Regulation and function of C1Q/TNF-related protein-5 (CTRP-5) in the context of adipocyte biology

Experimental and Clinical Endocrinology and Diabetes

Volumn 121, Issue 5, 2013, Pages 310-317

  Schmid, A ^a   Kopp, A ^a   Aslanidis, C ^a   Wabitsch, M ^b   Muller M ^a   Schaffler A ^a  

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

adipocyte; adipokine; adipose tissue; CTRP 5; single nucleotide polymorphism

Indexed keywords

ADIPONECTIN; C1Q TNF RELATED PROTEIN 5; COMPLEMENT COMPONENT C1Q; FATTY ACID; MESSENGER RNA; RECOMBINANT PROTEIN; RESISTIN; SATURATED FATTY ACID; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CAUCASIAN; CELL DIFFERENTIATION; CELL STRAIN 3T3; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLOGY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; UPREGULATION; WESTERN BLOTTING;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ADULT; ANIMALS; CASE-CONTROL STUDIES; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; FEMALE; GENE EXPRESSION REGULATION; GENE FREQUENCY; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, SMALL INTERFERING; YOUNG ADULT;

EID: 84877825180     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0032-1333299     Document Type: Article

References (21)

1. Schaffler A., Buechler C. CTRP family: linking immunity to metabolism. Trends Endocrinol Metab: 2012; 23 194 204
2. Kadowaki T., Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev: 2005; 26 439 451 (Pubitemid 40686653)
3. Scherer P. E. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes: 2006; 55 1537 1545 (Pubitemid 44324105)
4. Wong G. W., Wang J., Hug C. et al. A family of Acrp30/adiponectin structural and functional paralogs. Proc Natl Acad Sci USA: 2004; 101 10302 10307 (Pubitemid 38924920)
5. Kishore U., Gaboriaud C., Waters P. et al. C1q and tumor necrosis factor superfamily: modularity and versatility. Trends Immunol: 2004; 25 551 561 (Pubitemid 39208354)
6. Shapiro L., Scherer P. E. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr Biol: 1998; 8 335 338 (Pubitemid 28159119)
7. Kopp A., Bala M., Buechler C. et al. C1q/TNF-related protein-3 represents a novel and endogenous lipopolysaccharide antagonist of the adipose tissue. Endocrinology: 2010; 151 5267 5278
8. Kopp A., Bala M., Weigert J. et al. Effects of the new adiponectin paralogous protein CTRP-3 and of LPS on cytokine release from monocytes of patients with type 2 diabetes mellitus. Cytokine: 2011; 49 51 57
9. Peterson J. M., Wei Z., Wong G. W. C1q/TNF-related protein-3 (CTRP3), a novel adipokine that regulates hepatic glucose output. J Biol Chem: 2011; 285 39691 39701
10. Lee Y. H., Nair S., Rousseau E. et al. Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes. Diabetologia: 2005; 48 1776 1783 (Pubitemid 41317831)
11. Yamada Y., Ichihara S., Kato K. et al. Genetic risk for metabolic syndrome: examination of candidate gene polymorphisms related to lipid metabolism in Japanese people. J Med Genet: 2008; 45 22 28 (Pubitemid 351158154)
12. Wong G. W., Krawczyk S. A., Kitidis-Mitrokostas C. et al. Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions. Biochem J: 2008; 416 161 177
13. Wong G. W., Krawczyk S. A., Kitidis-Mitrokostas C. et al. Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. FASEB J: 2009; 23 241 258
14. Wei Z., Peterson J. M., Lei X. et al. C1q/TNF-related Protein-12 (CTRP12), a Novel Adipokine That Improves Insulin Sensitivity and Glycemic Control in Mouse Models of Obesity and Diabetes. J Biol Chem: 2012; 287 10301 10315
15. Park S. Y., Choi J. H., Ryu H. S. et al. C1q tumor necrosis factor alpha-related protein isoform 5 is increased in mitochondrial DNA-depleted myocytes and activates AMP-activated protein kinase. J Biol Chem: 2009; 284 27780 27789
16. Bala M., Martin J., Kopp A. et al. In vivo suppression of visfatin by oral glucose uptake: evidence for a novel incretin-like effect by glucagon-like peptide-1 (GLP-1). J Clin Endocrinol Metab: 2011; 96 2493 2501
17. Green H., Kehinde O. An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell: 1975; 5 19 27
18. Wabitsch M., Brenner R. E., Melzner I. et al. Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation. Int J Obes Relat Metab Disord: 2001; 25 8 15 (Pubitemid 32142378)
19. Kopp A., Gross P., Falk W. et al. Fatty acids as metabolic mediators in innate immunity. Eur J Clin Invest: 2009; 39 924 933
20. Schaeffler A., Gross P., Buettner R. et al. Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity. Immunology: 2009; 126 233 245
21. Lim S., Choi S. H., Koo B. K. et al. Effects of aerobic exercise training on C1q tumor necrosis factor alpha-related protein isoform 5 (myonectin): association with insulin resistance and mitochondrial DNA density in women. J Clin Endocrinol Metab: 2012; 97 E88 E93