The use of albendazole and diammonium glycyrrhizinate in the treatment of eosinophilic meningitis in mice infected with Angiostrongylus cantonensis

Journal of Helminthology

Volumn 87, Issue 1, 2013, Pages 1-11

  Li, Y ^a,b,c   Tang, J P ^a   Chen, D R ^d   Fu, C Y ^a   Wang, P ^a   Li, Z ^a   Wei, W ^a   Li, H ^a   Dong, W Q ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b Wuxi Hospital for Infectious Diseases   (China)

^c LANZHOU UNIVERSITY   (China)

^d Department of Pathology   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE; DEXAMETHASONE; DIAMMONIUM GLYCYRRHIZINATE; EOTAXIN; GLYCYRRHIZIC ACID; IMMUNOGLOBULIN E; INTERLEUKIN 5; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ANGIOSTRONGYLIASIS; ANGIOSTRONGYLUS CANTONENSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BODY WEIGHT; CD4+ CD25+ T LYMPHOCYTE; CONTROLLED STUDY; EOSINOPHIL; EOSINOPHIL MENINGITIS; FEMALE; FLOW CYTOMETRY; HISTOPATHOLOGY; MENINGITIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SURVIVAL TIME; SYMPTOMATOLOGY;

ALBENDAZOLE; ANGIOSTRONGYLUS CANTONENSIS; ANIMALS; ANTHELMINTICS; BODY WEIGHT; DEXAMETHASONE; DISEASE MODELS, ANIMAL; EOSINOPHILIA; FEMALE; GLYCYRRHIZIC ACID; HUMANS; IMMUNOGLOBULIN E; LEUKOCYTE COUNT; MENINGITIS; MICE; MICE, INBRED BALB C; STRONGYLIDA INFECTIONS; SURVIVAL ANALYSIS; T-LYMPHOCYTES, REGULATORY; TREATMENT OUTCOME;

EID: 84877947279     PISSN: 0022149X     EISSN: 14752697     Source Type: Journal    
DOI: 10.1017/S0022149X11000745     Document Type: Article

References (44)

