Resveratrol inhibits GABAC ρ receptor-mediated ion currents expressed in Xenopus oocytes

Korean Journal of Physiology and Pharmacology

Volumn 17, Issue 2, 2013, Pages 175-180

  Lee, Byung Hwan ^a   Choi, Sun Hye ^a   Hwang, Sung Hee ^a   Kim, Hyeon Joong ^a   Lee, Joon Hee ^b   Nah, Seung Yeol ^a  

^a Konkuk University   (South Korea)

^b Sehan University   (South Korea)

Author keywords

GABAC receptor; Ligand gated ion channel; Resveratrol; Xenopus oocyte

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID C RECEPTOR; 4 AMINOBUTYRIC ACID C RECEPTOR RHO SUBUNIT; RESVERATROL; RNA; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; IC 50; IN VITRO STUDY; INWARD PEAK CURRENT; ION CURRENT; MEMBRANE POTENTIAL; NONHUMAN; OOCYTE; PROTEIN EXPRESSION; XENOPUS LAEVIS;

EID: 84877971908     PISSN: 12264512     EISSN: 20933827     Source Type: Journal    
DOI: 10.4196/kjpp.2013.17.2.175     Document Type: Article

References (30)

1. Jensen ml, Schousboe A, Ahring PK. Charge selectivity of the Cys-loop family of ligand-gated ion channels. J Neurochem. 2005;92:217-225.
2. Bormann J. The 'ABC' of GABA receptors. Trends Pharmacol Sci. 2000;21:16-19. (Pubitemid 30102186)
3. Chebib M, Johnston GA. GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology. J Med Chem. 2000;43:1427-1447. (Pubitemid 30238425)
4. C receptor subunits in native central neurons. J Neurosci. 2004;24:7241-7250.
5. 3H-GABA in nerve terminals of rat cerebral cortex by electron microscopic autoradiography. Nature. 1971;229:628-630.
6. McCabe RT, Wamsley JK. Autoradiographic localization of subcomponents of the macromolecular GABA receptor complex. Life Sci. 1986;39:1937-1945. (Pubitemid 17184808)
7. Wässle H, Koulen P, Brandstätter JH, Fletcher EL, Becker CM. Glycine and GABA receptors in the mammalian retina. Vision Res. 1998;38:1411-1430. (Pubitemid 28239263)
8. McCall MA, Lukasiewicz PD, Gregg RG, Peachey NS. Elimination of the rho1 subunit abolishes GABA(C) receptor expression and alters visual processing in the mouse retina. J Neurosci. 2002;22:4163-4174. (Pubitemid 37465723)
9. Drew CA, Johnston GA, Weatherby RP. Bicuculline-insensitive GABA receptors: studies on the binding of (-)-baclofen to rat cerebellar membranes. Neurosci Lett. 1984;52:317-321. (Pubitemid 15186505)
10. Strata F, Cherubini E. Transient expression of a novel type of GABA response in rat CA3 hippocampal neurones during development. J Physiol. 1994;480:493-503. (Pubitemid 24340952)
11. Johnston GA, Chebib M, Hanrahan JR, Mewett KN. GABA(C) receptors as drug targets. Curr Drug Targets CNS Neurol Disord. 2003;2:260-268.
12. Langcake P, Pryce RJ. A new class of phytoalexins from grapevines. Experientia. 1977;33:151-152.
13. Dudley J, Das S, Mukherjee S, Das DK. Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose. J Nutr Biochem. 2009;20:443-452.
14. Pervaiz S. Resveratrol: from grapevines to mammalian biology. FASEB J. 2003;17:1975-1985. (Pubitemid 37392442)
15. Valenzano DR, Terzibasi E, Genade T, Cattaneo A, Domenici L, Cellerino A. Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Curr Biol. 2006;16:296-300. (Pubitemid 43190229)
16. Chen J, Zhou Y, Mueller-Steiner S, Chen LF, Kwon H, Yi S, Mucke L, Gan L. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. J Biol Chem. 2005;280:40364-40374. (Pubitemid 41779174)
17. West T, Atzeva M, Holtzman DM. Pomegranate polyphenols and resveratrol protect the neonatal brain against hypoxic-ischemic injury. Dev Neurosci. 2007;29:363-372. (Pubitemid 47343690)
18. Raval AP, Dave KR, Pérez-Pinzón MA. Resveratrol mimics ischemic preconditioning in the brain. J Cereb Blood Flow Metab. 2006;26:1141-1147. (Pubitemid 44268176)
19. Lee BH, Hwang SH, Choi SH, Shin TJ, Kang J, Lee SM, Nah SY. Resveratrol enhances 5-hydroxytryptamine type 3A receptor-mediated ion currents: the role of arginine 222 residue in pre-transmembrane domain I. Biol Pharm Bull. 2011;34:523-527.
20. Chan MM. Antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin. Biochem Pharmacol. 2002;63:99-104. (Pubitemid 34158808)
21. Lee BH, Shin TJ, Hwang SH, Choi SH, Kang J, Kim HJ, Park CW, Lee SH, Nah SY. Inhibitory effects of quercetin on muscle-type of nicotinic acetylcholine receptor-mediated ion currents expressed in xenopus oocytes. Korean J Physiol Pharmacol. 2011;15:195-201.
22. Sine SM, Taylor P. Local anesthetics and histrionicotoxin are allosteric inhibitors of the acetylcholine receptor. Studies of clonal muscle cells. J Biol Chem. 1982;257:8106-8104.
23. Heidmann T, Oswald RE, Changeux JP. Multiple sites of action for noncompetitive blockers on acetylcholine receptor rich membrane fragments from torpedo marmorata. Biochemistry. 1983;22:3112-3127. (Pubitemid 13061673)
24. Arias HR. Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor. Mol Membr Biol. 1996;13:1-17.
25. Saleh MC, Connell BJ, Saleh TM. Resveratrol preconditioning induces cellular stress proteins and is mediated via NMDA and estrogen receptors. Neuroscience. 2010;166:445-454.
26. Wu Z, Xu Q, Zhang L, Kong D, Ma R, Wang L. Protective effect of resveratrol againstkainate-induced temporal lobe epilepsy in rats. Neurochem Res. 2009;34:1393-1400.
27. Shinohara Y, Toyohira Y, Ueno S, Liu M, Tsutsui M, Yanagihara N. Effects of resveratrol, a grape polyphenol, on catecholamine secretion and synthesis in cultured bovine adrenal medullary cells. Biochem Pharmacol. 2007;74:1608-1618. (Pubitemid 47614968)
28. Boue-Grabot E, Taupignon A, Tramu G, Garret M. Molecular and electrophysiological evidence for a GABAc receptor in thyrotropin-secreting cells. Endocrinology. 2000;141:1627-1632. (Pubitemid 32274390)
29. Jansen A, Hoepfner M, Herzig KH, Riecken EO, Scherübl H. GABA(C) receptors in neuroendocrine gut cells: a new GABA-binding site in the gut. Pflugers Arch. 2000;441:294-300. (Pubitemid 32128170)
30. Chebib M. GABAC receptor ion channels. Clin Exp Pharmacol Physiol. 2004;31:800-804.