Chronic Non-Infectious Pulmonary Complications in Haematopoietic Stem Cell Transplantation

Pulmonary Infection in the Immunocompromised Patient: Strategies for Management

Volumn , Issue , 2009, Pages 257-281

  Afessa, Bekele ^a   Peters, Steve G ^a  

^a Mayo Clinic   (United States)

Author keywords

Bronchiolitis obliterans (BO); Bronchiolitis obliterans organizing pneumonia (BOOP); Chronic non infectious pulmonary complications in HSCT; Delayed pulmonary toxicity syndrome (DPTS); Diagnostic approach to haematopoietic stem cell transplant recipient; GVHD and histologic pulmonary manifestations; Idiopathic pneumonia syndrome (IPS); Non infectious pulmonary complications in haematopoietic stem cell transplant recipients; Peri engraftment respiratory distress syndrome (PERDS)

Indexed keywords

EID: 84878030266     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470714171.ch9     Document Type: Chapter

References (120)

1. Abratt, R.P., Morgan, G.W., Silvestri, G. and Willcox, P. (2004) Pulmonary complications of radiation therapy. Clinics in Chest Medicine, 25, 167-177.
2. Afessa, B., Litzow, M.R. and Tefferi, A. (2001) Bronchiolitis obliterans and other late onset non-infectious pulmonary complications in hematopoietic stem cell transplantation. Bone Marrow Transplantation, 28, 425-434.
3. Afessa, B. and Peters, S.G. (2005) Chronic lung disease after hematopoietic stem cell transplantation. Clinics in Chest Medicine, 26, 571-586, vi.
4. Afessa, B. and Peters, S.G. (2006) Major complications following hematopoietic stem cell transplantation. Seminars in Respiratory and Critical Care Medicine, 27, 297-309.
5. Afessa, B., Tefferi, A., Litzow, M.R. et al. (2002a) Diffuse alveolar hemorrhage in hematopoietic stem cell transplant recipients. American Journal of Respiratory and Critical Care Medicine, 166, 641-645.
6. Afessa, B., Tefferi, A., Litzow, M.R. and Peters, S.G. (2002b) Outcome of diffuse alveolar hemorrhage in hematopoietic stem cell transplant recipients. American Journal of Respiratory and Critical Care Medicine, 166, 1364-1368.
7. Agusti, C., Ramirez, J., Picado, C. et al. (1995) Diffuse alveolar hemorrhage in allogeneic bone marrow transplantation. A postmortem study. American Journal of Respiratory and Critical Care Medicine, 151, 1006-1010.
8. Akasheh, M., Eastwood, D. and Vesole, D.H. (2003) Engraftment syndrome after autologous hematopoietic stem cell transplant supported by granulocyte-colony-stimulating factor (G-CSF) versus granulocyte-macrophage colony-stimulating factor (GM-CSF). Bone Marrow Transplantation, 31, 113-116.
9. Alasaly, K., Muller, N., Ostrow, D.N. et al. (1995) Cryptogenic organizing pneumonia. A report of 25 cases and a review of the literature. Medicine (Baltimore), 74, 201-211.
10. Au, W.Y., Lie, A.K., Kwong, Y.L. et al. (2002) Post-transplantation lymphoproliferative disease in Chinese: the Queen Mary Hospital experience in Hong Kong. Leukemia & Lymphoma, 43, 1403-1407.
11. Bergeron, A., Belle, A., Chevret, S. et al. (2007) Combined inhaled steroids and bronchodilatators in obstructive airway disease after allogeneic stem cell transplantation. Bone Marrow Transplantation, 39, 547-553.
12. Bhagat, R., Rizzieri, D.A., Vredenburgh, J.J. et al. (2004) Pulmonary sarcoidosis following stem cell transplantation: is it more than a chance occurrence? Chest, 126, 642-644.
13. Bisaccia, E., Palangio, M., Gonzalez, J. et al. (2006) Treatment of extensive chronic graft-versus-host disease with extracorporeal photochemotherapy. Journal of Clinical Apheresis, 21, 181-187.
14. Bojko, T., Notterman, D.A., Greenwald, B.M. et al. (1995) Acute hypoxemic respiratory failure in children following bone marrow transplantation: an outcome and pathologic study. Critical Care Medicine, 23, 755-759.