1. Abe, K., Ikeda, T., Wake, K., Sato, T., Sato, T. & Inoue, H. (2008) Glycyrrhizin prevents lipopolysaccharide/D-galactosamine-induced liver injury through down-regulation of matrix metalloproteinase-9 in mice. Journal of Pharmacy and Pharmacology 60, 91-97.
2. Alicata, J.E. (1965) Biology and distribution of the rat lungworm, Angiostrongylus cantonensis, and its relationship to eosinophilic meningoencephalitis and other neurological disorders of man and animals. Advances in Parasitology 3, 223-248.
3. Belkaid, Y. (2007) Regulatory T cells and infection: a dangerous necessity. Nature Reviews Immunology 7, 875-888.
4. Chotmongkol, V., Wongjitrat, C., Sawadpanit, K. & Sawanyawisuth, K. (2004) Treatment of eosinophilic meningitis with a combination of albendazole and corticosteroid. Southeast Asian Journal of Tropical Medicine and Public Health 35, 172-174.
5. Chuang, C.C., Su, K.E., Chen, C.W., Fan, C.K., Lin, F.K., Chen, Y.S. & Du, W.Y. (2010) Anti-CCR3 monoclonal antibody inhibits eosinophil infiltration in Angiostron-gylus cantonensis-infected ICR mice. Acta Tropica 113, 209-213.
6. Chung, L.Y., Chen, C.H., Wang, L.C., Chang, S.J. & Yen, C.M. (2010) Oxidative stress in mice infected with Angiostrongylus cantonensis coincides with enhanced glutathione-dependent enzymes activity. Experimental Parasitology 126, 178-183.
7. Diao, Z., Chen, X., Yin, C., Wang, J., Qi, H. & Ji, A. (2009) Angiostrongylus cantonensis: effect of combination therapy with albendazole and dexamethasone on Th cytokine gene expression in PBMC from patients with eosino-philic meningitis. Experimental Parasitology 123, 1-5.
8. Eamsobhana, P., Lim, P.E., Zhang, H., Gan, X. & Yong, H.S. (2010) Molecular differentiation and phylogenetic relationships of three Angiostrongylus species and Angiostrongylus cantonensis geographical isolates based on a 66-kDa protein gene of A. cantonensis (Nematoda: Angiostrongylidae). Experimental Parasitology 126, 564-569.
9. Fang, R., Nie, H., Wang, Z., Tu, P., Zhou, D., Wang, L., He, L., Zhou, Y. & Zhao, J. (2009) Protective immune response in BALB/c mice induced by a suicidal DNA vaccine of the MIC3 gene of Toxoplasma gondii. Veterinary Parasitology 164, 134-140.
10. Feng, C., Wang, H., Yao, C., Zhang, J. & Tian, Z. (2007) Diammonium glycyrrhizinate, a component of traditional Chinese medicine Gan-Cao, prevents murine T-cell-mediated fulminant hepatitis in IL-10-and IL-6-dependent manners. International Immuno-pharmacology 7, 1292-1298.
11. + regulatory T cells. Nature Immunology 4, 330-336.
12. He, H.J., Lv, Z.Y., Li, Z.Y., Zhang, L.Y., Liao, Q., Zheng, H.Q., Su, W.Y., Rao, S.Q., Yu, X.B. & Wu, Z.D. (2011) Efficacy of combined treatment with albendazole and baicalein against eosinophilic meningitis induced by Angiostrongylus cantonensis in mice. Journal of Helminthology 85, 92-99.
13. Hogan, S.P., Rosenberg, H.F., Moqbel, R., Phipps, S., Foster, P.S., Lacy, P., Kay, A.B. & Rothenberg, M.E. (2008) Eosinophils: biological properties and role in health and disease. Clinical and Experimental Allergy 38, 709-750.
14. Intapan, P.M., Niwattayakul, K., Sawanyawisuth, K., Chotmongkol, V. & Maleewong, W. (2007) Cere-brospinal fluid eotaxin and eotaxin-2 levels in human eosinophilic meningitis associated with angiostron-gyliasis. Cytokine 39, 138-141.
15. Intapan, P.M., Kittimongkolma, S., Niwattayakul, K., Sawanyawisuth, K. & Maleewong, W. (2008) Cere-brospinal fluid cytokine responses in human eosino-philic meningitis associated with angiostrongyliasis. Journal of the Neurological Sciences 267, 17-21.
16. Ismael, A.B., Dimier-Poisson, I., Lebrun, M., Dubremetz, J.F., Bout, D. & Mevelec, M.N. (2006) Mic1-3 knockout of Toxoplasma gondii is a successful vaccine against chronic and congenital toxoplasmosis in mice. Journal of Infectious Diseases 194, 1176-1183.
17. Ismael, A.B., Hedhli, D., Cerede, O., Lebrun, M., Dimier-Poisson, I. & Mevelec, M.N. (2009) Further analysis of protection induced by the MIC3 DNA vaccine against T. gondii: CD4 and CD8 T cells are the major effectors of the MIC3 DNA vaccine-induced protection, both lectin-like and EGF-like domains of MIC3 conferred protection. Vaccine 27, 2959-2966.
18. Jindrak, K. & Alicata, J.E. (1968) Comparative pathology in experimental infection of pigs and calves with larvae of Angiostrongylus cantonensis. Journal of Comparative Pathology 78, 371-382.
19. Kwon, O.J., Au, B.T., Collins, P.D., Adcock, I.M., Mak, J.C., Robbins, R.R., Chung, K.F. & Barnes, P.J. (1994) Tumor necrosis factor-induced interleukin-8 expression in cultured human airway epithelial cells. American Journal of Physiology 267, L398-L405.
20. Lai, S.C., Chen, K.M., Chang, Y.H. & Lee, H.H. (2008) Comparative efficacies of albendazole and the Chinese herbal medicine long-dan-xie-gan-tan, used alone or in combination, in the treatment of experimental eosinophilic meningitis induced by Angiostrongylus cantonensis. Annals of Tropical Medicine and Parasitology 102, 143-150.
21. Lan, K.P. & Lai, S.C. (2009) Differences of proteolytic enzymes and pathological changes in permissive and nonpermissive animal hosts for Angiostrongylus cantonensis infection. Veterinary Parasitology 165, 265-272.
