Effect of H2 blockade and food on single-dose pharmacokinetics of GSK1322322, a peptide deformylase inhibitor antibacterial

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 6, 2013, Pages 2556-2561

  Naderer, Odin J ^a   Dumont, Etienne ^a   Zhu, John ^a   Kurtinecz, Milena ^a   Jones, Lori S ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; GSK1322322; PEPTIDE DEFORMYLASE INHIBITOR; UNCLASSIFIED DRUG;

ADULT; AGED; APPLICATION SITE ERYTHEMA; APPLICATION SITE IRRITATION; AREA UNDER THE CURVE; ARTICLE; DIZZINESS; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG INDUCED HEADACHE; DRUG SAFETY; FLATULENCE; FOOD; GUNSHOT INJURY; HEART PALPITATION; HUMAN; HUMAN EXPERIMENT; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION; UPPER ABDOMINAL PAIN;

ADMINISTRATION, ORAL; ADULT; AMIDOHYDROLASES; ANTI-BACTERIAL AGENTS; ASCORBIC ACID; BIOLOGICAL AVAILABILITY; CROSS-OVER STUDIES; DRUG INTERACTIONS; FEMALE; FOOD-DRUG INTERACTIONS; HISTAMINE H2 ANTAGONISTS; HUMANS; MALE; TABLETS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84877859809     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02505-12     Document Type: Article

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