Influence of the grain size on the in vivo degradation behaviour of the magnesium alloy LAE442

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine

Volumn 227, Issue 3, 2013, Pages 317-326

  Ullmann, Berit ^a   Reifenrath, Janin ^a   Seitz, Jan Marten ^b   Bormann, Dirk ^b   Meyer Lindenberg, Andrea ^c  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b LEIBNIZ UNIVERSITY HANNOVER   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Biodegradable; Grain size; In vivo; Magnesium

Indexed keywords

BIODEGRADABLE; DAMAGED SURFACES; ENERGY DISPERSIVE X-RAY; GRAIN SIZE; IMPLANT MATERIALS; IN-VIVO; IN-VIVO CORROSION; INITIAL STABILITIES; SURFACE DAMAGES;

CORROSION RATE; MAGNESIUM; MAGNESIUM ALLOYS; RADIOLOGY; SCANNING ELECTRON MICROSCOPY; SURFACES; X RAY ANALYSIS; CORROSION; ENERGY DISPERSIVE X RAY ANALYSIS; GRAIN SIZE AND SHAPE;

GRAIN SIZE AND SHAPE; MAGNESIUM;

ALLOY; MAGNESIUM;

ANIMAL; ARTICLE; BIODEGRADABLE IMPLANT; BONE NAIL; BONE PROSTHESIS; CHEMISTRY; MATERIALS TESTING; METABOLISM; RABBIT; RADIOGRAPHY; SURFACE PROPERTY; TIBIA;

ABSORBABLE IMPLANTS; ALLOYS; ANIMALS; BONE NAILS; BONE SUBSTITUTES; MAGNESIUM; MATERIALS TESTING; RABBITS; SURFACE PROPERTIES; TIBIA;

MLCS; MLOWN;

EID: 84877795396     PISSN: 09544119     EISSN: 20413033     Source Type: Journal    
DOI: 10.1177/0954411912471495     Document Type: Article

References (37)