15. Bruckmann, C., Lindner, W., Roos, R. et al. (1991) Severe pulmonary vascular occlusive disease following bone marrow transplantation in Omenn syndrome. European Journal of Pediatrics, 150, 242-245.
16. Brunet, S., Muniz-Diaz, E. and Baiget, M. (1994) Chronic eosinophilic pneumonia in a patient treated with allogeneic bone marrow transplantation. Medicina Clinica (Bare), 103, 677.
17. Cahill, R.A., Spitzer, T.R. and Mazumder, A. (1996) Marrow engraftment and clinical manifestations of capillary leak syndrome. Bone Marrow Transplantation, 18, 177-184.
18. Capizzi, S.A., Kumar, S., Huneke, N.E. et al. (2001) Peri-engraftment respiratory distress syndrome during autologous hematopoietic stem cell transplantation. Bone Marrow Transplantation, 27, 1299-1303.
19. Carlens, S., Ringden, O., Remberger, M. et al. (1998) Riskfactors for chronic graft-versus-host disease after bone marrow transplantation: a retrospective single centre analysis. Bone Marrow Transplantation, 22, 755-761.
20. Chen, C.S., Boeckh, M., Seidel, K. et al. (2003) Incidence, riskfactors, and mortality from pneumonia developing late after hematopoietic stem cell transplantation. Bone Marrow Transplantation, 32, 515-522.
21. Chien, J.W., Martin, PJ., Flowers, M.E. et al. (2004) Implications of early airflow decline after myeloablative allogeneic stem cell transplantation. Bone Marrow Transplantation, 33, 759-764.
22. Chien, J.W., Martin, PJ., Gooley, T.A. et al. (2003) Airflow obstruction after myeloablative allogeneic hematopoietic stem cell transplantation. American Journal of Respiratory and Critical Care Medicine, 168, 208-214.
23. Clark, J.G., Crawford, S.W., Madtes, D.K. and Sullivan, K.M. (1989) Obstructive lung disease after allogeneic marrow transplantation. Clinical presentation and course. Annals of Internal Medicine, 111, 368-376.
24. Clark, J.G., Hansen, J.A., Hertz, M.I. et al. (1993) NHLBI workshop summary. Idiopathic pneumonia syndrome after bone marrow transplantation. The American Review of Respiratory Disease, 147, 1601-1606.
25. Cooke, K.R. and Yanik, G. (2004) Acute lung injury after allogeneic stem cell transplantation: is the lung a target of acute graft-versus-host disease? Bone Marrow Transplantation, 34, 753-765.
26. Copelan, E.A. (2006) Hematopoietic stem-cell transplantation. The New England Journal of Medicine, 354, 1813-1826.
27. Cordonnier, C., Fleury-Feith, J., Escudier, E. et al. (1994) Secondary alveolar proteinosis is a reversible cause of respiratory failure in leukemic patients. American Journal of Respiratory and Critical Care Medicine, 149, 788-794.
28. Crawford, S.W. and Clark, J.G. (1993) Bronchiolitis associated with bone marrow transplantation. Clinics in Chest Medicine, 14, 741-749.
29. Crawford, S.W. and Hackman, R.C. (1993) Clinical course of idiopathic pneumonia after bone marrow transplantation. The American Review of Respiratory Disease, 147, 1393-1400.
30. Crawford, S.W., Longton, G. and Storb, R. (1993) Acute graft-versus-host disease and the risks for idiopathic pneumonia after marrow transplantation for severe aplastic anemia. Bone Marrow Transplantation, 12, 225-231.
31. Dickout, W.J., Chan, C.K., Hyland, R.H. et al. (1987) Prevention of acute pulmonary edema after bone marrow transplantation. Chest, 92, 303-309.
32. Ditschkowski, M., Elmaagacli, A.H., Trenschel, R. et al. (2007) T-cell depletion prevents from bronchiolitis obliterans and bronchiolitis obliterans with organizing pneumonia after allogeneic hematopoietic stem cell transplantation with related donors. Haematologica, 92, 558-561.
