Human fetal hepatic progenitor cells are distinct from, but closely related to, hematopoietic stem/progenitor cells

Stem Cells

Volumn 31, Issue 6, 2013, Pages 1160-1169

  Chen, Qingfeng ^a,b   Khoury, Maroun ^a   Limmon, Gino ^a   Choolani, Mahesh ^c   Chan, Jerry K Y ^c,d,e   Chen, Jianzhu ^a,f  

^a SINGAPORE MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY   (Singapore)

^b INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d KK WOMEN'S AND CHILDREN'S HOSPITAL   (Singapore)

^e DUKE NUS MEDICAL SCHOOL   (Singapore)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Hematopoietic stem progenitor cell; Hepatic progenitor cell; Humanized mouse; Liver reconstitution; Surface phenotype; Transcription profiling

Indexed keywords

5' NUCLEOTIDASE; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; ALBUMIN; ALPHA FETOPROTEIN; CD133 ANTIGEN; CD14 ANTIGEN; CD24 ANTIGEN; CD45 ANTIGEN; CD97 ANTIGEN; CYTOKERATIN 19; CYTOKERATIN 7; ENDOGLIN; EPITHELIAL CELL ADHESION MOLECULE; STEM CELL FACTOR RECEPTOR; THY 1 ANTIGEN; UVOMORULIN; VIMENTIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CD34 SELECTION; CELL DIFFERENTIATION; CELL FRACTIONATION; CELL MATURATION; COLONY FORMING UNIT; DENDRITIC CELL; ENGRAFTMENT; FETUS; FETUS LIVER; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER STEM CELL; MACROPHAGE; MONOCYTE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PROTEIN EXPRESSION; STEM CELL; T LYMPHOCYTE;

ALBUMINS; ALPHA-FETOPROTEINS; ANIMALS; ANTIGENS, CD; ANTIGENS, CD34; ANTIGENS, NEOPLASM; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; DENDRITIC CELLS; GLYCOPROTEINS; HEMATOPOIETIC STEM CELLS; HEPATOCYTES; HUMANS; LIVER; LYMPHOCYTES; MICE; MICE, INBRED NOD; MICE, SCID; MONOCYTES; PEPTIDES; STEM CELLS; TRANSCRIPTION, GENETIC; VIMENTIN;

EID: 84877934814     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1359     Document Type: Article

References (34)

