Identification of two genes potentially associated in iron-heme homeostasis in human carotid plaque using microarray analysis

Journal of Biosciences

Volumn 38, Issue 2, 2013, Pages 311-315

  Ayari, Hanène ^a   Bricca, Giampiero ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Human carotid plaque; iron heme homeostasis; microarray

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; CD163 ANTIGEN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HEME; HEME OXYGENASE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IRON; MESSENGER RNA;

CARDIOVASCULAR DISEASE; GENE EXPRESSION; HOMEOSTASIS; HYPERTENSION; IRON; RNA; SYMPTOM;

AGED; ANALYZER; ARTICLE; CAROTID ATHEROSCLEROSIS; CAROTID ENDARTERECTOMY; CD163 GENE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; GENE INDUCTION; HEME HOMEOSTASIS; HEME OXYGENASE 1 GENE; HOMEOSTASIS; HUMAN; HUMAN TISSUE; IRON BALANCE; MALE; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; TISSUE SECTION;

AGED; AGED, 80 AND OVER; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CAROTID ARTERY DISEASES; DIABETES MELLITUS, TYPE 2; FEMALE; HEME; HEME OXYGENASE-1; HOMEOSTASIS; HUMANS; HYPERTENSION; IRON; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLAQUE, ATHEROSCLEROTIC; RECEPTORS, CELL SURFACE; RNA, MESSENGER; TRANSCRIPTIONAL ACTIVATION; TRANSCRIPTOME;

EID: 84878019601     PISSN: 02505991     EISSN: 09737138     Source Type: Journal    
DOI: 10.1007/s12038-013-9310-2     Document Type: Article

References (15)

1. Adams L, Geary R, Li J, Rossini A and Schwartz S 2006 Expression profiling identifies smooth muscle cell diversity within human intima and plaque fibrous cap: loss of RGS5 distinguishes the cap. Arterioscler. Thromb. Vasc. Biol. 26 319-325
2. Barnett HJ, Taylor DW, Eliasziw M, Fox AJ, Ferguson GG, Haynes RB, Rankin RN, Clagett GP, et al. 1998 Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis: North American Symptomatic Carotid Endarterectomy Trial Collaborators. New Engl. J. Med. 339 1415-1425
3. Dhore CR, Cleutjens JP, Lutgens E, Cleutjens KB, Geusens PP, Kitslaar PJ, Tordoir JH, Spronk HM, Vermeer C and Daemen MJ 1998 Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. Arterioscler. Thromb. Vasc. Biol. 21 56-60
4. Duckers HJ, Boehm M, True AL, Yet SF, San H, Park JL, Clinton Webb R, Lee ME, Nabel GJ and Nabel EG 2001 Heme oxygenase-1 protects against vascular constriction and proliferation. Nat. Med. 7 693-698
5. Faber BCG, Cleutjens KBJM, Niessen RLJ, Aarts PLJW, Boon W, Greenberg AS, Kitslaar PJEHM, Tordoir JHM and Daemen MJAP 2001 Identification of genes potentially involved in rupture of human atherosclerotic plaques. Circ. Res. 89 547-554
6. Golledge J, Greenhalgh RM and Davies AH 2000 The symptomatic carotid plaque. Stroke 3 774-781
7. Kappelle LJ 2002 Symptomatic carotid artery stenosis. J. Neurol. 249 254-259
8. Papaspyridonos M, Smith A, Burnand K, Taylor P, Padayachee S, Suckling K, James C, Greaves D and Patel L 2006 Novel candidate genes in unstable areas of human atherosclerotic plaques. Arterioscler. Thromb. Vasc. Biol. 26 1837-1844
9. Ijäs P, Nuotio K, Saksi J, Soinne L, Saimanen E, Karjalainen-Lindsberg ML, Salonen O, Sarna S, Tuimala J, et al. 2007 Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques. Arterioscler. Thromb. Vasc. Biol. 27 154-160
10. Randi A, Biguzzi E, Falciani F, Merlini P, Blakemore S, Bramucci E, Lucreziotti S, Lennon M, et al. 2003 Identification of differentially expressed genes in coronary atherosclerotic plaques from patients with stable or unstable angina by cDNA array analysis. J Thromb. Haemost. 1 829-835
11. Schaer DJ 2002 The macrophage hemoglobin scavenger receptor (CD163) as a genetically determined disease modifying pathway in atherosclerosis. Atherosclerosis 163 199-201
12. Siow RC, Sato H and Mann GE 1999 Heme oxygenase-carbon monoxide signalling pathway in atherosclerosis: anti-atherogenic actions of bilirubin and carbon monoxide? Cardiovasc. Res. 41 385-394
13. Stary HC, Chandler AB, Dinsmore RE, Fuster V, Glagov S, Insull WJ, Rosenfeld ME, Schwartz CJ, Wagner WD and Wissler WD 1995 A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis: A report from the Comittee on Vascular Lesions of the Council on Arteriosclerosis, AHA. Circulation 92 1355-1374
14. Takaya N, Yuan C, Chu B, Saam T, Underhill H, Cai J, Tran N, Polissar NL, et al. 2006 Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospectivenassessment with MRI-initial results. Stroke 37 818-823
15. World Physician Organization 1997 World Physician Organization declaration of Helsinki. Cardiovasc. Res. 35 2-3