33. Dudek, A.Z., Mahaseth, H., DeFor, T.E. and Weisdorf, D.J. (2003) Bronchiolitis obliterans in chronic graft-versus-host disease: analysis of risk factors and treatment outcomes. Biology of Blood and Marrow Transplantation, 9, 657-666.
34. Estenne, M., Maurer, J.R., Boehler, A. et al. (2002) Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria. The Journal of Heart and Lung Transplantation, 21, 297-310.
35. Favaloro, R., Bertolotti, A., Gomez, C. et al. (2004) Lung transplant at the Favaloro Foundation: a 13-year experience. Transplantation Proceedings, 36, 1689-1691.
36. Fullmer, J.J., Fan, L.L., Dishop, M.K. et al. (2005) Successful treatment of bronchiolitis obliterans in a bone marrow transplant patient with tumor necrosis factor-alpha blockade. Pediatrics, 116, 767-770.
37. Gooneratne, L., Lim, Z.Y., Vivier, A. et al. (2007) Sarcoidosis as an unusual cause of hepatic dysfunction following reduced intensity conditioned allogeneic stem cell transplantation. Bone Marrow Transplantation, 39, 511-512.
38. Gosselin, M.V. and Adams, R.H. (2002) Pulmonary complications in bone marrow transplantation. Journal of Thoracic Imaging, 17, 132-144.
39. Griese, M., Rampf, U., Hofmann, D. et al. (2000) Pulmonary complications after bone marrow transplantation in children: twenty-four years of experience in a single pediatric center. Pediatric Pulmonology, 30, 393-401.
40. Gross, T.G., Hoge, FJ., Jackson, J.D. et al. (1994) Fatal eosinophilic disease following autologous bone marrow transplantation. Bone Marrow Transplantation, 14, 333-337.
41. Gulbahce, H.E., Manivel, J.C. and Jessurun, J. (2000) Pulmonary cytolytic thrombi: a previously unrecognized complication of bone marrow transplantation. The American Journal of Surgical Pathology, 24, 1147-1152.
42. Gulbahce, H.E., Pambuccian, S.E., Jessurun, J. et al. (2004) Pulmonary nodular lesions in bone marrow transplant recipients: impact of histologic diagnosis on patient management and prognosis. American Journal of Clinical Pathology, 121, 205-210.
43. Gupta, S., Jain, A., Warneke, C.L. et al. (2007) Outcome of alveolar hemorrhage in hematopoietic stem cell transplant recipients. Bone Marrow Transplantation, 40, 71-78.
44. Hauber, H.P., Mikkila, A., Erich, J.M. et al. (2002) TNFalpha, interleukin-10 and interleukin-18 expression in cells of the bronchoalveolar lavage in patients with pulmonary complications following bone marrow or peripheral stem cell transplantation: a preliminary study. Bone Marrow Transplantation, 30, 485-490.
45. Hayes-Jordan, A., Benaim, E., Richardson, S. et al. (2002) Open lung biopsy in pediatric bone marrow transplant patients. Journal of Pediatric Surgery, 37, 446-452.
46. Heath, J.A., Kurland, G., Spray, T.L. et al. (2001) Lung transplantation after allogeneic marrow transplantation in pediatric patients: the Memorial Sloan-Kettering experience. Transplantation, 72, 1986-1990.
47. Hicks, K., Peng, D. and Gajewski, J.L. (2002) Treatment of diffuse alveolar hemorrhage after allogeneic bone marrow transplant with recombinant factor VIIa. Bone Marrow Transplantation, 30, 975-978.
48. Hildebrandt, G.C., Olkiewicz, K.M., Corrion, L.A. et al. (2004) Donor-derived TNF-alpha regulates pulmonary chemokine expression and the development of idiopathic pneumonia syndrome after allogeneic bone marrow transplantation. Blood, 104, 586-593.
49. Huaringa, A.J., Leyva, F.J., Giralt, S.A. et al. (2000) Outcome of bone marrow transplantation patients requiring mechanical ventilation [see comments]. Critical Care Medicine, 28, 1014-1017.
50. Huisman, C., van der Straaten, H.M., Canninga-van Dijk, M.R. et al. (2006) Pulmonary complications after T-cell-depleted allogeneic stem cell transplantation: low incidence and strong association with acute graft-versus-host disease. Bone Marrow Transplantation, 38, 561-566.
