Rapamycin preserves the follicle pool reserve and prolongs the ovarian lifespan of female rats via modulating mTOR activation and sirtuin expression

Gene

Volumn 523, Issue 1, 2013, Pages 82-87

  Zhang, Xing mei ^a   Li, Li ^a   Xu, Jin jie ^a   Wang, Na ^a   Liu, Wei juan ^a   Lin, Xuan hao ^b   Fu, Yu cai ^a   Luo, Li li ^a  

^a SHANTOU UNIVERSITY   (China)

^b SHANTOU CENTRAL HOSPITAL   (China)

Author keywords

Follicle; MTOR; Ovarian lifespan; Rapamycin; Sirtuins

Indexed keywords

EOSIN; HEMATOXYLIN; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; SIRTUIN;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; IMMUNOHISTOCHEMISTRY; LIFESPAN; NONHUMAN; OVARY FOLLICLE; OVARY FOLLICLE DEVELOPMENT; PRECAMBRIAN; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

ANIMALS; BODY WEIGHT; CYTOPLASM; EATING; EOSINE YELLOWISH-(YS); ESTROUS CYCLE; FEMALE; FERTILITY; HEMATOXYLIN; MALE; OOCYTES; ORGAN SIZE; OVARIAN FOLLICLE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; SIROLIMUS; SIRTUIN 2; SIRTUINS; TIME FACTORS; TOR SERINE-THREONINE KINASES;

RATTUS;

EID: 84877816563     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2013.03.039     Document Type: Article

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