77649234756
-
How to improve R&D productivity: The pharmaceutical industry's grand challenge
-
Paul SM, Mytelka DS, Dunwiddie CT, Persinger CC, Munos BH, Lindborg SR, Schacht AL. How to improve R&D productivity: the pharmaceutical industry's grand challenge. Nat Rev Drug Discov 2010;9:203-214.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 203-214
-
-
Paul, S.M.1
Mytelka, D.S.2
Dunwiddie, C.T.3
Persinger, C.C.4
Munos, B.H.5
Lindborg, S.R.6
Schacht, A.L.7
-
7
-
-
84878046027
-
-
Feb [accessed 2012 Jul 26]
-
- 2011 Merck Form 10-K. Merck & Co, Inc. 2012 Feb [accessed 2012 Jul 26]. Available from: http://www.merck.com/investors/financials/annual-reports/ home.html
-
(2012)
2011 Merck Form 10-K
-
-
-
8
-
-
84934766018
-
-
Apple Inc. Oct [accessed 2012 Jul 26]
-
Apple Inc. Form 10-K. Apple Inc. 2011 Oct [accessed 2012 Jul 26]. Available from: http://files.shareholder.com/downloads/AAPL/ 1990832756x0xS1193125-11-282113/320193/filing.pdf
-
(2011)
Form 10-K
-
-
-
9
-
-
73949089207
-
Funding of US biomedical research, 2003-2008
-
Dorsey ER, de Roulet J, Thompson JP, Reminick JI, Thai A, White-Stellato Z, Beck CA, George BP, Moses H III. Funding of US Biomedical Research, 2003-2008. JAMA 2010;303:137-143.
-
(2010)
JAMA
, vol.303
, pp. 137-143
-
-
Dorsey, E.R.1
De Roulet, J.2
Thompson, J.P.3
Reminick, J.I.4
Thai, A.5
White-Stellato, Z.6
Beck, C.A.7
George, B.P.8
Moses III, H.9
-
11
-
-
84878095974
-
-
Research!America. America Speaks, Poll Data Summary, Volume 5; 2004. Available from: http://www.researchamerica.org/uploads/AmericaSpeaksV5.pdf
-
(2004)
America Speaks, Poll Data Summary
, vol.5
-
-
-
12
-
-
84856197539
-
Again, and again, and again: Data replication and reproducibility
-
Jasny BR, Chin G, Chong L, Vignieri S. Again, and again, and again: Data replication and reproducibility. Science 2011;334:1225.
-
(2011)
Science
, vol.334
, pp. 1225
-
-
Jasny, B.R.1
Chin, G.2
Chong, L.3
Vignieri, S.4
-
13
-
-
84858376519
-
Scientists' elusive goal: Reproducing study results
-
Dec [accessed 2012 Aug 5]
-
Naik G. Scientists' Elusive Goal: Reproducing Study Results. Wall Street Journal 2011 Dec [accessed 2012 Aug 5]. Available from: http://online.wsj.com/ article/SB10001424052970203764804577059841672541590.html.
-
(2011)
Wall Street Journal
-
-
Naik, G.1
-
14
-
-
80055088241
-
Believe it or not: How much can we rely on published data on potential drug targets?
-
Prinz F, Schlange T, Asadullah K. Believe it or not: how much can we rely on published data on potential drug targets? Nat Rev Drug Discov 2011;10:712.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 712
-
-
Prinz, F.1
Schlange, T.2
Asadullah, K.3
-
15
-
-
84859169880
-
Drug development: Raise standards for preclinical cancer research
-
Begley CG, Ellis LM. Drug development: raise standards for preclinical cancer research. Nature 2012;483:531-533.
-
(2012)
Nature
, vol.483
, pp. 531-533
-
-
Begley, C.G.1
Ellis, L.M.2
-
16
-
-
84930828013
-
-
Sep [accessed 2012 Jul 27]
-
Reliability of 'new drug target' claims called into question. Nature.com 2011 Sep [accessed 2012 Jul 27]. Available from: http://blogs.nature.com/news/ 2011/09/reliability-of-new-drug-target.html.
-
(2011)
Reliability of 'New Drug Target' Claims Called into Question
-
-
-
19
-
-
84857425108
-
Collaborative science and the American Thoracic Society: Cooperation in harmony with conflict of interest
-
Reiss TF, Moss J, Osborne M, Curtis JR, Hill NS. Collaborative science and the American Thoracic Society: cooperation in harmony with conflict of interest. Am J Respir Crit Care Med 2012;185: 347-349.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 347-349
-
-
Reiss, T.F.1
Moss, J.2
Osborne, M.3
Curtis, J.R.4
Hill, N.S.5
-
20
-
-
84943211644
-
The care of the patient
-
Peabody FW. The care of the patient. JAMA 1927;88:877-882.
-
(1927)
JAMA
, vol.88
, pp. 877-882
-
-
Peabody, F.W.1
-
21
-
-
84875993131
-
-
Pharmaceutical Research and Manufacturers of America. [accessed 2012 Jul 26]
-
Pharmaceutical Research and Manufacturers of America. Drug discovery and development: understanding the R&D process [accessed 2012 Jul 26]. Available from: http://www.Inovation.org
-
Drug Discovery and Development: Understanding the R&D Process
-
-
-
22
-
-
79751531393
-
Heart disease and stroke statistics: 2011 update
-
American Heart Association Statistics Committee and Stroke Statistics Subcommittee
-
Roger VL, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM, Carnethon MR, Dai S, de Simone G, Ford ES, et al.; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics: 2011 update. Circulation 2011;123: e8-e209.
-
(2011)
Circulation
, vol.123
-
-
Roger, V.L.1
Go, A.S.2
Lloyd-Jones, D.M.3
Adams, R.J.4
Berry, J.D.5
Brown, T.M.6
Carnethon, M.R.7
Dai, S.8
De Simone, G.9
Ford, E.S.10
-
23
-
-
84878101046
-
-
Department of Health and Human Services, Centers for Disease Control and Prevention. [accessed 2012 Jul 26]
-
Department of Health and Human Services, Centers for Disease Control and Prevention. HIV mortality (through 2008) [accessed 2012 Jul 26]. Available from: http://www.cdc.gov/hiv/topics/surveillance/resources/slides/mortality/index. html
-
HIV Mortality (Through 2008)
-
-
-
25
-
-
73449101512
-
Lessons from 60 years of pharmaceutical innovation
-
Munos B. Lessons from 60 years of pharmaceutical innovation. Nature Reviews: Drug Discovery 2008;8:959-968.
-
(2008)
Nature Reviews: Drug Discovery
, vol.8
, pp. 959-968
-
-
Munos, B.1
|