51. Ishii, T., Manabe, A., Ebihara, Y. et al. (2000) Improvement in bronchiolitis obliterans organizing pneumonia in a child after allogeneic bone marrow transplantation by a combination of oral prednisolone and low dose erythromycin [In Process Citation]. Bone Marrow Transplantation, 26, 907-910.
52. Jung, J.I., Jung, W.S., Hahn, S.T. et al. (2004) Bronchiolitis obliterans after allogenic bone marrow transplantation: HRCT findings. Korean Journal of Radiology, 5, 107-113.
53. Kanamori, H., Fujisawa, S., Tsuburai, T. et al. (2002) Increased exhaled nitric oxide in bronchiolitis obliterans organizing pneumonia after allogeneic bone marrow transplantation. Transplantation, 74, 1356-1358.
54. Kang, S.K., Kirkpatrick, J.P. and Halperin, E.C. (2003) Low-dose radiation for posttransplant lymphoproliferative disorder. American Journal of Clinical Oncology, 26, 210-214.
55. Kantrow, S.P., Hackman, R.C., Boeckh, M. et al. (1997) Idiopathic pneumonia syndrome: changing spectrum of lung injury after marrow transplantation. Transplantation, 63, 1079-1086.
56. Keates-Baleeiro, J., Moore, P., Koyama, T. et al. (2006) Incidence and outcome of idiopathic pneumonia syndrome in pediatric stem cell transplant recipients. Bone Marrow Transplantation, 38, 285-289.
57. Khalid, M., Al Saghir, A., Saleemi, S. et al. (2005) Azithromycin in bronchiolitis obliterans complicating bone marrow transplantation: a preliminary study. The European Respiratory Journal, 25, 490-493.
58. Knop, S., Bux, J., Kroeber, S.M. et al. (2004) Fatal immune-mediated pancytopenia and a TRALI-like syndrome associated with high titers of recipient-type antibodies against donor-derived peripheral blood cells after allogeneic bone marrow transplantation following dose reduced conditioning. Haematologica, 89, ECR12.
59. Krowka, M.J., Rosenow, E.C., III, Hoagland, H.C. (1985) Pulmonary complications of bone marrow transplantation. Chest, 87, 237-246.
60. Kunitomi, A., Arima, N. and Ishikawa, T. (2007) Epstein-Barr virus-associated post-transplant lymphoproliferative disorders presented as interstitial pneumonia; successful recovery with ritux-imab. Haematologica, 92, 92e049.
61. Lewis, I.D., DeFor, T. and Weisdorf, D.J. (2000) Increasing incidence of diffuse alveolar hemorrhage following allogeneic bone marrow transplantation: cryptic etiology and uncertain therapy. Bone Marrow Transplantation, 26, 539-543.
62. Limper, A.H. (2004) Chemotherapy-induced lung disease. Clinics in Chest Medicine, 25, 53-64.
63. Maiolino, A., Biasoli, I., Lima, J. et al. (2003) Engraftment syndrome following autologous hematopoietic stem cell transplantation: definition of diagnostic criteria. Bone Marrow Transplantation, 31, 393-397.
64. Mandanas, R.A., Saez, R.A., Selby, G.B. and Confer, D.L. (1996) Cytomegalovirus surveillance and prevention in allogeneic bone marrow transplantation: examination of a preemptive plan of ganciclovir therapy. American Journal of Hematology, 51, 104-111.
65. Marras, T.K., Chan, C.K., Lipton, J.H. et al. (2004) Long-term pulmonary function abnormalities and survival after allogeneic marrow transplantation. Bone Marrow Transplantation, 33, 509-517.
66. Marras, T.K., Szalai, J.P., Chan, C.K. et al. (2002) Pulmonary function abnormalities after allogeneic marrow transplantation: a systematic review and assessment of an existing predictive instrument. Bone Marrow Transplantation, 30, 599-607.
67. Mathew, P., Bozeman, P., Krance, R.A. et al. (1994) Bronchiolitis obliterans organizing pneumonia (BOOP) in children after allogeneic bone marrow transplantation. Bone Marrow Transplantation, 13, 221-223.
