Side effects of antibiotics on the intestinal microflora by PCR-DGGE

Pakistan Journal of Pharmaceutical Sciences

Volumn 26, Issue 2, 2013, Pages 339-343

  Li, Xinli ^a   Wu, Dachang ^a   Zhang, Cuili ^a   Xin, Yi ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Antibiotics; Intestinal microflora; PCR DGGE; Side effects

Indexed keywords

CEFRADINE; LEVOFLOXACIN; RNA 16S; ROXITHROMYCIN;

ARTICLE; CONTROLLED STUDY; DENATURING GRADIENT GEL ELECTROPHORESIS; FEMALE; INTESTINE FLORA; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SIDE EFFECT;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; BETA-LACTAMS; DENATURING GRADIENT GEL ELECTROPHORESIS; DNA, BACTERIAL; FEMALE; FLUOROQUINOLONES; INTESTINES; MACROLIDES; MICE; MICE, INBRED BALB C; POLYMERASE CHAIN REACTION; RIBOTYPING; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA; TIME FACTORS;

EID: 84878044951     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Bäckhed F, Ding H, Wang T, Hooper LV, Koh GY, Nagy A, Semenkovich CF and Gordon JI (2004). The gut microbiota as an environmental factor that regulates fat storage. P.N.A.S., 101: 15718-15723.
2. Critchley IA, Jones ME, Heinze PD, Hubbard D, Engler HD, Evangelista AT, Thornsberry C, Karlowsky JA and Sahm DF (2002). In vitro activity of levofloxacin against contemporary clinical isolates of Legionella pneumophila, Mycoplasma pneumoniae and Chlamydia pneumoniae from North America and Europe. Clin. Microbiol. Infect., 8: 214-221.
3. Dancer SJ (2004). How antibiotics can make us sick: the less obvious adverse effects of antimicrobial chemotherapy. Lancet Infect. Dis., 4: 611-619.
4. Douglas CW, Heath J, Hampton KK and Preston FE (1993). Identity of viridans streptococci isolated from cases of infective endocarditis. J. Med. Microbiol., 39: 179-182.
5. Du HL, Jiao NZ, Hu YH and Zeng YH (2006). Real-time PCR for quantification of aerobic anoxygenic phototrophic bacteria based on pufM gene in marine environment. J. Exp. Mar. Biol. Ecol., 329: 113-121.
6. Edenborn SL and Sexstone AJ (2007). DGGE Fingerprinting of culturable soil bacterial communities complements culture-independent analyses. Soil Biol. Biochem., 39: 1570-1579.
7. Fischer SG and Lerman LS (1979). Length-independent separation of DNA restriction fragments in two dimensional gel electrophoresis. Cell, 16: 191-200.
8. Flynn CM, Johnson DM and Jones RN (1996). In vitro efficacy of levofloxacin alone or in combination tested against multi-resistant Pseudomonas aeruginosa strains. J. Chemother., 8: 411-415.
9. Freedman LR (1987). The pathogenesis of infective endocarditis. J. Antimicrob. Chemother., 20: 1-6.
10. Gisbert JP, Bermejo F, Fernández MC, Aisa AP, Bermejo MF, Tomas A, Barrio J, Bory F, Almela P, Pobre PS, Cosme A, Ortiz V, Niño P, Khorrami S, Benito LM, Carneros JA, Lamas E, Modolell I, Franco A, Ortuño J, Rodrigo L, Durán FG, O'Callaghan E, Ponce J, Valer MP and Calvet X (2008). Second-line rescue therapy with levofloxacin after H. pylori treatment failure: a spanish multicenter study of 300 patients. Am. J. Gastroenterol., 103: 71-76.
11. Holt SC, Kesavalu L, Walker S and Gemco CA (1999). Virulence factors of Porphyromonas gingivalis. Periodontol. 2000, 20: 168-238.
12. Hooper LV, Wong MH, Thelin A, Hansson L, Falk PG and Gordon JI (2001). Molecular analysis of commensal host-microbial relationships in the intestine. Science, 291: 881-885.
