Nodular regenerative hyperplasia in Common Variable Immunodeficiency

Journal of Clinical Immunology

Volumn 33, Issue 4, 2013, Pages 748-758

  Fuss, Ivan J ^a,f   Friend, Julia ^a,d   Yang, Zhiqiong ^a   He, Jian Ping ^a   Hooda, Lubna ^a,b   Boyer, James ^c   Xi, Liqiang ^d   Raffeld, Mark ^d   Kleiner, David E ^d   Heller, Theo ^e   Strober, Warren ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b SAIC FREDERICK INC   (United States)

^c YALE UNIVERSITY   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^f Laboratory of Host Defenses   (United States)

Author keywords

autoimmune; CVID; cytokine; hypertension; liver; NRH

Indexed keywords

ALKALINE PHOSPHATASE; AZATHIOPRINE; CYTOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN; MERCAPTOPURINE; PREDNISONE; SILDENAFIL; STEROID;

ADULT; ARTICLE; ASCITES; AUTOIMMUNE HEPATITIS; CAUSE OF DEATH; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; COMMON VARIABLE IMMUNEDEFICIENCY; COMMON VARIABLE IMMUNODEFICIENCY; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FIBROSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERSPLENISM; IMMUNE DEFICIENCY; LIVER BIOPSY; LIVER DISEASE; LIVER DYSFUNCTION; LIVER HYPERPLASIA; LYMPHOCYTIC INFILTRATION; MALE; NEUTROPENIA; NODULAR REGENERATIVE HYPERPLASIA; PORTAL HYPERTENSION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PULMONARY HYPERTENSION; RETROSPECTIVE STUDY; SCHOOL CHILD; T LYMPHOCYTE; THROMBOCYTOPENIA;

ADOLESCENT; ADULT; ALKALINE PHOSPHATASE; AUTOIMMUNITY; CHILD; COMMON VARIABLE IMMUNODEFICIENCY; CYTOKINES; FEMALE; FOCAL NODULAR HYPERPLASIA; FOLLOW-UP STUDIES; HUMANS; INTERFERON-GAMMA; LIVER; MALE; MIDDLE AGED; PREVALENCE; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84878014146     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-013-9873-6     Document Type: Article

References (24)

1. Oksenhendler E, Gérard L, Fieschi C, Malphettes M, Moillot G, Jaussaud R, et al. DEFI Study Group. Infections in 252 patients with common variable immunodeficiency. Clin Infect Dis. 2008;46:1547-54.
2. Agarwal S, Cunningham-Rundles C. Autoimmunity in common variable immunodeficiency. Curr Allergy Asthma Rep. 2009;9:347-52.
3. Resnick ES, Moshier EL, Godbold JH, Cunningham-Rundles C. Morbidity and mortality in common variable immune deficiency over 4 decades. Blood. 2012;119:1650-7.
4. Cunningham-Rundles C, Radigan L, Knight AK, Bauer L, Nakazawa A. TLR9 activation is defective in common variable immune deficiency. J Immunol. 2006;176:1978-87.
5. Salzer U, Grimbacher B. Common variable immunodeficiency: the power of co-stimulation. Semin Immunol. 2006;18:337-46.
6. Giovanetti A, Pierdominici M, Mazzetta F, Marziali M, Renzi C, Mileo AM, et al. Unravelling the complexity of T cell abnormalities in common variable immunodefiency. J Immunol. 2007;178:3932-43.
7. Busse PJ, Farzan S, Cunningham-Rundles C. Pulmonary complications of common variable immunodeficiency. Ann Allergy Asthma Immunol. 2007;98:8-11.
8. Knight A, Cunningham Rundles C. Inflammatory and autoimmune complications of common variable immune deficiency. Autoimmun Rev. 2006;5:156-9.
9. Mannon PJ, Fuss IJ, Friend J, Hornung R, Yang Z, Yi C, et al. Excess IL-12 but not IL-23 accompanies the inflammatory bowel disease associated with common variable immunodeficiency. Gastroenterology. 2006;13:748-56.
10. Malamut G, Verkarre V, Suarez F, Villard JF, Lascaux AS, Cosnes J, et al. The enteropathy associated with common variable immunodeficiency: the delineated frontiers with celiac disease. Am J Gastroenteropathy. 2010;105:2262-75.
11. Malamut G, Ziol M, Suarez F, Beaugrand M, Viallard JF, Lascaus AS, et al. Nodular regenerative hyperplasia: the main liver disease in patients with primary hypogammaglobulinemia and hepatic abnormalities. J Hepatol. 2008;48:74-82.
12. Ward C, Lucas M, Piris J, Collier J, Chapel H. Abnormal liver function in common variable immunodeficiency disorders due to nodular regenerative hyperplasia. Clin Exp Immunol. 2008;153:331-7.
13. Wanless IR. Micronuodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules. Hepatology. 1990;11:787-97.
14. Reshamwala PA, Kleiner DE, Heller T. Nodular regenerative hyperplasia: not all nodules are created equal. Hepatology. 2006;44:7-14.
15. Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, Wu J, et al. Interleukin-22, a T(H) 17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature. 2007;445:648-51.
16. Lopatin U, Yao X, Williams RK, Blessing JJ, Dale JK, Wong D, et al. Increases in circulating and lymphoid tissue interleukin-10 in autoimmune lymphoproliferative syndrome are associated with disease expression. Blood. 2001;97:3161-70.
17. Quintanilla-Martinez L, Kumar S, Fend F, Reyes E, Teruya-Feldstein J, Kingma DW, et al. Fulminant EBV(+) T-cell lymphoproliferative disorder following acute/chronic EBV infection: a distinct clinicopathologic syndrome. Blood. 2000;96:443-51.
18. Conley ME, Notarangelo LD, Etzioni A. Diagnostic criteria for primary immunodeficiencies. Representing PAGID (Pan-American group for immunodeficiency) and ESID (European society for immunodeficiencies). Clin Immunol. 1999;93:190-7.
19. Nzeako UC, Goodman ZD, Ishak KG. Hepatocellular carcinoma and nodular regenerative hyperplasia: possible pathogenic relationship. Am J Gastroenterol. 1996;91:879-84.
20. Ravindran J, Gillis D, Rowland R, Heddle R. Common variable immunodeficiency associated with nodular regenerative hyperplasia of the liver. Aust NZ J Med. 1995;25:741.
21. Ardeniz O, Cunningham-Rundles C. Granulomatous disease in common variable immunodeficiency. Clin Immunol. 2009;133:198-207.
22. Razvi S, Schneider L, Jonas MM, Cunningham-Rundles C. Outcome of intravenous immunoglobulin-transmitted hepatitis C virus infection in primary immunodeficiency. Clin Immunol. 2001;101:284-8.
23. Shimamatsu K, Wanless IR. Role of ischemia in causing apoptosis, atrophy, and nodular hyperplasia in human liver. Hepatology. 1997;26:343-50.
24. Ziol M, Poirel H, Koutchou GN, Boyer O, Mohand D, Mouthon L, et al. Intrasinusoidal cytotoxic CD8+ T cells in nodular regenerative hyperplasia of the liver. Hum Pathol. 2004;35:1241-51.