A randomized controlled trial of exercise training on cardiovascular and autonomic function among renal transplant recipients

Nephrology Dialysis Transplantation

Volumn 28, Issue 5, 2013, Pages 1294-1305

  Kouidi, Evangelia ^a   Vergoulas, George ^b   Anifanti, Maria ^a   Deligiannis, Asterios ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b Aristotle University and Hippokration General Hospital   (Greece)

Author keywords

baroreflex sensitivity; cardiac autonomic function; exercise training; heart rate variability; renal transplantation

Indexed keywords

ADULT; ARTERIAL BAROREFLEX SENSITIVITY; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BAROREFLEX EFFECTIVENESS INDEX; CARDIOVASCULAR FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; EXERCISE; EXERCISE TEST; FEMALE; FOLLOW UP; GRAFT RECIPIENT; HEART RATE VARIABILITY; HOLTER MONITORING; HUMAN; KIDNEY TRANSPLANTATION; MALE; OXYGEN CONSUMPTION; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEDENTARY LIFESTYLE; TILT TABLE TEST;

EID: 84877979550     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs455     Document Type: Article

References (53)

1. Agarwal A, Anand IS, Sakhuja V et al. Effect of dialysis and renal transplantation on autonomic dysfunction in chronic renal failure. Kidney Int 1991; 40: 489-495
2. Yildiz A, Sever MS, Demirel S et al. Improvement of uremic auto-nomic dysfunction after renal transplantation: a heart rate variability study. Nephron 1998; 80: 57-60
3. Rubinger D, Sapoznikov D, Pollak A et al. Heart rate variability during chronic hemodialysis and after renal transplantation: studies in patients without and with systemic amyloidosis. J Am Soc Nephrol 1999; 10: 1972-1981
4. Gerhardt U, Riedasch M, Steinmetz M et al. Kidney transplantation improves baroreceptor sensitivity. Int J Cardiol 1999; 70: 233-239
5. Cashion AK, Hathaway DK, Milstead EJ et al. Changes in patterns of 24-hr heart rate variability after kidney and kidney-pancreas transplant. Transplantation 1999; 68: 1846-1850
6. Rubinger D, Backenroth R, Sapoznikov D. Restoration of barore-flex function in patients with end-stage renal disease after renal transplantation. Nephrol Dial Transplant 2009; 24: 1305-1313
7. Hildreth CM. Prognostic indicators of cardiovascular risk in renal disease. Front Physiol 2011; 2: 121
8. Kurata C, Uehara A, Ishikawa A. Improvement of cardiac sympathetic innervation by renal transplantation. J Nucl Med 2004; 45: 1114-1120
9. Yang YW, Wu CH, Tsai MK et al. Heart rate variability during hemodialysis and following renal transplantation. Transplant Proc 2010; 42: 1637-1640
10. Solders G, Tydén G, Persson A et al. Improvement of nerve conduction in diabetic neuropathy. A follow-up study 4 yr after combined pancreatic and renal transplantation. Diabetes 1992; 41: 946-951
11. Hausberg M, Kosch M, Harmelink P et al. Sympathetic nerve activity in end-stage renal disease. Circulation 2002; 106: 1974-1979
12. Hausberg M, Lang D, Levers A et al. Sympathetic nerve activity in renal transplant patients before and after withdrawal of cyclos-porine. J Hypertens 2006; 24: 957-964
13. McGregor DO, Olsson C, Lynn KL. Autonomic dysfunction and ambulatory blood pressure in renal transplant recipients. Transplantation 2001; 71: 1277-1281
14. Task Force of the ESC and NASPE. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Circulation 1996; 93: 1043-1065
15. Bavanandan S, Ajayi S, Fentum B et al. Cardiac baroreceptor sensitivity: a prognostic marker in predialysis chronic kidney disease patients. Kidney Int 2005; 67: 1019-1027
16. Johansson M, Gao SA, Friberg P et al. Baroreflex effectiveness index and baroreflex sensitivity predict all-cause mortality and sudden death in hypertensive patients with chronic renal failure. J Hypertens 2007; 25: 163-168
17. Chandra P, Sands RL, Gillespie BW et al. Predictors of heart rate variability and its prognostic significance in chronic kidney disease. Nephrol Dial Transplant 2012; 27: 700-709
18. Mameletzi D, Kouidi E, Koutlianos N et al. Effects of long-term exercise training on cardiac baroreflex sensitivity in patients with coronary artery disease: a randomized controlled trial. Clin Rehabil 2011; 25: 217-227
19. Tygesen H, Wettervik C, Wennerblom B. Intensive home-based exercise training in cardiac rehabilitation increases exercise capacity and heart rate variability. Int J Cardiol 2001; 79: 175-182
20. Larsen AI, Gjesdal K, Hall C et al. Effect of exercise training in patients with heart failure: a pilot study on autonomic balance assessed by heart rate variability. Eur J Cardiovasc Prev Rehabil 2004; 11: 162-167
21. Costes F, Roche F, Pichot V et al. Influence of exercise training on cardiac baroreflex sensitivity in patients with COPD. Eur Respir J 2004; 23: 396-401
22. Loimaala A, Huikuri HV, Kööbi T et al. Exercise training improves baroreflex sensitivity in type 2 diabetes. Diabetes 2003; 52: 1837-1842
23. Pagkalos M, Koutlianos N, Kouidi E et al. Heart rate variability modifications following exercise training in type 2 diabetic patients with definite cardiac autonomic neuropathy. Br J Sports Med 2008; 42: 47-54
24. Deligiannis A, Kouidi E, Tourkantonis A. Effects of physical training on heart rate variability in patients on hemodialysis. Am J Cardiol 1999; 84: 197-202