13. Hu Q, Qi HY, Zeng JH and Zhang HX (2007). Bacterial diversity in soils around a lead and zinc mine. J. Environ. Sci., 19: 74-79.
14. Jones ME, Visser MR, Klootwijk M, Heisig P, Verhoef J and Schmitz FJ (1999). Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-resistant and-susceptible Staphylococcus aureus strains. Antimicrob. Agents. Chemother., 43: 421-423.
15. Jones RN, Rubino CM, Bhavnani SM and Ambrose PG (2003). Worldwide antimicrobial susceptibility patterns and pharmacodynamic comparisons of gatifloxacin and levofloxacin against Streptococcus pneumoniae: report from the Antimicrobial Resistance Rate Epidemiology Study Team. Antimicrob. Agents. Chemother., 47: 292-296.
16. Karlowsky JA, Thornsberry C, Critchley IA, Jones ME, Evangelista AT, Noel GJ and Sahm DF (2003). Susceptibilities to levofloxacin in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis clinical isolates from children: results from 2000-2001 and 2001-2002 TRUST Studies in the United States. Antimicrob. Agents. Chemother., 47: 1790-1797.
17. Kim HS, Chio EC and Kim BK (1988). Studies on Development of Resistant Strains to Antibiotics and Antituberculosis Agents(II) Isolation of Rifampicin Resistant Mutants from Clostridium butyricum. Arch. Pharm. Res., 11: 218-224.
18. Kong Q, He GQ, Jia JL, Zhu QL and Ruan H (2011). Oral Administration of Clostridium butyricum for Modulating Gastrointestinal Microflora in Mice. Curr. Microbiol., 62: 512-517.
19. Ledder RG, Gilbert P, Huws SA, Aarons L, Ashley MP, Hull PS and Mcbain AJ (2007). Molecular Analysis of the Subgingival Microbiota in Health and Disease. Appl. Environ. Microbiol., 73: 516-523.
20. Lesley H and Anne LM (2009). What do we mean when we refer to Bacteroidetes populations in the human gastrointestinal microbiota? FEMS. Microbiol. Lett., 299: 175-183.
21. Ley RE, Backhed F, Turnbaugh P, Lozupone CA, Knight RD and Gordon JI (2005). Obesity alters gut microbial ecology. Proc. Natl. Acad. Sci., 102: 11070-11075.
22. Li YQ, Hang XY, Yao LH, Shi RH and Zhang GX (2010). Advantages of Moxifloxacin and Levofloxacin-based triple therapy for second-line treatments of persistent Helicobacter pylori infection: a meta analysis. Wien. Klin. Wochenschr., 122: 413-422.
23. Murray RG, Brenner DJ and Bryant M P (1984). Bergey's manual of systematic bacteriology. Williams & Wilkins., 2: 1160-1161.
24. Muyzer G, Dewaal EC and Uitterlinden AG (1993). Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. Appl. Environ. Microbiol., 59: 695-700.
25. Reisner DP (1996). Uses of macrolide antibiotics in obstetrics and gynecology. Infect. Dis. Update. 3: 122-127
26. Sears CL (2005). A dynamic partnership: Celebratingour gut flora. Anaerobe, 11: 247-251.
27. Sprandel KA and Rocivold KA (2003). Safety and tolerability of fluoroquinolones. Clin. Cornerstone., 5: 29-36.
28. Stappenbeck TS, Hooper LV and Gordon JI (2002). Developmental regulation of intestinal angiogenesis by indigenous microbes via paneth cells. P.N.A.S., 99: 15451-15455.
29. Swenson FJ and Rubin SJ (1982). Clinical significance of viridans streptococci isolated from blood cultures. J. Clin. Microbiol., 15: 725-727.
30. Whitehead TR (1997). Development of a bifunctional xylosidase/ arabinosidase gene as a reporter gene for the Gram-Negative anaerobes Bacteroides and Porphyromonas, and Escherichia coli. Curr. Microbiol., 35: 282-286.