68. Matulis, M. and High, K.P. (2002) Immune reconstitution after hematopoietic stem-cell transplantation and its influence on respiratory infections. Seminars in Respiratory Infections, 17, 130-139.
69. McDonald, G.B., Sullivan, K.M. and Plumley, T.F. (1984) Radiographic features of esophageal involvement in chronic graft-vs.-host disease. American Journal of Roentgenology, 142, 501-506.
70. McGaughey, D.S., Nikcevich, D.A., Long, G.D. et al. (2001) Inhaled steroids as prophylaxis for delayed pulmonary toxicity syndrome in breast cancer patients undergoing high-dose chemotherapy and autologous stem cell transplantation. Biology of Blood and Marrow Transplantation, 7, 274-278.
71. Metcalf, J.P., Rennard, S.I., Reed, E.C. et al. (1994) Corticosteroids as adjunctive therapy for diffuse alveolar hemorrhage associated with bone marrow transplantation. University of Nebraska Medical Center Bone Marrow Transplant Group. The American Journal of Medicine, 96, 327-334.
72. Monforte-Munoz, H., Kapoor, N. and Saavedra, J.A. (2003) Epstein-Barr virus-associated leiomyomatosis and posttransplant lymphoproliferative disorder in a child with severe combined immunodeficiency: case report and review of the literature. Pediatric and Developmental Pathology, 6, 449-457.
73. Morales, I.J., Anderson, P.M., Tazelaar, H.D. and Wylam, M.E. (2003) Pulmonary cytolytic thrombi: unusual complication of hematopoietic stem cell transplantation. Journal of Pediatric Hematology/ Oncology, 25, 89-92.
74. Mossad, S., Kalaycio, M., Sobecks, R. et al. (2005) Steroids prevent engraftment syndrome after autologous hematopoietic stem cell transplantation without increasing the risk of infection. Bone Marrow Transplantation, 35, 375-381.
75. Myers, J.L. and Colby, T.V. (1993) Pathologic manifestations of bronchiolitis, constrictive bronchiolitis, cryptogenic organizing pneumonia, and diffuse panbronchiolitis. Clinics in Chest Medicine, 14, 611-622.
76. Noji, H., Shichishima, T., Ogawa, K. et al. (2004) Transfusion-related acute lung injury following allogeneic bone marrow transplantation in a patient with acute lymphoblastic leukemia. Internal Medicine (Tokyo, Japan), 43, 1068-1072.
77. Or, R., Gesundheit, B., Resnick, I. et al. (2007) Sparing effect by montelukast treatment for chronic graft versus host disease: a pilot study. Transplantation, 83, 577-581.
78. Padilla, M.L., Schilero, G.J. and Teirstein, A.S. (2002) Donor-acquired sarcoidosis. Sarcoidosis, Vasculitis, and Diffuse Lung Diseases, 19, 18-24.
79. Pastores, S.M., Papadopoulos, E., Voigt, L. and Halpern, N.A. (2003) Diffuse alveolar hemorrhage after allogeneic hematopoietic stem-cell transplantation: treatment with recombinant factor VIIa. Chest, 124, 2400-2403.
80. Paz, H.L., Crilley, P., Patchefsky, A. et al. (1992) Bronchiolitis obliterans after autologous bone marrow transplantation. Chest, 101, 775-778.
81. Pechet, T.V., de le, M.M., Mendeloff, E.N. et al. (2003) Lung transplantation in children following treatment for malignancy. The Journal of Heart and Lung Transplantation, 22, 154-160.
82. Pedrazzoli, P., Ferrante, P., Kulekci, A. et al. (2003) Autologous hematopoietic stem cell transplantation for breast cancer in Europe: critical evaluation of data from the European Group for Blood and Marrow Transplantation (EBMT) Registry 1990-1999. Bone Marrow Transplantation, 32, 489-494.
83. Peters, A., Manivel, J.C., Dolan, M. et al. (2005) Pulmonary cytolytic thrombi after allogeneic hematopoietic cell transplantation: a further histologic description. Biology ofBlood and Marrow Transplantation, 11, 484-485.
84. Peters, S.G. and Afessa, B. (2005) Acute lung injury after hematopoietic stem cell transplantation. Clinics in Chest Medicine, 26, 561-569 vi.
