A novel multi-target drug screening strategy directed against key proteins of DAPk family

Combinatorial Chemistry and High Throughput Screening

Volumn 16, Issue 6, 2013, Pages 449-457

  Nair, Syam B ^a   Fayaz, Shaik M ^a   Rajanikant, Golgodu K ^a  

^a NATIONAL INSTITUTE OF TECHNOLOGY CALICUT   (India)

Author keywords

DAPk; DRP1; Merged pharmacophore; Multi target; Polypharmacology; ZIPk

Indexed keywords

AMINO ACID; DEATH ASSOCIATED PROTEIN KINASE; LIGAND; PROTEIN SERINE THREONINE KINASE INHIBITOR;

APOPTOSIS; ARTICLE; BRAIN INJURY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG BINDING SITE; DRUG BIOAVAILABILITY; DRUG SCREENING; EUKARYOTIC CELL; MOLECULAR DOCKING; MOLECULAR INTERACTION; NERVE CELL NECROSIS; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN TARGETING; SEQUENCE ALIGNMENT;

BINDING SITES; CELL DEATH; DEATH-ASSOCIATED PROTEIN KINASES; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; LIGANDS; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84877964920     PISSN: 13862073     EISSN: 18755402     Source Type: Journal    
DOI: 10.2174/1386207311316060005     Document Type: Article

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