Effects of age, sex, and sertraline administration on seizure-induced respiratory arrest in the DBA/1 mouse model of sudden unexpected death in epilepsy (SUDEP)

Epilepsy and Behavior

Volumn 28, Issue 1, 2013, Pages 78-82

  Faingold, Carl L ^a   Randall, Marcus ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Age; DBA 1 mice; Development; Respiratory arrest; Sertraline; Sex; SSRI; SUDEP

Indexed keywords

SERTRALINE;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DISEASE PREDISPOSITION; FEMALE; MALE; MOUSE; NONHUMAN; PERINATAL PERIOD; RESPIRATORY ARREST; SEIZURE; SEX DIFFERENCE; SUDDEN DEATH;

ACOUSTIC STIMULATION; AGING; ANIMALS; DEATH, SUDDEN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY, REFLEX; FEMALE; MALE; MICE; MICE, INBRED DBA; RESPIRATORY INSUFFICIENCY; SEROTONIN UPTAKE INHIBITORS; SERTRALINE; SEX CHARACTERISTICS;

EID: 84877834105     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2013.04.003     Document Type: Article

References (40)

1. Hughes J.R. A review of sudden unexpected death in epilepsy: prediction of patients at risk. Epilepsy Behav 2009, 14(2):280-287.
2. Asadi-Pooya A.A., Sperling M.R. Clinical features of sudden unexpected death in epilepsy. J Clin Neurophysiol 2009, 26(5):297-301.
3. Sperling M.R. Sudden unexplained death in epilepsy. Epilepsy Curr 2001, 1(1):21-23.
4. Surges R., Sander J.W. Sudden unexpected death in epilepsy: mechanisms, prevalence, and prevention. Curr Opin Neurol 2012, 25(2):201-207.
5. Shorvon S., Tomson T. Sudden unexpected death in epilepsy. Lancet 2011, 378(9808):2028-2038.
6. Donner E.J. Explaining the unexplained; expecting the unexpected: where are we with sudden unexpected death in epilepsy?. Epilepsy Curr 2011, 11(2):45-49.
7. Lhatoo S.C., Faulkner H.J., Dembny K., Trippick K., Johnson C., Bird J.M. An electroclinical case-control study of sudden unexpected death in epilepsy. Ann Neurol 2010, 68(6):787-796.
8. Richerson G.B., Buchanan G.F. The serotonin axis: shared mechanisms in seizures, depression, and SUDEP. Epilepsia 2011, 52(Suppl. 1):28-38.
9. Bateman L.M., Li C.S., Seyal M. Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors. Brain 2008, 31(Pt 12):3239-3245.
10. Venit E.L., Shepard B.D., Seyfried T.N. Oxygenation prevents sudden death in seizure-prone mice. Epilepsia 2004, 45:993-996.
11. Tupal S., Faingold C.L. Evidence supporting a role of serotonin in modulation of sudden death induced by seizures in DBA/2 mice. Epilepsia 2006, 47:21-22.
12. Shen H.Y., Li T., Boison D. A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance. Epilepsia 2010, 51(3):465-468.
13. Scorza F.A., Albuquerque R., Arida R.M., Albuquerque M., Terra V.C., Machado H.R., et al. What are the similarities between stress, sudden cardiac death in Gallus gallus and sudden unexpected death in people with epilepsy?. Arq Neuropsiquiatr 2010, 68(5):788-790.
14. Faingold C.L., Randall M., Tupal S. DBA/1 mice exhibit chronic susceptibility to audiogenic seizures followed by sudden death associated with respiratory arrest. Epilepsy Behav 2010, 17(4):436-440.
15. Faingold C.L., Tupal S., Mhaskar Y., Uteshev V.V. DBA mice as models of sudden unexpected death in epilepsy. Sudden death in epilepsy: forensic and clinical issue 2010, 657-674. Taylor and Francis, Boca Raton, FL. C. Lathers, P. Schraeder, M. Bungo, J. Leestma (Eds.).
16. Tomson T., Nashef L., Ryvlin P. Sudden unexpected death in epilepsy: current knowledge and future directions. Lancet Neurol 2008, 7(11):1021-1031.
17. Blum A.S. Respiratory physiology of seizures. J Clin Neurophysiol 2009, 26(5):309-315.
18. Bateman L.M., Spitz M., Seyal M. Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: report on two deaths in video-EEG-monitored patients. Epilepsia 2010, 51(5):916-920.