85. Presneill, J.J., Nakata, K., Inoue, Y. and Seymour, J.F. (2004) Pulmonary alveolar proteinosis. Clinics in Chest Medicine, 25, 593-613, viii.
86. Rabitsch, W., Deviatko, E., Keil, F. et al. (2001) Successful lung transplantation for bronchiolitis obliterans after allogeneic marrow transplantation. Transplantation, 71, 1341-1343.
87. Redel-Montero, J., Santos-Luna, F., Lama-Martinez, R. et al. (2006) A lung transplant in a woman with bronchiolitis obliterans following an allogenic bone marrow transplant. Archivos de Bronco-neumologia, 42, 151-153.
88. Richard, C., Calavia, J., Loyola, I. et al. (1994) Chronic eosinophilic pneumonia in a patient treated with allogenic bone marrow transplantation. Medicina Clinica (Barc), 102, 462-464.
89. Robbins, R.A., Linder, J., Stahl, M.G. et al. (1989) Diffuse alveolar hemorrhage in autologous bone marrow transplant recipients [see comments]. The American Journal of Medicine, 87, 511-518.
90. Roychowdhury, M., Pambuccian, S.E., Aslan, D.L. et al. (2005) Pulmonary complications after bone marrow transplantation: an autopsy study from a large transplantation center. Archives of Pathology & Laboratory Medicine, 129, 366-371.
91. Sano, Y., Date, H., Nagahiro, I. et al. (2005) Living-donor lobar lung transplantation for bronchiolitis obliterans after bone marrow transplantation. The Annals of Thoracic Surgery, 79, 1051-1052.
92. Schots, R., Kaufman, L., Van Riet, I. et al. (2003) Proinflammatory cytokines and their role in the development of major transplant-related complications in the early phase after allogeneic bone marrow transplantation. Leukemia, 17, 1150-1156.
93. Shankar, S., Choi, J.K., Dermody, T.S. et al. (2004) Pulmonary hypertension complicating bone marrow transplantation for idiopathic myelofibrosis. Journal of Pediatric Hematology/Oncology, 26, 393-397.
94. Sharma, S., Nadrous, H.F., Peters, S.G. et al. (2005) Pulmonary complications in adult blood and marrow transplant recipients: autopsy findings. Chest, 128, 1385-1392.
95. Shoji, N., Ohyashiki, J.H., Suzuki, A. et al. (2003) Multiple pulmonary nodules caused by B-cell posttransplant lymphoproliferative disorder after bone marrow transplantation: monitoring Epstein-Barr virus viral load. Japanese Journal of Clinical Oncology, 33, 408-412.
96. Sisson, J.H., Thompson, A.B., Anderson, J.R. et al. (1992) Airway inflammation predicts diffuse alveolar hemorrhage during bone marrow transplantation in patients with Hodgkin disease. The American Review of Respiratory Disease, 146, 439-443.
97. Sloane, J.P., Depledge, M.H., Powles, R.L. et al. (1983) Histopathology of the lung after bone marrow transplantation. Journal of Clinical Pathology, 36, 546-554.
98. St.John, R.C., Gadek, J.E., Tutschka, PJ. et al. (1990) Analysis of airflow obstruction by bronch-oalveolar lavage following bone marrow transplantation. Implications for pathogenesis and treatment. Chest, 98, 600-607.
99. Suratt, B.T., Lynch, D.A., Cool, C.D. et al. (2003) Interferon-gamma for delayed pulmonary toxicity syndrome resistant to steroids. Bone Marrow Transplantation, 31, 939-941.
100. Thirman, M.J., Devine, S.M., O'Toole, K. et al. (1992) Bronchiolitis obliterans organizing pneumonia as a complication of allogeneic bone marrow transplantation [see comments]. Bone Marrow Transplantation, 10, 307-311.
101. Thompson, A.M., Couch, M., Zahurak, M.L. et al. (2002) Risk factors for post-stem cell transplant sinusitis. Bone Marrow Transplantation, 29, 257-261.
102. Todd, N.W., Peters, W.P., Ost, A.H. et al. (1993) Pulmonary drug toxicity in patients with primary breast cancer treated with high-dose combination chemotherapy and autologous bone marrow transplantation. The American Review of Respiratory Disease, 147, 1264-1270.