22. Lin, K.Y., Chen, K.M., Lan, K.P., Lee, H.H. & Lai, S.C. (2010) Alterations of myelin proteins in inflammatory demyelination of BALB/c mice caused by Angiostrongylus cantonensis. Veterinary Parasitology 171, 74-80.
23. Matsui, S., Matsumoto, H., Sonoda, Y., Ando, K., Aizu-Yokota, E., Sato, T. & Kasahara, T. (2004) Glycyrrhizin and related compounds down-regulate production of inflammatory chemokines IL-8 and eotaxin 1 in a human lung fibroblast cell line. International Immunopharmacology 4, 1633-1644.
24. Matsui, S., Sonoda, Y., Sekiya, T., Aizu-Yokota, E. & Kasahara, T. (2006) Glycyrrhizin derivative inhibits eotaxin 1 production via STAT6 in human lung fibro-blasts. International Immunopharmacology 6, 369-375.
25. Narala, V.R., Ranga, R., Smith, M.R., Berlin, A.A., Standiford, T.J., Lukacs, N.W. & Reddy, R.C. (2007) Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma. Respiritory Research 8, 90.
26. Ni, Y.F., Kuai, J.K., Lu, Z.F., Yang, G.D., Fu, H.Y., Wang, J., Tian, F., Yan, X.L., Zhao, Y.C., Wang, Y.J. & Jiang, T. (2011) Glycyrrhizin treatment is associated with attenuation of lipopolysaccharide-induced acute lung injury by inhibiting cyclooxygenase-2 and inducible nitric oxide synthase expression. Journal of Surgical Research 165, e29-e35.
27. Padilla-Docal, B., Dorta-Contreras, A.J., Bu-Coifiu-Fanego, R., Rodriguez-Rey, A., Gutierrez-Hernandez, J.C. & De Paula-Almeida, S.O. (2010) Reibergram of intrathecal synthesis of C4 in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis. American Journal of Tropical Medicine and Hygiene 82, 1094-1098.
28. Parsons, J.C. & Grieve, R.B. (1990) Effect of egg dosage and host genotype on liver trapping in murine larval toxocariasis. Journal of Parasitology 76, 53-58.
29. + suppressor T cells regulate pathogen induced inflammation and disease. FEMS Immunology and Medical Microbiology 44, 121-127.
30. Ram, A., Mabalirajan, U., Das, M., Bhattacharya, I., Dinda, A.K., Gangal, S.V. & Ghosh, B. (2006) Glycyrrhizin alleviates experimental allergic asthma in mice. International Immunopharmacology 6, 1468-1477.
31. Ramos, A.L., Discipio, R.G. & Ferreira, A.M. (2006) Eosinophil cationic protein damages protoscoleces in vitro and is present in the hydatid cyst. Parasite Immunology 28, 347-355.
32. Rosenberg, H.F., Phipps, S. & Foster, P.S. (2007) Eosinophil trafficking in allergy and asthma. Journal of Allergy and Clinical Immunology 119, 1303-1312.
33. Sasaki, O., Sugaya, H., Ishida, K. & Yoshimura, K. (1993) Ablation of eosinophils with anti-IL-5 antibody enhances the survival of intracranial worms of Angiostrongylus cantonensis in the mouse. Parasite Immunology 15, 349-354.
34. Sato, H., Goto, W., Yamamura, J., Kurokawa, M., Kageyama, S., Takahara, T., Watanabe, A. & Shiraki, K. (1996) Therapeutic basis of glycyrrhizin on chronic hepatitis B. Antiviral Research 30, 171-177.
35. Seminario, M.C., Saini, S.S. Jr, Macglashan, D. & Bochner, B.S. (1999) Intracellular expression and release of Fc epsilon RI alpha by human eosinophils. Journal of Immunology 162, 6893-6900.
36. Shaio, M.F., Hou, S.C., Chen, J.G., Wu, C.C., Yang, K.D. & Chang, F.Y. (1990) Immunoglobulin G-dependent classical complement pathway activation in neutro-phil-mediated cytotoxicity to infective larvae of Angiostrongylus cantonensis. Annals of Tropical Medicine and Parasitology 84, 185-191.
37. Someya, A., Nishijima, K., Nunoi, H., Irie, S. & Nagaoka, I. (1997) Study on the superoxide-producing enzyme of eosinophils and neutrophils- comparison of the NADPH oxidase components. Archives of Biochemistry and Biophysics 345, 207-213.
38. Song, L.J., Wang, Z.X., Chi, B.R. & Yang, G.Z. (2007) Regulatory effect of diammonium glycyrrhizinate on Th1/Th2 deviation in bronchial asthma: experiment with rats. Zhonghua Yi Xue Za Zhi 87, 2865-2867 (in Chinese).
39. Takei, H., Baba, Y., Hisatsune, A., Katsuki, H., Miyata, T., Yokomizo, K. & Isohama, Y. (2008) Glycyrrhizin inhibits interleukin-8 production and nuclear factor-kappaB activity in lung epithelial cells, but not through glucocorticoid receptors. Journal of Pharmacological Sciences 106, 460-468.
40. Tu, W.C. & Lai, S.C. (2006) Angiostrongylus cantonensis: efficacy of albendazole-dexamethasone co-therapy against infection-induced plasminogen activators and eosinophilic meningitis. Experimental Parasitology 113, 8-15.
41. Wang, J.M., Rambaldi, A., Biondi, A., Chen, Z.G., Sanderson, C.J. & Mantovani, A. (1989) Recombinant human interleukin 5 is a selective eosinophil chemo-attractant. European Journal of Immunology 19, 701-705.
42. Wang, Q.P., Lai, D.H., Zhu, X.Q., Chen, X.G. & Lun, Z.R. (2008) Human angiostrongyliasis. Lancet Infectious Diseases 8, 621-630.
43. Yamaguchi, Y., Hayashi, Y., Sugama, Y., Miura, Y., Kasahara, T., Kitamura, S., Torisu, M., Mita, S., Tominaga, A. & Takatsu, K. (1988) Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor. Journal of Experimental Medicine 167, 1737-1742.
44. Yen, C.M. & Chen, E.R. (1991) Detection of antibodies to Angiostrongylus cantonensis in serum and cerebrospinal fluid of patients with eosinophilic meningitis. International Journal for Parasitology 21, 17-21.