1. Thomann M, Krause C, Bormann D, et al. Comparison of the resorbable magnesium alloys LAE442 und MgCa0.8 concerning their mechanical properties, their progress of degradation and the bone-implant-contact after 12 months implantation duration in a rabbit model. Mater Sci Eng Technol 2009; 40: 82-87.
2. Staiger MP, Pietak AM, Huadmai J, et al. Magnesium and its alloys as orthopedic biomaterials: a review. Biomaterials 2006; 27: 1728-1734. (Pubitemid 41760433)
3. Huehnerschulte TA, Angrisani N, Rittershaus D, et al. In vivo corrosion of two novel magnesium alloys ZEK100 and AX30 and their mechanical suitability as biodegradable implants. Materials 2011; 4: 1144-1167.
4. Witte F, Kaese V, Haferkamp H, et al. In vivo corrosion of four magnesium alloys and the associated bone response. Biomaterials 2005; 26: 3557-3563. (Pubitemid 40038150)
5. Zeng R, Dietzel W, Witte F, et al. Progress and challenge for magnesium alloys as biomaterials. Adv Eng Mater 2008; 10: B3-B14.
6. Reifenrath J, Krause A, Bormann D, et al. Profound differences in the in-vivo-degradation and biocompatibility of two very similar rare-earth containing Mg-alloys in a rabbit model. Materwiss Werksttech 2010; 41: 1054-1061.
7. Hampp C, Ullmann B, Reifenrath J, et al. Research on the biocompatibility of the new magnesium alloy LANd442 - an in vivo study in the rabbit tibia over 26 weeks. Adv Eng Mater 2012; 14: B28-B37.
8. Witte F, Hort N, Vogt C, et al. Degradable biomaterials based on magnesium corrosion. Curr Opin Solid State Mater Sci 2008; 12: 63-72.
9. Salgado AJ, Coutinho OP and Reis RL. Bone tissue engineering: state of the art and future trends. Macromol Biosci 2004; 4: 743-765. (Pubitemid 39257140)
10. Hofmann GO. Biodegradable implants in traumatology: a review on the state-of-the-art. Arch Orthop Trauma Surg 1995; 114: 123-132.
11. Song G and Atrens A. Understanding magnesium corrosion - a framework for improved alloy performance. Adv Eng Mater 2003; 5: 837-858.
12. Yazhong Z, Pan F, Peng J, et al. Effect of neodymium on the as-extruded ZK20 magnesium alloy. J Rare Earth 2010; 28: 631-635.
13. Tong G, Liu H and Liu Y. Effect of rare earth additions on microstructure and mechanical properties of AZ91 magnesium alloys. T Nonferr Metal Soc 2010; 20: 336-340.
14. Von der Höh N, Bormann D, Lucas A, et al. Influence of different surface machining treatments of magnesiumbased resorbable implants on the degradation behavior in rabbits. Adv Eng Mater 2009; 11: B47-B54.
15. Kannan MB, Singh Raman RK, Witte F, et al. Influence of circumferential notch and fatigue crack on the mechanical integrity of biodegradable magnesium-based alloy in simulated body fluid. J Biomed Mater Res B Appl Biomater 2010; 96: 303-309.
16. Alvarez-Lopez M, Pereda MD, Del Valle JA, et al. Corrosion behaviour of AZ31 magnesium alloy with different grain sizes in simulated biological fluids. Acta Biomater 2009; 6: 1763-1771.
17. Jiang B, Gao L, Huang G, et al. Effect of extrusion processing parameters on microstructure and mechanical properties of as-extruded AZ31 sheets. T Nonferr Metal Soc 2008; 18: 160-164.
18. Chen Y, Wang Q, Peng J, et al. Effects of extrusion ratio on the microstructure and mechanical properties of AZ31 Mg alloy. J Mater Process Tech 2007; 182: 281-285. (Pubitemid 44693303)
19. Shahzad M and Wagner L. Influence of extrusion parameters on microstructure and texture developments, and their effects on mechanical properties of the magnesium alloy AZ80. Mater Sci Eng 2009; 506: 141-147.
20. Witte F, Fischer J, Nellesen J, et al. In vitro and in vivo corrosion measurements of magnesium alloys. Biomaterials 2006; 27: 1013-1018. (Pubitemid 41566693)
21. Krause A, Von der Höh N, Bormann D, et al. Degradation behaviour and mechanical properties of magnesium implants in rabbit tibiae. J Mater Sci 2010; 45: 624-632.
22. Ullmann B, Reifenrath J, Dziuba D, et al. In vivo degradation behaviour of the magnesium alloy LANd442 in rabbit tibiae. Materials 2011; 4: 2197-2218.
23. Witte F, Fischer J, Nellesen J, et al. In vivo corrosion and corrosion protection of magnesium alloy LAE442. Acta Biomater 2010; 6: 1792-1799.
24. Makar G and Kruger J. Corrosion of magnesium. Int Mater Rev 1993; 38: 138-153. (Pubitemid 23680521)
25. Song G. Recent progress in corrosion and protection of magnesium alloys. Adv Eng Mater 2005; 7: 563-586. (Pubitemid 41130338)
26. Atrens A, Liu M and Zainal AN. Corrosion mechanism applicable to biodegradable magnesium implants. Mater Sci Eng B: Adv 2011; 176: 1609-1636.
27. Zhang E, Xu L, Yu G, et al. In vivo evaluation of biodegradable magnesium alloy bone implant in the first 6 months implantation. J Biomed Mater Res A 2009; 90: 882-893.
28. Li L, Gao J and Wang Y. Evaluation of cyto-toxicity and corrosion behavior of alkali-heat-treated magnesium in simulated body fluid. Surf Coat Technol 2004; 185: 92-98. (Pubitemid 38804463)
29. Song Y, Shan D, Chen R, et al. Biodegradable behaviors of AZ31 magnesium alloys in simulated body fluid. Mater Sci Eng C Mater Biol Appl 2009; 29: 1039-1045.
30. ASTM G31-72:2004. Standard practice for laboratory immersion corrosion testing of metals. American Society for Testing and Materials.
31. Dziuba D, Meyer-Lindenberg A, Seitz J-M, et al. Long term in vivo degradation behaviour and biocompatibility of the magnesium alloy ZEK100 for use as biodegradable bone implant. Acta Biomater. Epub ahead of print 23 August 2012. DOI: 10.1016/j.actbio.2012.08.028.
32. Lambotte A. L'utilisation du magnesium comme materiel perdu dans l'osteosynthèse. Bull Mém Soc Nat Chir 1932; 28: 1325-1334.
33. McBride ED. Absorbable metal in bone surgery. JAMA 1938; 111: 2464-2467.
34. Sugiyama T, Price JS and Lanyon LE. Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones. Bone 2010; 46: 314-321.
35. Lambers FM, Schulte FA, Kuhn G, et al. Mouse tail vertebrae adapt to cyclic mechanical loading by increasing bone formation rate and decreasing bone resorption rate as shown by time-lapsed in vivo imaging of dynamic bone morphometry. Bone 2011; 49: 1340-1350.
36. Witte F, Ulrich H, Palm C, et al. Biodegradable magnesium scaffolds: part II: peri-implant bone remodeling. J Biomed Mater Res A 2007; 81: 757-765. (Pubitemid 46786908)
37. Kubota K. Review processing and mechanical properties of fine-grained magnesium alloys. J Mater Sci 1999; 34: 2255-2262.