103. Tolar, J., Coad, J.E., Ramsay, N.K. et al. (2001) Lymphoproliferative disorder presenting as pulmonary nodules after bone marrow transplantation. Bone Marrow Transplantation, 28, 808-810.
104. Trisolini, R., Stanzani, M., Agli, L.L. et al. (2001) Delayed non-infectious lung disease in allogeneic bone marrow transplant recipients. Sarcoidosis, Vasculitis, and Diffuse Lung Diseases, 18, 75-84.
105. Uberti, J.P., Ayash, L., Ratanatharathorn, V. et al. (2005) Pilot trial on the use of etanercept and methylprednisolone as primary treatment for acute graft-versus-host disease. Biology of Blood and Marrow Transplantation, 11, 680-687.
106. Urahama, N., Tanosaki, R., Masahiro, K. et al. (2003) TRALI after the infusion of marrow cells in a patient with acute lymphoblastic leukemia. Transfusion, 43, 1553-1557.
107. Vaksmann, G., Nelken, B., Deshildre, A. and Rey, C. (2002) Pulmonary arterial occlusive disease following chemotherapy and bone marrow transplantation for leukaemia. European Journal of Pediatrics, 161, 247-249.
108. Wah, T.M., Moss, H.A., Robertson, R.J. and Barnard, D.L. (2003) Pulmonary complications following bone marrow transplantation. British Journal of Radiology, 76, 373-379.
109. Wilczynski, S.W., Erasmus, J.J., Petros, W.P. et al. (1998) Delayed pulmonary toxicity syndrome following high-dose chemotherapy and bone marrow transplantation for breast cancer. American Journal of Respiratory and Critical Care Medicine, 157, 565-573.
110. Wingard, J.R., Mellits, E.D., Jones, R.J. et al. (1989) Association of hepatic veno-occlusive disease with interstitial pneumonitis in bone marrow transplant recipients. Bone Marrow Transplantation, 4, 685-689.
111. Wingard, J.R., Mellits, E.D., Sostrin, M.B. et al. (1988a) Interstitial pneumonitis after allogeneic bone marrow transplantation. Nine-year experience at a single institution. Medicine (Baltimore), 67, 175-186.
112. Wingard, J.R., Sostrin, M.B., Vriesendorp, H.M. et al. (1988b) Interstitial pneumonitis following autologous bone marrow transplantation. Transplantation, 46, 61-65.
113. Witte, R.J., Gurney, J.W., Robbins, R.A. et al. (1991) Diffuse pulmonary alveolar hemorrhage after bone marrow transplantation: radiographic findings in 39 patients. American Journal of Roentgenology, 157, 461-464.
114. Wojno, K.J., Vogelsang, G.B., Beschorner, W.E. and Santos, G.W. (1994) Pulmonary hemorrhage as a cause of death in allogeneic bone marrow recipients with severe acute graft-versus-host disease. Transplantation, 57, 88-92.
115. Wong, R., Rondon, G., Saliba, R.M. et al. (2003) Idiopathic pneumonia syndrome after high-dose chemotherapy and autologous hematopoietic stem cell transplantation for high-risk breast cancer. Bone Marrow Transplantation, 31, 1157-1163.
116. Woodard, J.P., Gulbahce, E., Shreve, M. et al. (2000) Pulmonary cytolytic thrombi: a newly recognized complication of stem cell transplantation. Bone Marrow Transplantation, 25, 293-300.
117. Worthy, S.A., Flint, J.D. and Muller, N.L. (1997) Pulmonary complications after bone marrow transplantation: high-resolution CT and pathologic findings. Radiographics, 17, 1359-1371.
118. Yanik, G., Hellerstedt, B., Custer, J. et al. (2002) Etanercept (Enbrel) administration for idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation, 8, 395-400.
119. Yotsumoto, S., Okada, F., Yotsumoto, S. et al. (2007) Bronchiolitis obliterans organizing pneumonia after bone marrow transplantation: association with human leukocyte antigens. Journal of Computer Assisted Tomography, 31, 132-137.
120. Yousem, S.A. (1995) The histological spectrum of pulmonary graft-versus-host disease in bone marrow transplant recipients. Human Pathology, 26, 668-675.