Microinvasion of high-grade pancreatic intraepithelial neoplasia

Case Reports in Gastroenterology

Volumn 7, Issue 1, 2013, Pages 30-36

  Kawada, Natsuko ^a   Uehara, Hiroyuki ^a   Takada, Ryoji ^a   Yamai, Takuo ^a   Fukutake, Nobuyasu ^a   Katayama, Kazuhiro ^a   Takenaka, Akemi ^a   Nagata, Shigenori ^a   Tomita, Yasuhiko ^a  

^a OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

Microinvasion; PanIN 3; Precursor lesion

Indexed keywords

ACUTE PANCREATITIS; AGED; ARTICLE; BASEMENT MEMBRANE; BODY MASS; BREAST CARCINOMA; CANCER DIAGNOSIS; CANCER SIZE; CANCER STAGING; CANCER SURGERY; CASE REPORT; CONSENSUS; CYTOLOGY; DISEASE DURATION; ENDOSCOPIC ECHOGRAPHY; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; MICROSCOPY; OUTCOME ASSESSMENT; PANCREAS ADENOCARCINOMA; PANCREAS JUICE; PANCREAS RESECTION; PANCREATITIS; PRIORITY JOURNAL; RECURRENT DISEASE; TUMOR INVASION; CANCER CYTODIAGNOSIS; CANCER GRADING; COMPUTER ASSISTED TOMOGRAPHY; HIGH GRADE PANCREATIC INTRAEPITHELIAL NEOPLASIA; HISTOPATHOLOGY; PANCREAS ADENOMA; PANCREAS DUCT; PANCREAS DUCT STENOSIS;

AMYLASE;

EID: 84877988602     PISSN: None     EISSN: 16620631     Source Type: Journal    
DOI: 10.1159/000346693     Document Type: Article

References (21)

1. Hruban RH, Adsay NV, Albores-Saavedea J, et al: Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic ductal lesions. Am J Surg Pathol 2001;25:579-586.
2. Andea A, Sarkar F, Adsay NV: Clinicopathological correlates of pancreatic intraepithelial neoplasia: a comparative analysis of 82 cases with and 152 cases without pancreatic ductal adenocarcinoma. Mod Pathol 2003;16:996-1006.
3. Recavarren C, Labow DM, Liang J, et al: Histologic characteristics of pancreatic intraepithelial neoplasia associated with different pancreatic lesions. Hum Pathol 2011;42:18-24.
4. Takaori K, Kobayashi Y, Matsusue S, et al: Clinicopathological features of pancreatic intraepithelial neoplasias and their relationship to intraductal papillary-mucinous tumors. J Hepatobiliary Pancreat Surg 2003;10:125-136.
5. McCarthy DM, Brat DJ, Wilentz RE, et al: Pancreatic intraepithelial neoplasia and infiltrating adenocarcinoma: analysis of progression and recurrence by DPC4 immunohistochemical labeling. Hum Pathol 2001;32:638-642.
6. Wilentz RE, Iacobuzio-Donahue C, Argani P, et al: Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression. Cancer Res 2000;60:2002-2006.
7. Fukushima N, Sato N, Ueki T, et al: Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma. Am J Pathol 2002;160:1573-1581.
8. Sato N, Fukushima N, Hruban RH, et al: CpG island methylation profile of pancreatic intraepithelial neoplasia. Mod Pathol 2008;21:238-244.
9. Lohr M, Kloeppel G, Maisonneuve P, et al: Frequency of K-ras mutations in pancreatic intraductal neoplasia associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: a metaanalysis. Neoplasia 2005;7:17-23.
10. Hruban RH, Takaori K, Klimstran DS, et al: An illustrated consensus on the classification of pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasms (IPMNs). Am J Surg Pathol 2004;28:977-987.
11. Suzuki Y, Atomi Y, Sugiyama M: Cystic neoplasm of the pancreas: a Japanese multi-institutional study of intraductal papillary mucinous tumor and mucinous cystic tumor. Pancreas 2004;28:241-246.
12. Nakagohri T, Asano T, Kenmochi T, et al: Long-term surgical outcome of noninvasive and minimally invasive intraductal papillary mucinous adenocarcinoma of the pancreas. World J Surg 2002;26:1166-1169.
13. Yamao K, Ohashi K, Nakamura T, et al: The prognosis of intraductal papillary mucinous tumors of the pancreas. Hepatogastroenterology 2000;47:1129-1134.
14. International Agency for Research on Cancer: WHO Classification of Tumours of the Digestive System, ed 4. Lyon, 2010.
15. Japan Pancreas Society: Classification of Pancreatic Cancer, ed 6. Tokyo, Kanehara, 2003.
16. Nara S, Shimada K, Kosuge T, et al: Minimally invasive intraductal papillary-mucinous carcinoma of pancreas: clinicopathologic study of 104 intraductal papillary-mucinous neoplasms. Am J Surg Pathol 2008;32:243-255.
17. Kim J, Jang KT, Park SM, et al: Prognostic relevance of pathologic subtypes and minimal invasion in intraductal papillary mucinous neoplasms of the pancreas. Tumour Biol 2011;32:535-542.
18. Naito Y, Eriguchi N, Kume T, et al: Multi-centric pancreatic cancer without PanIN lesion. J Hepatobiliary Pancreat Surg 2009;16:699-703.
19. Izumi S, Nakamura S, Mano S, et al: Resection of four synchronous invasive ductal carcinomas in the pancreas head and body associated with pancreatic intraepithelial neoplasia: report of a case. Surg Today 2009;39:1091-1097.
20. Takaori K, Matsusue S, Fujikawa T, et al: Carcinoma in situ of the pancreas associated with localized fibrosis: a clue to early detection of neoplastic lesions arising from pancreatic ducts. Pancreas 1998;17:102-105.
21. Tanaka S, Nakao M, Ioka T, et al: Slight dilatation of the main pancreatic duct and presence of pancreatic cysts as predictive signs of pancreatic cancer: a prospective study. Radiology 2010;254:965-972.