25. Petraki M, Kouidi E, Grekas D et al. Effects of exercise training during hemodialysis on cardiac baroreflex sensitivity. Clin Nephrol 2008; 70: 210-219
26. Kouidi EJ, Grekas DM, Deligiannis AP. Effects of exercise training on noninvasive cardiac measures in patients undergoing long-term hemodialysis: a randomized controlled trial. Am J Kidney Dis 2009; 54: 511-521
27. Milani RV, Lavie CJ, Mehra MR et al. Understanding the basics of cardiopulmonary exercise testing. Mayo Clin Proc 2006; 81: 1603-1611
28. Lavie CJ, Thomas RJ, Squires RW et al. Exercise training and cardiac rehabilitation in primary and secondary prevention of coronary heart disease. Mayo Clin Proc 2009; 84: 373-383
29. Kenny RA, O'Shea D, Parry SW. The Newcastle protocols for head-up tilt table testing in the diagnosis of vasovagal syncope, carotid sinus hypersensitivity, and related disorders. Heart 2000; 83: 564-569
30. Tory K, Süveges Z, Horváth E et al. Autonomic dysfunction in uremia assessed by heart rate variability. Pediatr Nephrol 2003; 18: 1167-1171
31. Studinger P, Lénárd Z, Mersich B et al. Determinants of barore-flex function in juvenile end-stage renal disease. Kidney Int 2006; 69: 2236-2242
32. Parisotto V, Lima EM, Silva JM et al. Cardiac sympathetic dysau-tonomia in children with chronic kidney disease. J Nucl Cardiol 2008; 15: 246-254
33. Perini R, Veicsteinas A. Heart rate variability and autonomic activity at rest and during exercise in various physiological conditions. Eur J Appl Physiol 2003; 90: 317-325
34. Gribbin B, Pickering TG, Sleight P et al. Effect of age and high blood pressure on baroreflex sensitivity in man. Circ Res 1971; 29: 424-431
35. Chesterton LJ, Sigrist MK, Bennett T et al. Reduced baroreflex sensitivity is associated with increased vascular calcification and arterial stiffness. Nephrol Dial Transplant 2005; 20: 1140-1147
36. Velez-Roa S, Neubauer J, Wissing M et al. Acute arterio-venous fistula occlusion decreases sympathetic activity and improves bar-oreflex control in kidney transplanted patients. Nephrol Dial Transplant 2004; 19: 1606-1612
37. Kempeneers G, Noakes TD, van Zyl-Smit R et al. Skeletal muscle limits the exercise tolerance of renal transplant recipients: effects of a graded exercise training program. Am J Kidney Dis 1990; 16: 57-65
38. van den Ham EC, Kooman JP, Schols AM et al. The functional, metabolic, and anabolic responses to exercise training in renal transplant and hemodialysis patients. Transplantation 2007; 83: 1059-1068
39. Armstrong K, Rakhit D, Jeffriess L et al. Cardiorespiratory fitness is related to physical inactivity, metabolic risk factors, and atherosclerotic burden in glucose-intolerant renal transplant recipients. Clin J Am Soc Nephrol 2006; 1: 1275-1283
40. Painter P, Krasnoff JB, Kuskowski M et al. Effects of modality change and transplant on peak oxygen uptake in patients with kidney failure. Am J Kidney Dis 2011; 57: 113-122
41. Takeyama J, Itoh H, Kato M et al. Effects of physical training on the recovery of the autonomic nervous activity during exercise after coronary artery bypass grafting: effects of physical training after CABG. Jpn Circ J 2000; 64: 809-813
42. Galetta F, Franzoni F, Femia FR et al. Lifelong physical training prevents the age-related impairment of heart rate variability and exercise capacity in elderly people. J Sports Med Phys Fitness 2005; 45: 217-221
43. Deley G, Picard G, Taylor JA. Arterial baroreflex control of cardiac vagal outflow in older individuals can be enhanced by aerobic exercise training. Hypertension 2009; 53: 826-832
44. Routledge FS, Campbell TS, McFetridge-Durdle JA et al. Improvements in heart rate variability with exercise therapy. Can J Cardiol 2010; 26: 303-312
45. Deligiannis A. Cardiac adaptations following exercise training in hemodialysis patients. Clin Nephrol 2004; 61(Suppl 1): S39-S45.
46. Kouidi E, Karagiannis V, Grekas D et al. Depression, heart rate variability, and exercise training in dialysis patients. Eur J Cardio-vasc Prev Rehabil 2010; 17: 160-167
47. Kramer JM, Beatty JA, Plowey ED et al. Exercise and hypertension: a model for central neural plasticity. Clin Exp Pharmacol Physiol 2002; 29: 122-126
48. Laterza MC, de Matos LD, Trombetta IC et al. Exercise training restores baroreflex sensitivity in never-treated hypertensive patients. Hypertension 2007; 49: 1298-1306
49. Mimura J, Yuasa F, Yuyama R et al. The effect of residential exercise training on baroreflex control of heart rate and sympathetic nerve activity in patients with acute myocardial infarction. Chest 2005; 127: 1108-1115
50. La Rovere MT, Bersano C, Gnemmi M et al. Exercise-induced increase in baroreflex sensitivity predicts improved prognosis after myocardial infarction. Circulation 2002; 106: 945-949
51. Iellamo F. Prognostic role of baroreflex control of heart rate: further insights from dynamic assessment of baroreceptor-cardiac reflex? J Hypertens 2007; 25: 51-53
52. Kouidi E. Central and peripheral adaptations to physical training in patients with end-stage renal disease. Sports Med 2001; 31: 651-665
53. Kouidi E. Exercise training in dialysis patients: why, when, and how? Artif Organs 2002; 26: 1009-1013