19. Faingold C.L., Tupal S., Randall M. Prevention of seizure-induced sudden death in a chronic SUDEP model by semi-chronic administration of a selective serotonin reuptake inhibitor. Epilepsy Behav 2011, 22(2):186-190.
20. Faingold C.L., Randall M., Mhaskar Y., Uteshev V.V. Differences in serotonin receptor expression in the brainstem may explain the differential ability of a serotonin agonist to block seizure-induced sudden death in DBA/2 vs. DBA/1 mice. Brain Res 2011, 1418:104-110.
21. Tupal S., Faingold C. Inhibition of adenylyl cyclase in amygdala blocks the effect of audiogenic seizure kindling in genetically epilepsy-prone rats. Neuropharmacology 2010, 59(1-2):107-111.
22. Yagi H., Takamura Y., Yoneda T., Konno D., Akagi Y., Yoshida K., Sato M. Vlgr1 knockout mice show audiogenic seizure susceptibility. J Neurochem 2005, 92(1):191-202.
23. Bateman L.M., Li D.S., Li N.T.C., Seyal M. Serotonin reuptake inhibitors are associated with reduced severity of ictal hypoxemia in medically refractory partial epilepsy. Epilepsia 2010, 51(10):2211-2214.
24. Uteshev V.V., Tupal S., Mhaskar Y., Faingold C.L. Abnormal serotonin receptor expression in DBA/2 mice associated with susceptibility to sudden death due to respiratory arrest. Epilepsy Res 2010, 88(2-3):183-188.
25. Fisher R.S., Schachter S.C. The postictal state: a neglected entity in the management of epilepsy. Epilepsy Behav 2000, 1:52-59.
26. Begg M., Dale N., Llaudet E., Molleman A., Parsons M.E. Modulation of the release of endogenous adenosine by cannabinoids in the myenteric plexus-longitudinal muscle preparation of the guinea-pig ileum. Br J Pharmacol 2002, 137(8):1298-1304.
27. Zwicker J.D., Rajani V., Hahn L.B., Funk G.D. Purinergic modulation of preBötzinger complex inspiratory rhythm in rodents: the interaction between ATP and adenosine. J Physiol 2011, 589(Pt 18):4583-4600.
28. 2 chemoreception, and thermoregulation. J Appl Physiol 2010, 108(5):1425-1432.
29. Benarroch E.E. Brainstem respiratory control: substrates of respiratory failure of multiple system atrophy. Mov Disord 2007, 22(2):155-161.
30. 2. Proc Natl Acad Sci U S A 2010, 107(37):16354-16359.
31. Moseley B.D., Nickels K., Britton J., Wirrell E. How common is ictal hypoxemia and bradycardia in children with partial complex and generalized convulsive seizures?. Epilepsia 2010, 51(7):1219-1224.
32. Nei M., Hays R. Sudden unexpected death in epilepsy. Curr Neurol Neurosci Rep 2010, 10(4):319-326.
33. Hodges M.R., Richerson G.B. Contributions of 5-HT neurons to respiratory control: neuromodulatory and trophic effects. Respir Physiol Neurobiol 2008, 164(1-2):222-232.
34. Applegate C.D., Tecott L.H. Global increases in seizure susceptibility in mice lacking 5-HT2C receptors: a behavioral analysis. Exp Neurol 1998, 154:522-530.
35. Moon R.Y., Horne R.S., Hauck F.R. Sudden infant death syndrome. Lancet 2007, 370(9598):1578-1587.
36. Jobe P.C., Browning R.A. The serotonergic and noradrenergic effects of antidepressant drugs are anticonvulsant, not proconvulsant. Epilepsy Behav 2005, 7(4):602-619.
37. Richman A., Heinrichs S.C. Seizure prophylaxis in an animal model of epilepsy by dietary fluoxetine supplementation. Epilepsy Res 2007, 74(1):19-27.
38. Pisani F., Oteri G., Costa C., Di Raimondo G., Di Perri R. Effects of psychotropic drugs on seizure threshold. Drug Saf 2002, 25(2):91-110.
39. Windischberger C., Lanzenberger R., Holik A., Spindelegger C., Stein P., Moser U., et al. Area-specific modulation of neural activation comparing escitalopram and citalopram revealed by pharmaco-fMRI: a randomized cross-over study. Neuroimage 2010, 49(2):1161-1170.
40. Surges R., Adjei P., Kallis C., Erhuero J., Scott C.A., Bell G.S., et al. Pathologic cardiac repolarization in pharmacoresistant epilepsy and its potential role in sudden unexpected death in epilepsy: a case-control study. Epilepsia 2010, 51(2):233-242.