Gastrointestinal and Extra-Intestinal Manifestations of Childhood Shigellosis in a Region Where All Four Species of Shigella Are Endemic

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Khan, Wasif A ^a   Griffiths, Jeffrey K ^b   Bennish, Michael L ^c  

^a INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Mpilonhle ^*  (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM;

ADOLESCENT; AGE; ARTICLE; CHILD; CLINICAL FEATURE; DISEASE SEVERITY; ENDEMIC SPECIES; FATALITY; FEMALE; GASTROINTESTINAL DISEASE; HEMOLYTIC UREMIC SYNDROME; HOSPITAL ADMISSION; HUMAN; HYPONATREMIA; INFANT; LEUKEMOID REACTION; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; MEDICAL HISTORY; MEDICAL RECORD REVIEW; MORTALITY; NEUROLOGIC DISEASE; PHYSICAL EXAMINATION; PREDICTION; PRESCHOOL CHILD; RECTUM HEMORRHAGE; RECTUM PROLAPSE; SCHOOL CHILD; SEIZURE; SHIGELLA BOYDII; SHIGELLA DYSENTERIAE; SHIGELLA FLEXNERI; SHIGELLA SONNEI; SHIGELLOSIS; SOUTH AFRICA; SPECIES DIFFERENCE; UNCONSCIOUSNESS; ANALYSIS OF VARIANCE; BANGLADESH; DYSENTERY, BACILLARY; GASTROINTESTINAL TRACT; GENETICS; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; REGRESSION ANALYSIS; SHIGELLA;

ADOLESCENT; AGE FACTORS; ANALYSIS OF VARIANCE; BANGLADESH; CHILD; CHILD, PRESCHOOL; DYSENTERY, BACILLARY; GASTROINTESTINAL TRACT; HUMANS; INFANT; REGRESSION ANALYSIS; SHIGELLA; SPECIES SPECIFICITY;

EID: 84877841915     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064097     Document Type: Article

References (46)

