Engineered nanomaterial impact in the liver following exposure via an intravenous route-the role of polymorphonuclear leukocytes and gene expression in the organ

Journal of Nanomedicine and Nanotechnology

Volumn 4, Issue 1, 2013, Pages

  Kermanizadeh, Ali ^a   Brown, David M ^a   Hutchison, Gary R ^b   Stone, Vicki ^a  

^a HERIOT WATT UNIVERSITY   (United Kingdom)

^b EDINBURGH NAPIER UNIVERSITY   (United Kingdom)

Author keywords

Gene expression; Liver; Nanomaterials; Neutrophils; Tissue migration

Indexed keywords

ALBUMIN; CARBON NANOTUBE; COMPLEMENT COMPONENT C3; CXCL2 CHEMOKINE; FAS LIGAND; GLUTATHIONE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 6; MYELOPEROXIDASE; NANOMATERIAL; SILVER; TITANIUM DIOXIDE; TUMOR NECROSIS FACTOR ALPHA; ZINC OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

EID: 84877994043     PISSN: None     EISSN: 21577439     Source Type: Journal    
DOI: 10.4172/2157-7439.1000157     Document Type: Article

References (38)

1. Maynard AD, Aitkin RJ, Butz T, Colvin V, Donaldson K, et al. (2004) Safe handling of nanotechnology. Nature 444: 267-269.
2. Oberdorster G, Oberdorster E, Oberdorster J (2005) Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113: 823-839.
3. http://www.nanotechproject.org/inventories/consumer/browse/products/
4. Ken D, Vicki S (2003) Current hypothesis on mechanisms of toxicity of ultrafine particles. Annali dell'Istituto Superiore di Sanità 39: 405-410.
5. Nel A, Xia T, Madler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311: 622-627.
6. Papp T, Schiffmann D, Weiss D, Castronova V, Vallyathan V, et al. (2008) Human health implications of nonmaterial exposure. Nanotoxicology 2: 9-27.
7. Chen C, Zhang P, Hou X, Chai Z (1999) Sub-cellular distribution of selenium and Se-containing proteins in human liver. Biochim Biophys Acta 1427: 205-215.
8. Diesen DL, Kuo PC (2010) Nitric Oxide and redox regulation in the liver: Part I. General considerations and redox Biology in Hepatitis. J Surg Res 162: 95-109.
9. Sadauskas E, Jacobson NR, Danscher G, Soltenberg M, Larsen A, et al. (2009) Bio-disruption of gold nanoparticles in mouse lung following intratracheal instillation. Chemistry Central Journal 3: 16-23.
10. Semmler-Behnke M, Kreyling WG, Lipka J, Fertsch S, Wenk A, et al. (2008) Bio-distribution of 1.4 and 18-nm gold particles in rats. Small 12: 2108-2111.
11. Kmiec Z (2001) Cooperation of liver cells in health and disease. Adv Anat Embryol Cell Biol 161: 109-113.
12. Freitas M, Lima JLFC, Fernandes E (2009) Optical probes for detection and quantification of neutrophils' oxidative burst. A review. Anal Chim Acta 649: 8-23.
13. Quinn MT, Gauss KA (2004) Structure and regulation of neutrophil respiratory burst oxidase: Comparison with nonphagocyte oxidases. J Leukoc Biol 76: 760-781.
14. Nauseef WM (2007) How human neutrophils kill and degrade microbes: an integrated view. Immunol Rev 219: 88-102.
15. Delpino MV, Barrionuevo P, Scian R, Fossati CA, Balsi PC (2010) Brucella-infected heaptocytes mediate potentially tissue-damaging immune responses. Journal of Hepatology 53: 145-54.
16. Kermanizadeh A, Pojana G, Gaiser BK, Birkedal R, Bilaničová D, et al. (2012) In vitro assessment of engineered nanomaterials using C3A cells: Cytotoxicity, pro-inflammatory cytokines and function markers. Nanotoxicology.
17. Jacobsen NR, Pojano G, Wallin, H, Jensen KA (2012) Nanomaterial dispersion protocol for toxicological studies in ENPRA. Internal ENPRA Project Report. The National Research Centre for the Working Environment.