1. Yin AH, Miraglia S, Zanjani ED et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 1997;90:5002-5012. (Pubitemid 28007217)
2. Legrand N, Weijer K, Spits H. Experimental models to study development and function of the human immune system in vivo. J Immunol 2006;176:2053-2058. (Pubitemid 43201649)
3. Gimeno R, Weijer K, Voordouw A et al. Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: Functional inactivation of p53 in developing T cells. Blood 2004;104:3886-3893. (Pubitemid 39620134)
4. Petersen BE, Goff JP, Greenberger JS et al. Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat. Hepatology 1998;27:433-445. (Pubitemid 28081058)
5. Fiegel HC, Park JJ, Lioznov MV et al. Characterization of cell types during rat liver development. Hepatology 2003;37:148-154. (Pubitemid 36042155)
6. Fujio K, Evarts RP, Hu Z et al. Expression of stem cell factor and its receptor, c-kit, during liver regeneration from putative stem cells in adult rat. Lab Invest 1994;70:511-516. (Pubitemid 24185021)
7. Monga SP, Tang Y, Candotti F et al. Expansion of hepatic and hematopoietic stem cells utilizing mouse embryonic liver explants. Cell Transplant 2001;10:81-89. (Pubitemid 32247073)
8. Suzuki A, Zheng YW, Kaneko S et al. Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver. J Cell Biol 2002;156:173-184. (Pubitemid 34846945)
9. Omori N, Omori M, Evarts RP et al. Partial cloning of rat CD34 cDNA and expression during stem cell-dependent liver regeneration in the adult rat. Hepatology 1997;26:720-727. (Pubitemid 27392364)
10. Suzuki A, Sekiya S, Onishi M et al. Flow cytometric isolation and clonal identification of self-renewing bipotent hepatic progenitor cells in adult mouse liver. Hepatology 2008;48:1964-1978.
11. Nierhoff D, Ogawa A, Oertel M et al. Purification and characterization of mouse fetal liver epithelial cells with high in vivo repopulation capacity. Hepatology 2005;42:130-139. (Pubitemid 40911320)
12. Kubota H, Reid LM. Clonogenic hepatoblasts, common precursors for hepatocytic and biliary lineages, are lacking classical major histocompatibility complex class I antigen. Proc Natl Acad Sci USA 2000;97:12132-12137.
13. Minguet S, Cortegano I, Gonzalo P et al. A population of c-Kit(low)(CD45/TER119)- hepatic cell progenitors of 11-day postcoitus mouse embryo liver reconstitutes cell-depleted liver organoids. J Clin Invest 2003;112:1152-1163. (Pubitemid 38056292)
14. Tanimizu N, Nishikawa M, Saito H et al. Isolation of hepatoblasts based on the expression of Dlk/Pref-1. J Cell Sci 2003;116(Pt 9):1775-1786. (Pubitemid 36582164)
15. Lemmer ER, Shepard EG, Blakolmer K et al. Isolation from human fetal liver of cells co-expressing CD34 haematopoietic stem cell and CAM 5.2 pancytokeratin markers. J Hepatol 1998;29:450-454. (Pubitemid 28396663)
16. Schmelzer E, Zhang L, Bruce A et al. Human hepatic stem cells from fetal and postnatal donors. J Exp Med 2007;204:1973-1987. (Pubitemid 47236331)
17. Weiss TS, Lichtenauer M, Kirchner S et al. Hepatic progenitor cells from adult human livers for cell transplantation. Gut 2008;57:1129-1138.
18. Baumann U, Crosby HA, Ramani P et al. Expression of the stem cell factor receptor c-kit in normal and diseased pediatric liver: Identification of a human hepatic progenitor cell? Hepatology 1999;30:112-117. (Pubitemid 29300576)
19. Malhi H, Irani AN, Gagandeep S et al. Isolation of human progenitor liver epithelial cells with extensive replication capacity and differentiation into mature hepatocytes. J Cell Sci 2002;115(Pt 13):2679-2688. (Pubitemid 34846509)
20. Dan YY, Riehle KJ, Lazaro C et al. Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages. Proc Natl Acad Sci USA 2006;103:9912-9917. (Pubitemid 43993597)
21. Aurich H, Sgodda M, Kaltwasser P et al. Hepatocyte differentiation of mesenchymal stem cells from human adipose tissue in vitro promotes hepatic integration in vivo. Gut 2009;58:570-581.
22. Campard D, Lysy PA, Najimi M et al. Native umbilical cord matrix stem cells express hepatic markers and differentiate into hepatocyte-like cells. Gastroenterology 2008;134:833-848. (Pubitemid 351312728)
23. Novershtern N, Subramanian A, Lawton LN et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell 2011;144:296-309.
24. Seguin CA, Draper JS, Nagy A et al. Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells. Cell Stem Cell 2008;3:182-195.
25. Thorgeirsson SS, Grisham JW. Hematopoietic cells as hepatocyte stem cells: A critical review of the evidence. Hepatology 2006;43:2-8. (Pubitemid 43733584)
26. Zhou P, Wirthlin L, McGee J et al. Contribution of human hematopoietic stem cells to liver repair. Semin Immunopathol 2009;31:411-419.
27. Sato Y, Araki H, Kato J et al. Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion. Blood 2005;106:756-763. (Pubitemid 40981278)
28. Liu C, Wang J, Ou QJ. Possible stem cell origin of human cholangiocarcinoma. World J Gastroenterol 2004;10:3374-3376. (Pubitemid 39585486)
29. Yeh CT, Kuo CJ, Lai MW et al. CD133-positive hepatocellular carcinoma in an area endemic for hepatitis B virus infection. BMC Cancer 2009;9:324.
30. Kakar S, Gown AM, Goodman ZD et al. Best practices in diagnostic immunohistochemistry: Hepatocellular carcinoma versus metastatic neoplasms. Arch Pathol Lab Med 2007;131:1648-1654. (Pubitemid 350077461)
31. Mercer DF, Schiller DE, Elliott JF et al. Hepatitis C virus replication in mice with chimeric human livers. Nat Med 2001;7:927-933. (Pubitemid 32756430)
32. Meuleman P, Libbrecht L, De Vos R et al. Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera. Hepatology 2005;41:847-856. (Pubitemid 40462948)
33. Azuma H, Paulk N, Ranade A et al. Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice. Nat Biotechnol 2007;25:903-910. (Pubitemid 47236918)
34. Washburn ML, Bility MT, Zhang L et al. A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease. Gastroenterology 2011;140:1334-1344.