1. Bennish ML, Khan WA (2012) Shigellosis. In: Magill AJ, Ryan ET, Hill DR, Solomon T, editors. Hunter's Tropical Medicine and Emerging Infectious Diseases Ninth ed. Maryland: Elsevier Sanders. pp. 454-461.
2. Ram PK, Crump JA, Gupta SK, Miller MA, Mintz ED, (2008) Part II. Analysis of data gaps pertaining to Shigella infections in low and medium human development index countries, 1984-2005. Epidemiol Infect 136: 577-603.
3. von Seidlein L, Kim DR, Ali M, Lee H, Wang X, et al. (2006) A multicentre study of Shigella diarrhoea in six Asian countries: disease burden, clinical manifestations, and microbiology. PLoS Med 3: e353.
4. Kotloff KL, Winickoff JP, Ivanoff B, Clemens JD, Swerdlow DL, et al. (1999) Global burden of Shigella infections: implications for vaccine development and implementation of control strategies. Bull World Health Organ 77: 651-666.
5. Niyogi SK, (2005) Shigellosis. J Microbiol 43: 133-143.
6. Shiga K, (1898) Ueben den Dysenterie bacillus (Bacillus dysenteriae). Zentralbl Bakteriol Parasitenkd Abt I Org 24: 817-824.
7. Hale TL, (1991) Genetic basis of virulence in Shigella species. Microbiol Rev 55: 206-224.
8. Chopra M, Wilkinson D, Stirling S, (1997) Epidemic shigella dysentery in children in northern KwaZulu-Natal. S Afr Med J 87: 48-51.
9. Ashkenazi S, (2004) Shigella infections in children: new insights. Semin Pediatr Infect Dis 15: 246-252.
10. Koster F, Levin J, Walker L, Tung KS, Gilman RH, et al. (1978) Hemolytic-uremic syndrome after shigellosis. Relation to endotoxemia and circulating immune complexes. N Engl J Med 298: 927-933.
11. Rahaman MM, JamiulAlam AK, Islam MR, Greenough WB 3rd (1975) Shiga bacillus dysentery associated with marked leukocytosis and erythrocyte fragmentation. Johns Hopkins Med J 136: 65-70.
12. Bennish ML, Azad AK, Yousefzadeh D, (1991) Intestinal obstruction during shigellosis: incidence, clinical features, risk factors, and outcome. Gastroenterology 101: 626-634.
13. O'Loughlin EV, Robins-Browne RM, (2001) Effect of Shiga toxin and Shiga-like toxins on eukaryotic cells. Microbes Infect 3: 493-507.
14. Khan WA, Dhar U, Salam MA, Griffiths JK, Rand W, et al. (1999) Central nervous system manifestations of childhood shigellosis: prevalence, risk factors, and outcome. Pediatrics 103: E18.
15. Bennish ML, (1991) Potentially lethal complications of shigellosis. Rev Infect Dis 13Suppl 4: S319-324.
16. Bennish ML, Harris JR, Wojtyniak BJ, Struelens M, (1990) Death in shigellosis: incidence and risk factors in hospitalized patients. J Infect Dis 161: 500-506.
17. CDC (2000) National Center for Health Statistics- Clinical Growth Charts. Available: http://www.cdc.gov/nchs/about/major/nhanes/growthcharts/clinical_charts.htm. Accessed 2005 Oct 15.
18. Salam MA, Bennish ML, (1988) Therapy for shigellosis. I. Randomized, double-blind trial of nalidixic acid in childhood shigellosis. J Pediatr 113: 901-907.
19. Ahmed F, Clemens JD, Rao MR, Ansaruzzaman M, Haque E, (1997) Epidemiology of shigellosis among children exposed to cases of Shigella dysentery: a multivariate assessment. Am J Trop Med Hyg 56: 258-264.
20. Huskins WC, Griffiths JK, Faruque AS, Bennish ML, (1994) Shigellosis in neonates and young infants. J Pediatr 125: 14-22.
21. Jennison AV, Verma NK, (2004) Shigella flexneri infection: pathogenesis and vaccine development. FEMS Microbiol Rev 28: 43-58.
22. Faruque AS, Teka T, Fuchs GJ, (1998) Shigellosis in children: a clinico-epidemiological comparison between Shigella dysenteriae type I and Shigella flexneri. Ann Trop Paediatr 18: 197-201.
23. de Silva DG, Mendis LN, Sheron N, Alexander GJ, Candy DC, et al. (1993) Concentrations of interleukin 6 and tumour necrosis factor in serum and stools of children with Shigella dysenteriae 1 infection. Gut 34: 194-198.
24. Thorpe CM, Smith WE, Hurley BP, Acheson DW, (2001) Shiga toxins induce, superinduce, and stabilize a variety of C-X-C chemokine mRNAs in intestinal epithelial cells, resulting in increased chemokine expression. Infect Immun 69: 6140-6147.