18. Kermanizadeh A, Gaiser BK, Hutchison GR, Stone V (2012) An in vitro liver model-assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanoparticles. Particle and Fibre Toxicology.
19. Kermanizadeh A, Gaiser BK, Ward MB, Stone V (2012) Primary human hepatocytes vs. hepatic cell line-assessing their suitability for in vitro nanotoxicology. Nanotoxicology.
20. Ding Y, Zhao L, Mei H, Zhang SL, Huang ZH, et al. (2008) Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway. Eur J Pharmacol 590: 377-386.
21. Ivanov S, Zhuravsky S, Yukina G, Tomson V, Korolov D, et al. (2012) In vivo toxicity of intravenously administered silica and silicon nanoparticles. Materials 5: 1873-1889.
22. Tan YK, Best SL, Donnelly C, Olweny E, Kapur P, et al. (2012) Novel iron oxide microparticles used to render stone fragments paramagnetic: assessment of toxicity in a murine model.
23. Bajt ML, Farhood A, Jaeschke H (2001) Effects of CXC chemokines on neutrophil activation and sequestration in hepatic vasculature. Am J Physiol Gastrointest Liver Physiol 281: 1188-1195.
24. Ramaiah SK, Jaeschke H (2007) Role of neutrophils in the pathogenesis of acute inflammatory liver injury. Toxicol Pathol 35: 456-766.
25. Krishnamurphy D, Starkl P, Szalai K, Roth-Walter F, Diesner SC, et al. (2012) Monitoring neutrophils and platelets during casein-induced anaphylaxis in an experimental BALB/c mouse model. Clin Exp Allergy 42: 1119-1128.
26. Nishiura H (2013) The alternative C5a receptor function. Adv Exp Med Biol 734: 111-121.
27. Wigenstam E, Jonasson S, Koch B, Bucht A (2012) Corticosteroid treatment inhibits airway hyper responsiveness and lung injury in a murine model of chemical-induced airway inflammation. Toxicology 301: 66-71.
28. Duffin R, Gilmour PS, Schins RPF, Clouter A, Guy K, et al. (2001) Alminium lactate treatment of DQ12 quartz inhibits its ability to cause inflammation, chemokine expression and nuclear factor-kappa B activation. Toxicol Appl Pharmacol 176: 10-17.
29. Bautista A (2002) Netrophilic infiltration in alcoholic hepatitis. Alcohol 27: 17-21.
30. Sahu A, Lambris JD (2001) Structure and biology of complent protein C3, a connecting link between the innate and acquired immunity. Immunol Rev 180: 35-48.
31. Hertle E, van Greevenbroek MMJ, Stehouwer CDA (2012) Complement C3: an emerging risk factor in cardiometabolic disease. Diabetologica 55: 881-884.
32. Kishimoto T, Akira S, Narazaki M, Taga T (1995) Interleukin-6 family of cytokines and gp130. Blood 86: 1243-1254.
33. Poli V, Cortese R (1989) Interleukin 6 induces a liver-specific nuclear protein that binds to the promoter of acute-phase genes. Proc Natl Acad Sci U S A 86: 8202-8206.
34. Moore KW, Malefyt R, Coffman RL, O'Garra A (2001) Interluekin-10 and the interluekin-10 receptor. Annu Rev Immunol 19: 683-765.
35. Mocellin S, Panelli MC, Wang E, Nagorsen D, Marincola FM (2004) The dual role of IL-10. Trends Immunol 24: 36-43.
36. Zamjahn JB, Quinton LJ, Mack JC, Frevert CW, Nelson S, et al. (2011) Differential flux of macrophage inflammatory protein-2 and cytokine-induced neutrophil chemoattractant from the lung after intrapulmonary delivery. AJP-Lung Physiol 301: L568-L574.
37. McIntyre TM (2012) Bioactive oxidatively truncated phospholipids in inflammation and apoptosis: Formation, targets, and inactivation. Biochim Biophys Acta 1818: 2456-2464.
38. Yang PY, Almofti MR, Lu L, Kang H, Zhang J, et al. (2005) Reduction of atherosclerosis in cholestrol-fed rabbits and decrease of expressions of intracellular adhesion molecule-1 and vascular endothelial growth factor in foam cells by a water-soluble fraction of Polygonum multiflorum. J Pharmacol Sci 99: 294-300.