Feasibility of a breath test for monitoring adherence to vaginal administration of antiretroviral microbicide gels

Journal of Clinical Pharmacology

Volumn 53, Issue 1, 2013, Pages 103-111

  Morey, Timothy E ^a   Wasdo, Scott ^a   Wishin, Judith ^a   Quinn, Brian ^b   Van Der Straten, Ariane ^c,d   Booth, Matthew ^a   Gonzalez, Daniel ^e   Derendorf, Hartmut ^e   Melker, Richard J ^a,b   Dennis, Donn M ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b Xhale Inc   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

Adherence measurement; Biomedical interventions; HIV; Prevention of sexual transmission; Sexual behavior; Vaginal microbicide; Women

Indexed keywords

2 BUTYL ACETATE; 2 PENTYL ACETATE; 2 PENTYL BUTYRATE; ACETIC ACID DERIVATIVE; ALCOHOL; BUTYRIC ACID DERIVATIVE; BUTYRIC ACID ISOPROPYL ESTER; HYDROXYETHYLCELLULOSE; KETONE; MICROBICIDE; PLACEBO; TENOFOVIR; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; BREATH ANALYSIS; COLD SENSATION; CONTROLLED STUDY; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG MONITORING; FEASIBILITY STUDY; FEMALE; GAS CHROMATOGRAPHY; HUMAN; MASS FRAGMENTOGRAPHY; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; METABOLITE; NORMAL HUMAN; PARESTHESIA; PATIENT COMPLIANCE; PILOT STUDY; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINGLE BLIND PROCEDURE; TASTE DISORDER; TIME TO MAXIMUM PLASMA CONCENTRATION; VAGINAL BURNING SENSATION;

ACETATES; ADENINE; ADMINISTRATION, CUTANEOUS; ADMINISTRATION, INTRAVAGINAL; ADOLESCENT; ADULT; ANTI-HIV AGENTS; BREATH TESTS; DRUG MONITORING; FEMALE; HUMANS; MIDDLE AGED; ORGANOPHOSPHONATES; PATIENT COMPLIANCE; VAGINAL CREAMS, FOAMS, AND JELLIES; YOUNG ADULT;

EID: 84877852912     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270011434157     Document Type: Article

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