25. Keusch GT, (1977) Bacterial toxins as virulence factors: Shiga bacillus dysentery viewed as a toxinosis. Mt Sinai J Med 44: 33-41.
26. Fasano A, Noriega FR, Liao FM, Wang W, Levine MM, (1997) Effect of shigella enterotoxin 1 (ShET1) on rabbit intestine in vitro and in vivo. Gut 40: 505-511.
27. Kotloff KL, Pasetti MF, Barry EM, Nataro JP, Wasserman SS, et al. (2004) Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208. J Infect Dis 190: 1745-1754.
28. Bennish ML, Salam MA, Wahed MA, (1993) Enteric protein loss during shigellosis. Am J Gastroenterol 88: 53-57.
29. Constantinescu AR, Bitzan M, Weiss LS, Christen E, Kaplan BS, et al. (2004) Non-enteropathic hemolytic uremic syndrome: causes and short-term course. Am J Kidney Dis 43: 976-982.
30. Bennish ML KI, Khan AM, Azad AK, Robertson G (1988) Hyponatremia in shigellosis: incidence and mechanisms. 28th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). Los Angeles, California.
31. Legros D, Paquet C, Dorlencourt F, Saoult E, (1999) Risk factors for death in hospitalized dysentery patients in Rwanda. Trop Med Int Health 4: 428-432.
32. Nathoo KJ, Porteous JE, Siziya S, Wellington M, Mason E, (1998) Predictors of mortality in children hospitalized with dysentery in Harare, Zimbabwe. Cent Afr J Med 44: 272-276.
33. van den Broek JM, Roy SK, Khan WA, Ara G, Chakraborty B, et al. (2005) Risk factors for mortality due to shigellosis: a case-control study among severely-malnourished children in Bangladesh. J Health Popul Nutr 23: 259-265.
34. Mitra AK, Engleberg NC, Glass RI, Chowdhury MK, (1990) Fatal dysentery in rural Bangladesh. J Diarrhoeal Dis Res 8: 12-17.
35. Kavaliotis J, Karyda S, Konstantoula T, Kansouzidou A, Tsagaropoulou H, (2000) Shigellosis of childhood in northern Greece: epidemiological, clinical and laboratory data of hospitalized patients during the period 1971-96. Scand J Infect Dis 32: 207-211.
36. Bardhan P, Faruque AS, Naheed A, Sack DA, (2010) Decrease in shigellosis-related deaths without Shigella spp.-specific interventions, Asia. Emerg Infect Dis 16: 1718-1723.
37. Bennish ML, Khan WA, Begum M, Bridges EA, Ahmed S, et al. (2006) Low risk of hemolytic uremic syndrome after early effective antimicrobial therapy for Shigella dysenteriae type 1 infection in Bangladesh. Clin Infect Dis 42: 356-362.
38. Huang IF, Chiu CH, Wang MH, Wu CY, Hsieh KS, et al. (2005) Outbreak of dysentery associated with ceftriaxone-resistant Shigella sonnei: First report of plasmid-mediated CMY-2-type AmpC beta-lactamase resistance in S. sonnei. J Clin Microbiol 43: 2608-2612.
39. National Institute of Population Research and Training (NIPORT), Mitra and Associates a, International I (2013) Bangladesh Demographic and Health Survey 2011. Dhaka, Bangladesh and Calverton, Maryland, USA: NIPORT, Mitra and Associates, and ICF International.
40. Trofa AF, Ueno-Olsen H, Oiwa R, Yoshikawa M, (1999) Dr. Kiyoshi Shiga: discoverer of the dysentery bacillus. Clin Infect Dis 29: 1303-1306.
41. Barrett-Connor E, Connor JD, (1970) Extraintestinal manifestations of shigellosis. Am J Gastroenterol 53: 234-245.
42. Chisti MJ, Faruque AS, Khan WA, Das SK, Zabed MB, et al. (2010) Characteristics of children with Shigella encephalopathy: experience from a large urban diarrhea treatment center in Bangladesh. Pediatr Infect Dis J 29: 444-447.
43. Biedner B, Rosenblatt I, Dugan R, Yassur Y, (1987) Corneal ulcer caused by Shigella flexneri in an infant. Am J Ophthalmol 104: 90.
44. Baiulescu M, Hannon PR, Marcinak JF, Janda WM, Schreckenberger PC, (2002) Chronic vulvovaginitis caused by antibiotic-resistant Shigella flexneri in a prepubertal child. Pediatr Infect Dis J 21: 170-172.
45. Papasian CJ, Enna-Kifer S, Garrison B, (1995) Symptomatic Shigella sonnei urinary tract infection. J Clin Microbiol 33: 2222-2223.
46. Mazumder RN, Salam MA, Ali M, Bhattacharya MK, (1997) Reactive arthritis associated with Shigella dysenteriae type 1 infection. J Diarrhoeal Dis Res 15: 21-24.